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Inventor: Jiri G. Safar


Address: Walnut Creek, CA
No. of patents: 7
Last patent issue date: 01/16/2007

NumberTitleIssue Date
7163798Method of preparing cow brain homogenate
An assay method is disclosed which isolates and detects the presence of a disease related conformation of a protein (e.g., PrPSc) present in a sample also containing the non-disease related conformation of the protein (e.g., PrPC). The sample i...
01/16/2007
7151000Method of concentrating proteins from serum
A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain serum. The ...
12/19/2006
7094553Antibodies specific for ungulate PrP
The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrPC and/or a denatured ungulate PrPSc, but not to a native ungulate PrPSc. Preferred antibodies find native...
08/22/2006
7087213Method of preparing cow brain homogenate
A method of isolating and detecting the presence of a disease related conformation of a protein (e.g., PrPSc) is disclosed. The sample is treated such as by contacting it with a protease and then contacting the treated sample with a binding partner which ...
08/08/2006
6916419Device for removal of prions from blood, plasma and other liquids
Devices such as flow through columns, substrates such as spherical polymer beads, and methods of using such to remove prions from any liquid sample are disclosed. A surface of a substrate is coated with a prion complexing agent, such as a salt of phosphotungstic aci...
07/12/2005
6875577Method of preparing cow brain homogenate
An assay method is disclosed which isolates and detects the presence of a disease related conformation of a protein (e.g., PrPSc) present in a sample also containing the non-disease related conformation of the protein (e.g., PrPC). The sample i...
04/05/2005
6677125Assay for disease related conformation of a protein and isolating same
An assay method is disclosed which isolates and detects the presence of a disease related conformation of a protein (e.g., PrPSc) present in a sample also containing the non-disease related conformation of the protein (e.g., PrPC). T...
01/13/2004
 
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