U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Stabilization of internally administered pancreatic lipase

Patent 3991180 Issued on November 9, 1976. Estimated Expiration Date: Icon_subject November 9, 1993. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.

Patent References

3081225

3256150

Inventors

Assignee

Application

No. 512743 filed on 10/07/1974

US Classes:

424/94.6, Hydrolases (3. ) (e.g., urease, lipase, asparaginase, muramidase, etc.)424/477Containing proteins or derivatives thereof

Examiners

Primary: Rosen, Sam

Attorney, Agent or Firm

Abstract

A method for treating exocrine pancreatic insufficiency is disclosed. The method comprises the administration of a stable solid medicinal preparation containing finely particulated lipase intimately admixed with Hammarsten's casein and a tabletting lubricant, whereby a hydraulic pressure of about 2000 to about 5000 psi is employed.

Other References

  • Downey et al., Chem. Abstr., vol. 72 (1970) p. 118050f
  • Shani et al., Arch. Biochem. & Biophysics, vol. III (1965) pp. 257-263
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