U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Selective chemical sensitive FET transducers

Patent 4020830 Issued on May 3, 1977. Estimated Expiration Date: Icon_subject May 3, 1994. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3049118

3294988

3649505

3776819

3787309

3831432

3896008

Calcium electrode and membrane and composition for use therein Patent #: 3932233
Issued on: 01/13/1976
Inventor: Ruzicka ,   et al.

Inventors

Application

No. 05/557545 filed on 03/12/1975

US Classes:

600/348, Determining ion concentration/partial pressure204/403.1, Enzyme included in apparatus204/403.11, Glucose oxidase204/412, Three or more electrodes204/414, Gel electrolyte204/415, Selectively permeable membrane204/418, Organic membrane204/425, With impressed current means204/426, Planar electrode surface257/253, Chemical (e.g., ISFET, CHEMFET)257/414, RESPONSIVE TO NON-ELECTRICAL SIGNAL (E.G., CHEMICAL, STRESS, LIGHT, OR MAGNETIC FIELD SENSORS)257/635, Multiple layers324/425, ELECTROLYTE PROPERTIES435/287.9, Including a coated reagent or sample layer438/1, HAVING BIOMATERIAL COMPONENT OR INTEGRATED WITH LIVING ORGANISM438/49Chemically responsive

Examiners

Primary: Kaplan, G. L.

Attorney, Agent or Firm

Abstract

A chemical sensitive field-effect transistor transducer capable of selectively detecting and measuring chemical properties of substances to which the transducer is exposed. The transducer includes a semiconductor substrate material having a certain doping polarity, a pair of spaced apart diffusion regions located at the surface of the substrate material and having a doping polarity opposite that of the substrate material, electrical insulator material overlying the diffusion regions and the surface of the substrate material lying between the diffusion regions, and a chemical selective system overlying the insulator material. The chemical selective system is adapted to interact with certain substances and thereby modulate an electric field produced in the substrate material between the diffusion regions. This modulation is dependent upon the chemical properties of the substances and provides a measure of those chemical properties. The chemical selective system may include various structures for measuring ion activity, immunochemical concentrations, reducible gas concentrations and the concentrations of enzymes and substrates.

Other References

  • P Bergveld, IEEE Trans. on Bio-Med. Eng., pp. 70-71, Jan. 1970
  • Tadayuki Matsuo et al., IEEE Trans. on Bio-Med. Eng., pp. 485-487, Nov. 1974
  • Piet Bergveld, IEEE Trans. on Bio-Med. Eng., vol. BME-19, No. 5, pp. 342-351, Sept. 1972
  • Gary R. Rechnitz, C & EN, pp. 29-35, Jan. 27, 1975
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