Inventor: Francis J. Dumont

Address: Rahway, NJ
No. of patents: 3
Last patent issue date: 08/30/1994

Number	Title	Issue Date
5342935	Antagonists of immunosuppressive macrolides Hydroxymacrolides and derivatives of the general structural Formula I: ##STR1## have been prepared from suitable precursors by oxidation at C-20. These macrolides are useful as antagonists of FK-506-type immunosuppressants. The compounds of the prese...	08/30/1994
5190950	Antagonists of immunosuppressive macrolides A method for the modification of treatment of an immuno regulatory disorder or disease with an FK-506-type immunosuppressive macrolide comprising the administration to a mammalian species in need of such modification of an effective amount of a compound o...	03/02/1993
4914188	Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin Novel cyclosporin analogs containing a MeAla or MeAbu residue at the 6-position of the cyclic undecapeptide have been synthesized and found unexpectedly to exhibit antagonistic activity toward cyclosporin A binding to its cytosolic protein receptor, cyclo...	04/03/1990

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