ApplicationNo. 409346 filed on 10/24/1973
US Classes:544/317, The nitrogen is bonded directly at 4- or 6-position544/295, Plural diazine rings544/312, 5-position is unsubstituted or alkyl substituted only544/314, Additional chalcogen attached directly or indirectly to the diazine ring by nonionic bonding544/318Additional chalcogen attached directly or indirectly to the diazine ring by nonionic bonding
ExaminersPrimary: Meyers, Albert T.
Assistant: Schenkman, Leonard
Attorney, Agent or Firm
Abstract(2-Pyrimidinylthio)alkanoic acid, esters, amides and hydrazides as well as various 4- and 6-substituted derivatives thereof as depicted by the structural formula: ##SPC1##In which R and R2 are independently --H or lower alkyl; R1 is --H, -halo or lower alkoxy; Z is --OH, OM, lower alkoxy or --(NH)1 --NH2, wherein p is 0 to 1 and M is an alkali metal, alkaline earth metal or ammonium cation; Y is an aryl, amino or substituted amino radical; and m is an integer from 0 to 2, exhibit anti-lipemic activity in warm-blooded animals.