Patent References 3654291 3853897 3894151 3898335 3923809 InventorsAssigneeApplicationNo. 05/619724 filed on 10/06/1975US Classes:546/275.1, Chalcogen attached indirectly to the 1,3-diazole ring by acyclic nonionic bonding514/849, COUGH AND COLD PREPARATION544/182, Asymmetrical (e.g., 1, 2, 4-triazines, etc.)544/284, Additional nitrogen containing unsaturated hetero ring (e.g., thiazole, etc.)544/317, The nitrogen is bonded directly at 4- or 6-position544/319, At 4- or 6-position544/8, Thiadiazines544/9, Polycyclo ring system having the thiadiazine ring as one of the cyclos546/153, Chalcogen attached directly to the six-membered hetero ring by nonionic bonding546/272.7, 1,3-diazoles (including hydrogenated)546/274.4, Chalcogen attached directly to the 1,3-diazole ring by nonionic bonding546/274.7Nitrogen or -C(=X)-, wherein X is chalcogen, attached directly to the 1,3-diazole diazole ring by nonionic bondingExaminersPrimary: Rotman, Alan L.Attorney, Agent or FirmForeign Application Priority Data1973-05-03 UKAbstractHeterocyclic compounds which are inhibitors of histamine activity, in particular, inhibitors of H-2 histamine receptors. A specific compound of this invention is 2-[2-(4-methyl-5-imidazolylmethylthio)ethylamino]-4-pyrimidone. |
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