Calcium electrode and membrane and composition for use therein Patent #: 3932233
ApplicationNo. 05/557545 filed on 03/12/1975
US Classes:600/348, Determining ion concentration/partial pressure204/403.1, Enzyme included in apparatus204/403.11, Glucose oxidase204/412, Three or more electrodes204/414, Gel electrolyte204/415, Selectively permeable membrane204/418, Organic membrane204/425, With impressed current means204/426, Planar electrode surface257/253, Chemical (e.g., ISFET, CHEMFET)257/414, RESPONSIVE TO NON-ELECTRICAL SIGNAL (E.G., CHEMICAL, STRESS, LIGHT, OR MAGNETIC FIELD SENSORS)257/635, Multiple layers324/425, ELECTROLYTE PROPERTIES435/287.9, Including a coated reagent or sample layer438/1, HAVING BIOMATERIAL COMPONENT OR INTEGRATED WITH LIVING ORGANISM438/49Chemically responsive
ExaminersPrimary: Kaplan, G. L.
Attorney, Agent or Firm
AbstractA chemical sensitive field-effect transistor transducer capable of selectively detecting and measuring chemical properties of substances to which the transducer is exposed. The transducer includes a semiconductor substrate material having a certain doping polarity, a pair of spaced apart diffusion regions located at the surface of the substrate material and having a doping polarity opposite that of the substrate material, electrical insulator material overlying the diffusion regions and the surface of the substrate material lying between the diffusion regions, and a chemical selective system overlying the insulator material. The chemical selective system is adapted to interact with certain substances and thereby modulate an electric field produced in the substrate material between the diffusion regions. This modulation is dependent upon the chemical properties of the substances and provides a measure of those chemical properties. The chemical selective system may include various structures for measuring ion activity, immunochemical concentrations, reducible gas concentrations and the concentrations of enzymes and substrates.