Inventor: Ping Zhou

Address: Plainsboro, NJ
No. of patents: 29
Last patent issue date: 04/27/2010

Number	Title	Issue Date
7705030	Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and ...	04/27/2010
7700602	Amino-5,5-diphenylimidazolone derivatives for the inhibition of β-secretase The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated β-amyloid deposits or β-amyloid levels in a patient.	04/20/2010
7541358	1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	06/02/2009
7488832	Azolylacylguanidines as β-secretase inhibitors The present invention provides an azolylacylquanidine compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tang...	02/10/2009
7482349	Amino-5,5-diphenylimidazolone derivatives for the inhibition of β-secretase The present invention provides a compound of formula I and the use thereof for the therapeutic treatment, prevention or amelioration of a disease or disorder characterized by elevated β-amyloid deposits or β-amyloid levels in a patient.	01/27/2009
7452885	Amino-5-(6-membered)heteroarylimidazolone compounds and the use thereof for β-secretase modulation The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and ...	11/18/2008
7417047	Amino-5-(5-membered)hetero-arylimidazolone compounds and the use thereof for β-secretase modulation The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and ...	08/26/2008
7271180	1-Aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor ...	09/18/2007
7022701	Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	04/04/2006
6919354	1-aryl-or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor ...	07/19/2005
6903112	Heterocyclylindazole and -azaindazole compounds as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor. ...	06/07/2005
6831094	Heterocyclylalkoxy-,-alkylthio-and -alkylaminobenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	12/14/2004
6815456	Heterocyclyloxy-, -thioxy- and -aminobenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	11/09/2004
6770642	Indolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	08/03/2004
6767912	Heterocyclylindazole and -azaindazole compounds as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor. ...	07/27/2004
6727270	Pyrrolylalkylidene-hydrazinecarboximidamide derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	04/27/2004
6727246	1-(aminoalkyl)-3-sulfonylindole-and-indazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides compounds of formula I and the use thereof for the treatment of central nervous system disorders related to or affected by the 5-HT6 receptor. ...	04/27/2004
6710069	1-aryl- or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	03/23/2004
6613781	Heterocyclylaklylindole or -azaindole compounds as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof in the therapeutic treatment of disorders related to or affected by the 5-HT6 receptor ##STR1##...	09/02/2003
6610712	Aryloxy piperidinyl derivatives for the treatment of depression This invention provides compounds useful in treating serotonin-related central nervous system disorders, including anxiety, generalized anxiety disorder, panic disorder, obsessive-compulsive disorder, sleep disorders, sexual dysfunction, alcohol and drug ...	08/26/2003
6509357	1-aryl or 1-alkylsulfonylbenzazole derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ##STR1##...	01/21/2003
6489342	Aryloxy piperidinyl indoles for treating depression This invention provides aryloxy indole derivatives which are useful for the treatment of diseases affected by disorders of the serotonin-affected neurological systems, such as depression and anxiety, the compounds having the formula: ##STR1## wherein...	12/03/2002
6465482	Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise ##STR1## Wherein: R1, R2 and R3 are each, independently, hydrogen, halogen, CF3, alkyl, alkox...	10/15/2002
6313126	Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which comprise ##STR1## Wherein: R1, R2 and R3 are each, independently, hydrogen, halogen, CF3, alkyl, alkox...	11/06/2001
6162803	Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression Compounds effective in treating disorders of the serotonin-affected neurological symptoms are provided, such compounds having the following formula: ##STR1## wherein: R1 and R5 are each, independently, hydrogen, halogen, lo...	12/19/2000
6110956	N-aryloxyethylamine derivatives for the treatment of depression Compounds effective in treating disorders of the serotonin-affected neurological systems are provided, such compounds having the following formula: ##STR1## wherein: R1 and R2 are each, independently, hydrogen, halogen, CF	08/29/2000
6054582	Process for pyrimidinone compounds This invention relates to a process for the preparation of pyrimidinone compounds of the formula ##STR1## wherein Ar is an optionally substituted aryl or heteroaromatic moiety, R3 is an optionally substituted alkyl, alkenyl or alkynyl, R5	04/25/2000
6051710	Process for pyrimidinone compounds This invention relates to a process for the preparation of pyrimidinone compounds of the formula ##STR1## wherein Ar is an optionally substituted aryl or heteroaromatic moiety, R3 is an optionally substituted alkyl, alkenyl or alkynyl, R5	04/18/2000
5889184	Process for pyrimidinone compounds This invention relates to a process for the preparation of pyrimidinone compounds of the formula ##STR1## wherein Ar is an optionally substituted aryl or heteroaromatic moiety, R3 is an optionally substituted alkyl, alkenyl or alkynyl, R5	03/30/1999

PatentStorm

Bizarre Patents

PatentStorm News

Inventor: Ping Zhou