Method and therapeutic system for treating aqueous deficient dry eye
Patent 3991759 Issued on November 16, 1976. Estimated Expiration Date: 
November 16, 1993. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
November 16, 1993. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3664340 3811444 3818909 3828777 3832458 3896819 3917119 InventorApplicationNo. 625918 filed on 10/28/1975US Classes:424/427, Ocular604/521Therapeutic material to facilitate ocular treatmentExaminersPrimary: Medbery, Aldrich F.Attorney, Agent or FirmAbstractMethod for treating aqueous deficient dry eye by instilling a biologically compatible solute, such as sodium chloride, into the tear film continuously at a controlled rate that is sufficient to osmotically induce a continuous flow of water from the interstitial fluid to the tear film and thereby correct the aqueous deficiency. The method may be carried out by placing a therapeutic system, in the form of an ocular insert, into the cul-de-sac, the insert comprising the solute confined within a polymer matrix that releases the solute continuously at 3 to 20 micromoles of solute species per hour.Other References
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