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| Number | Title | Issue Date |
| 6455042 | Method of treating ulcerative colitis or crohn's disease by administering an antibody to댞댧 integrin The present invention relates to a method for treating an autoimmune disease, such ulcerative coliteis or crohns disease characterized by lymphocyte accumulation at epithelial sites. The method involves administering to a subject an effective amount of an... | 09/24/2002 |
| 6063906 | Antibodies to integrin alpha subunit The present invention relates to antibodies that bind to a highly charged region of the integrin 댞 subunit and its functional equivalents. The antibodies are useful in screening assays to identify agents which mimic the ligand-binding si... | 05/16/2000 |
| 6057423 | Integrin alpha subunit The present invention relates to a novel integrin 댞 subunit and its functional equivalents. The method for screening a molecular library to identify lead compounds which mimick the in vivo activity of an integrin 댞 chai... | 05/02/2000 |
| 5610281 | Antibodies for modulating heterotypic E-cadherin interactions with human T lymphocytes The invention relates to methods and compositions for modulating the heterotypic adhesion between E-cadherin expressing cells and T lymphocytes. Monoclonal antibodies which specifically bind to E-cadherin and isolated peptides which mimic the binding func... | 03/11/1997 |
| 5594120 | Integrin alpha subunit The present invention relates to a novel integrin 댞 subunit and its functional equivalents. The invention further includes pharmaceutical compositions containing the isolated peptides, oligonucleotides encoding the peptides, vectors cont... | 01/14/1997 |
| 5445940 | Methods and compositions for detecting and treating a subset of human patients having an autoimmune disease Provided are monoclonal antibodies, fragments, and derivatives thereof reactive with an epitope of the T cell receptor alpha chain variable region, V.1, on human T lymphocytes. The monoclonal antibodies are reactive with approximately 2% of CD4 | 08/29/1995 |
| 5185250 | Human γ, δT cell antigen receptor polypeptides and nucleic acids The present invention is directed to purified polypeptides comprising the γ T cell antigen receptor (TCR) polypeptide, the δ TCR polypeptide, a γ, δ TCR complex, or a fragment thereof containing an epitope. The invention also relates to nucleic acid ... | 02/09/1993 |
