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| Number | Title | Issue Date |
| 8153664 | Bicyclic and tricyclic derivatives as thrombin receptor antagonists Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein represents an optional double bond,... | 04/10/2012 |
| 8148363 | Heterocyclic compounds as factor IXA inhibitors The present invention relates to novel heterocyclic compounds of Formulae I-III; as disclosed herein or a pharmaceutically acceptable salt, solvate, ester, prodrug or stereoisomer thereof. Also disclosed are pharmaceutical compositions comprising said compounds, and... | 04/03/2012 |
| 8022088 | Substituted bicyclic and tricyclic thrombin receptor antagonists Substituted bicyclic and tricyclic modified himbacine derivative of the formula: or a pharmaceutically acceptable salt or solvate of said compound wherein represents an optional double bond and wherein En, F... | 09/20/2011 |
| 7897601 | Cannabinoid receptor modulators A compound having the general structure of Formula (I): or a pharmaceutically acceptable salt, solvate, or ester thereof, is useful in treating diseases, disorders, or conditions such as obesity, metabolic disorders, addict... | 03/01/2011 |
| 7888377 | Monocyclic and bicyclic himbacine derivatives useful as thrombin receptor antagonists Monocyclic and bicyclic himbacine derivatives of the formula or a pharmaceutically acceptable salt or solvate of said compound wherein represents an optional double bond and wherein G | 02/15/2011 |
| 7776889 | Spirocyclic thrombin receptor antagonists Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein represents an optional double bond,... | 08/17/2010 |
| 7713999 | Thrombin receptor antagonists Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt thereof, wherein: the dotted line represents an optional single bond; represent... | 05/11/2010 |
| 7488742 | Thrombin receptor antagonists A series of compounds represented by the structural formulas and pharmaceutically acceptable isomers, salts, solvates and polymorphs thereof are disclosed. Also disclosed are pharmaceutical composi... | 02/10/2009 |
| 7488752 | Thrombin receptor antagonists Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salt or solvate of said compound, isomer or racemic mixture wherein z,1 represents an optional double bond, the dotted line is optionally a... | 02/10/2009 |
| 7442712 | Constrained himbacine analogs as thrombin receptor antagonists A compound represented by the structural formula and pharmaceutically acceptable salts and solvents thereof is disclosed, wherein: the single-dashed line | 10/28/2008 |
| 7037920 | Substituted tricyclic himbacine derivatives that are useful as thrombin receptor antagonists Heterocyclic-substituted tricyclics of the formula or a pharmaceutically acceptable salts thereof, wherein: n1 and n2 are independently 0-2; Het... | 05/02/2006 |
| 6894065 | Thrombin receptor antagonists Heterocyclic-substituted compounds of the formula or a pharmaceutically acceptable salt thereof, are disclosed, wherein: Z is —(CH2)n—; | 05/17/2005 |
| 6645987 | Nor-seco himbacine derivatives useful as thrombin receptor antagonists Heterocyclic-substituted compounds of the formula ##STR1## or a pharmaceutically acceptable salt thereof, are disclosed.... | 11/11/2003 |
