Effervescent enteric coated L-dopa formulation and method of using the same
Patent 3961041 Issued on June 1, 1976. Estimated Expiration Date: 
June 1, 1993. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.
June 1, 1993. Estimated Expiration Date is calculated based on simple USPTO term provisions. It does not account for terminal disclaimers, term adjustments, failure to pay maintenance fees, or other factors which might affect the term of a patent.Patent References 3131123 3891696 InventorsAssigneeApplicationNo. 566745 filed on 04/10/1975US Classes:424/466, Effervescent424/44, Gas produced in situ by chemical reaction514/649Amino nitrogen attached to aryl ring or aryl ring system by an acyclic carbon or acyclic chainExaminersPrimary: Rose, Shep K.Attorney, Agent or FirmForeign Application Priority Data1974-11-14 JAAbstractTherapeutic levels of L-DOPA are achieved by orally administering a pharmaceutical effervescent-enteric coated tablet comprising:A. a member selected from the group consisting of L-DOPA or a derivative thereof capable of enzymatically cleaving and reverting to L-DOPA in vivo,B. a non-toxic pharmaceutically acceptable inert diluent,C. a non-toxic pharmaceutically acceptable carbon dioxide releasing agent,D. a non-toxic pharmaceutically acceptable effervescing agent, andE. a non-toxic pharmaceutically acceptable enteric coating.This composition is extremely useful in the treatment of Parkinsonism. When administered to warm-blooded animals (e.g., humans), superior therapeutic blood levels of L-DOPA are observed over that normally observed with conventional enteric coated formulations.Other References
Field of SearchGas produced in situ by chemical reaction | |
