Iodothyronine enzyme conjugates
Patent 4040907 Issued on August 9, 1977. Estimated Expiration Date: 
August 9, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
August 9, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3839153 3850752 InventorsAssigneeApplicationNo. 644489 filed on 12/29/1975US Classes:435/188, Stablizing an enzyme by forming a mixture, an adduct or a composition, or formation of an adduct or enzyme conjugate435/12, Involving urea or urease435/18, Involving hydrolase435/20, Involving cholinesterase435/21, Involving phosphatase435/22, Involving amylase435/23, Involving proteinase435/24, Involving peptidase435/25, Involving oxidoreductase435/26Involving dehydrogenaseExaminersPrimary: Tanenholtz, Alvin E.Attorney, Agent or FirmInternational ClassC07G 007/02AbstractPolyiodothyronine conjugates to enzymes are provided which find use in the determination of polyiodothyronine compounds, particularly thyroxine, normally in physiological fluids, such as serum. The enzymes can provide substantial variation in activity when bound to protein receptors for polyiodothyronine as compared to the free or unbound polyiodothyronine conjugated to the enzyme. Various linking groups are provided for linking the polyiodothyronine to the enzyme.Other References
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