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US Patent 4025501 - Polypeptide propoxyphene derivatives for immunoassay reagents
US Patent Issued on May 24, 1977
Estimated Patent Expiration Date:
May 24, 1994Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
Estimated Patent Expiration Date:
May 24, 1994Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.AbstractNovel compounds are provided which are derivatives of 1,2-diphenyl-3-methyl-4-dimethylamino-2-butanol. The indicated alcohol is employed to prepare the monoester of a dibasic acid which is conjugated with an antigen for the production of antibodies which recognize both propoxyphene and its N-desmethyl metabolite in immunoassays.Other References
| InventorAssigneeApplicationNo. 05/560079 filed on 03/20/1975US Classes:530/363, Serum albumin, e.g., BSA, HSA, etc.435/7.9, Assay in which an enzyme present is a label435/961, INCLUDING A STEP OF FORMING, RELEASING, OR EXPOSING THE ANTIGEN OR FORMING THE HAPTEN-IMMUNOGENIC CARRIER COMPLEX OR THE ANTIGEN, PER SE435/964, INCLUDING ENZYME-LIGAND CONJUGATE PRODUCTION (E.G., REDUCING RATE OF NONPRODUCTIVE LINKAGE, ETC.)436/543, INVOLVING PRODUCING OR TREATING ANTIGEN OR HAPTEN436/823, IMMUNOGENIC CARRIER OR CARRIER PER SE525/420, Solid polymer derived from an amino carboxylic acid or derivative; from a polyamine and a polycarboxylic acid or derivative; from at least one lactam; or from a polyamine salt of a polycarboxylic acid530/345, Chemical aftertreatment, e.g., acylation, methylation, etc.530/389.8, Binds drug, hapten, hapten-carrier complex, or specifically-identified chemical structure (e.g., theophylline, digoxin, etc.)530/405, Nitrogen containing reactant530/409, Nitrogen containing reactant530/806, ANTIGENIC PEPTIDES OR PROTEINS530/807, HAPTEN CONJUGATED WITH PEPTIDE OR PROTEIN564/346, Ether oxygen is part of the chain564/355Hydroxy, bonded directly to carbon, or ether oxygen attached directly or indirectly to the acyclic carbon or chain by acyclic nonionic bonding with no amino nitrogen between the hydroxy or ether oxygen and the aryl ring or ring system (H of -OH may be replaced by a substituted or unsubstituted ammonium ion or a Group IA or IIA light metal)ExaminersPrimary: Schain, Howard E.Attorney, Agent or FirmUS Patent References3690834, 3817837, 3852157International ClassG01N 33/531 (20060101) |
