Steroidal aerosol compositions and process for the preparation thereof
Patent 4044126 Issued on August 23, 1977. Estimated Expiration Date: 
August 23, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 23, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3312590 3721687 InventorsAssigneeApplicationNo. 703821 filed on 07/09/1976US Classes:514/180, 9-position substituted514/957VAPOR EMMITTING COMPOSITIONExaminersPrimary: Roberts, Elbert L.Attorney, Agent or FirmInternational ClassA61K 031/56Foreign Application Priority Data1972-04-20 UKAbstractAn antiinflammatory steroid exhibiting a tendency to crystal growth in suspension in aerosol propellants is contacted with a halogenated hydrocarbon to form a crystalline solvate, which, after removal of some or all of the propellant from the crystals, is reduced to a particle size permitting inhalation into the human bronchial system when dispersed as an aerosol, the micronized crystalline solvate not thereafter exhibiting crystal growth in the aerosol propellant. The solvate is a new composition of matter which has been characterized by I.R. spectra and the aerosol formulation prepared therefrom has valuable therapeutic properties, particularly in the treatment of asthma.Other References
| |
