...that after Walter Hunt patented the safety pin in 1849, he sold the rights to it for $400?
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| Number | Title | Issue Date |
| 7869014 | System for measuring the wavelength dispersion and nonlinear coefficient of an optical fiber A method of simultaneously specifying the wavelength dispersion and nonlinear coefficient of an optical fiber. Pulsed probe light and pulsed pump light are first caused to enter an optical fiber to be measured. Then, the power oscillation of the back-scattered light... | 01/11/2011 |
| 7586091 | Mass spectrometric system and mass spectrometry After a sample is previously separated into plural components in a channel formed in a microchip (353), the channel is irradiated along a separation direction with a laser beam from a laser oscillator (361) to sequentially ionize each fraction separate... | 09/08/2009 |
| 7424191 | System for measuring the wavelength dispersion and nonlinear coefficient of an optical fiber A method of simultaneously specifying the wavelength dispersion and nonlinear coefficient of an optical fiber. Pulsed probe light and pulsed pump light are first caused to enter an optical fiber to be measured. Then, the power oscillation of the back-scattered light... | 09/09/2008 |
| 7146085 | Method and system for measuring the wavelength dispersion and nonlinear coefficient of an optical fiber, method of manufacturing optical fibers, method of measuring wavelength-dispersion distribution, method of compensating for measurement errors, and method of specifying conditions of measurement A method of simultaneously specifying the wavelength dispersion and nonlinear coefficient of an optical fiber. Pulsed probe light and pulsed pump light are first caused to enter an optical fiber to be measured. Then, the power oscillation of the back-scattered light... | 12/05/2006 |
| 7003202 | Method and system for measuring the wavelength dispersion and nonlinear coefficient of an optical fiber, method of manufacturing optical fibers, method of measuring wavelength-dispersion distribution, method of compensating for measurement errors, and method of specifying conditions of measurement A method of simultaneously specifying the wavelength dispersion and nonlinear coefficient of an optical fiber. Pulsed probe light and pulsed pump light are first caused to enter an optical fiber to be measured. Then, the power oscillation of the back-scattered light... | 02/21/2006 |
| 5747502 | Process for preparing benzoc!phenanthridinium derivatives, novel compounds prepared by said process, and antitumor agents The present invention relates to benzoc!phenanthridinium derivative of the general formula A: ##STR1## wherein M and N individually represent a hydroxyl or lower alkoxy group, or M and N simultaneously represent a hydrogen atom or together form a ... | 05/05/1998 |
| 5214048 | Oxetanocins This invention relates to novel oxetanocins represented by the following general formula (I): ##STR1## wherein R represents a group represented by ##STR2## and their pharmacologically acceptable salts which have antiviral activities.... | 05/25/1993 |
| 5179084 | Antiviral phosphoric acid esters of oxetanocins The present invention relates to phosphoric acid esters of oxetanocins having an antiviral activity which are represented by general formula (I): ##STR1## wherein R1 represents a phosphoric acid ester residue, X represents hydrogen, hydrox... | 01/12/1993 |
| 5128493 | Platinum complexes A diamine platinum (II) complex represented by the general formula ##STR1## [wherein R1 and R2 are each a lower alkyl group; and two X's are each a halogen atom or jointly form a group represented by ##STR2## (wherein R | 07/07/1992 |
| 5068376 | Novel platinum complexes A diamine platinum (II) complex represented by the general formula ##STR1## wherein R1, R2, R3 and R4 are each a hydrogen atom or a lower alkyl group; and two X's are each a halogen atom or jointly form a g... | 11/26/1991 |
| 5041447 | Oxetanocin-related compounds and pharmaceutical compositions containing them This invention relates to oxetanocin-related compounds represented by the following formula (I): ##STR1## [in formula (I), R1, Y and B have the following meanings: (a) R1 represents --CH2 OH or --CH2 OCO-(a... | 08/20/1991 |
| 4987246 | Novel platinum complexes A diamine platinum (II) complex represented by the general formula ##STR1## [wherein R1 and R2 are each a lower alkyl group; and two X's are each a halogen atom or jointly form a group represented by ##STR2## (wherein R | 01/22/1991 |
| 4956504 | Novel spergualin-related compounds and process for producing the same The present invention relates to novel Spergualin-related compounds represented by the general formula [I] ##STR1## (wherein X is ##STR2## R is --H or --CH2 OH; R1 is --H, ##STR3## R2 is a residue obtai... | 09/11/1990 |
| 4921984 | Novel platinum complexes A diamine platinum (II) complex represented by the general formula ##STR1## [wherein R1, R2, R3 and R4 are each a hydrogen atom or a lower alkyl group; and two X's are each a halogen atom or jointly form a ... | 05/01/1990 |
| 4864043 | Platinum complexes A diamine platinum (II) complex represented by the general formula ##STR1## [wherein R1, R2, R3 and R4 are each a hydrogen atom or a lower alkyl group; and two X's are each a halogen atom or jointly form a ... | 09/05/1989 |
| 4861905 | Platinum complexes A diamine platinum (II) complex represented by the general formula ##STR1## [wherein R1 and R2 are each a lower alkyl group; and two X's are each a halogen atom or jointly form a group represented by ##STR2## (wherein R | 08/29/1989 |
| 4824955 | Selenium oxy chloride-pyridine or bipyridine complexes This invention relates to the novel selenium compounds which are useful as an antineoplastic agent. The compounds are represented by the general formula (I): wherein R, X, A and Y represent the groups specified below, a represents a number of 0 or 1, b re... | 04/25/1989 |
| 4808703 | Novel 3-(4'-aminobutylamino) propylaminobleomycin derivatives Disclosed is a 3-(4'-aminobutylamino) propylaminobleomycin having low pulmonary toxicity, which expressed by the following general formula wherein [BX] represents a residue remaining after removing a hydroxyl group from the carboxyl group of bleomycinic acid, ... | 02/28/1989 |
| 4737589 | Platinum Complexes A diamine platinum (II) complex represented by the general formula ##STR1## [wherein R1, R2, R3 and R4 are each a hydrogen atom or a lower alkyl group; and two X's are each a halogen atom or jointly form a ... | 04/12/1988 |
| 4607114 | Novel platinum complexes This invention relates to a novel platinum-diamine complexes represented by the general formula: ##STR1## wherein R1 and R2 each represents a lower alkyl group having 1 to 3 carbon atoms or jointly represent an alkylene group ha... | 08/19/1986 |
| 4568490 | Aminopropylaminobleomycin derivatives and process for preparation thereof An aminopropylaminobleomycin represented by the following formula or a salt thereof, which is minimized in side effects such as pulmonary toxicity: wherein [BX] represents the acyl group of bleomycinic acid whose formula differs from that of bleomycin acid by ... | 02/04/1986 |
| 4556735 | Spergualin-related compounds having a phenylene group as well as a process for producing the same The invention relates to Spergualin-related compounds of the formula: ##STR1## (wherein R1 is a lower alkylene group which may be substituted by a hydroxymethyl group; X is a hydrogen atom or a halogen atom; m and n are each 0 or an intege... | 12/03/1985 |
| 4537880 | Aminopropylaminobleomycin derivatives and process for preparation thereof An aminopropylaminobleomycin represented by the following formula or a salt thereof, which is minimized in side effects such as pulmonary toxicity: wherein [BX] represents the acyl group of bleomycinic acid whose formula differs from that of bleomycin acid by ... | 08/27/1985 |
| 4529549 | Spergualin-related compounds and process for the preparation thereof This invention relates to a novel spergualin-related compound and a process for the production thereof. The novel compound, which has a high antitumor activity, is represented by the general formula ##STR1## wherein R1 represents a hydroge... | 07/16/1985 |
| 4500452 | (Amido)N-substituted bleomycins, salts thereof and process for preparation thereof A promising carcinostatic (amido)N-substituted bleomycin represented by the following formula, or a salt thereof and a process for the preparation thereof: ##STR1## wherein BM represents a moiety of bleomycin skeleton; X represents an alkyl of 1... | 02/19/1985 |
| 4472304 | (Amido)N-substituted bleomycins, salts thereof and process for preparation thereof A promising carcinostatic (amido)N-substituted bleomycin represented by the following formula, or a salt thereof and a process for the preparation thereof: ##STR1## wherein BM represents a moiety of bleomycin skeleton; X represents an alkyl of 1... | 09/18/1984 |
| 4327081 | Method of enhancing absorption of antitumor agent into gastro-intestinal tumor site and orally administrable antitumor compositions therefor This invention relates to a method for selectively enhancing absorption of 5-fluorouracil, bleomycins or bleomycin derivatives into the gastrointestinal tumor site by orally administering such substance together with an alkali metal salt of polyacrylic ac... | 04/27/1982 |
| 4273761 | Method of enhancing absorption of antitumor agent into gastrointestinal tumor site and orally administrable antitumor compositions therefor This invention relates to a method for selectively enhancing absorption of 5-fluorouracil, bleomycins or bleomycin derivatives into the gastrointestinal tumor site by orally administering such substance together with an alkali metal salt of polyacrylic ac... | 06/16/1981 |