Immunoassay for pharmacologically active phenethylamines
Patent 4041076 Issued on August 9, 1977. Estimated Expiration Date: August 9, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
564/114, Haloamines (i.e., compounds containing halogen attached directly to amino nitrogen by nonionic bonding)436/804, RADIOISOTOPE (E.G., RADIOIMMUNOASSAY, ETC.)530/405, Nitrogen containing reactant530/807, HAPTEN CONJUGATED WITH PEPTIDE OR PROTEIN560/29, Oxy in acid moiety564/165, Hydroxy, bonded directly to carbon, or ether in substituent Q (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)564/219A ring or polycyclo ring system in a substituent E is attached indirectly to the carboxamide nitrogen or to an amino nitrogen in substituent E by acyclic nonionic bonding
New hapten compositions useful in preparing antigens which may be employed in eliciting antibodies useful in an improved radioimmunoassay for pharmacologically active phenethylamines are disclosed. Particular phenethylamins which are preferably detected by the present radioimmunoassay include the catecholamines such as norepinephrine, dopamine and epinephrine, and the amphetamines.