Did You Know...
...that in 1800 ether was first used by partyers as a fun diversion? Sniffing the gas led to hilarious and raucous laughter as people watched each other become more and more intoxicated and silly. Several doctors independently realized the value ether would have to anesthetize surgery patients. Of those who claimed rights to the "discovery," none had a happy ending. One had a seizure and died defending his rights. Another spent his life in an asylum because he had been denied acclaim. A third became addicted to chloroform and, in a New York City jail, he soaked a cloth in the drug, severed an artery and bled to death.
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| Number | Title | Issue Date |
| 7875703 | LIR-9, a novel leukocyte immunoglobulin-like receptor A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined nucleotide... | 01/25/2011 |
| 7863019 | Interleukin-15 receptors There are disclosed Interleukin-15 Receptor (IL-15R) proteins, DNAs and expression vectors encoding IL-15R, and processes for producing IL-15R as products of recombinant cell cultures. ... | 01/04/2011 |
| 7625553 | Method of treating cancer by administering an epithelum-derived T-cell factor Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating o... | 12/01/2009 |
| 7411050 | Monoclonal blocking antibody to human RANKL Disclosed herein are kits for detecting RANKL protein or nucleic acids, the kits comprising isolated human RANKL polypeptides, RANKL nucleic acids and/or antibodies specific for RANKL. ... | 08/12/2008 |
| 7411055 | Attractin/mahogany-like polypeptides, polynucleotides, antibodies and methods of use thereof The present disclosure provides attractin/mahogany-like polypeptides and fragments thereof, polynucleotides encoding such polypeptides and fragments, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides ... | 08/12/2008 |
| 7323558 | Nucleic acids encoding dendritic cell transmembrane serine protease Isolated Dendritic Cell Transmembrane Serine Proteases (DCTSPs), DNAs encoding such DCTSPs, and pharmaceutical and/or diagnostic compositions made therefrom, are disclosed. The isolated DCTSPs can be used to hydrolyze peptide bonds. The DCTSPs are also useful in scr... | 01/29/2008 |
| 7262274 | Kits containing rank polypeptides Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are also useful in screening for inhibitors thereof. ... | 08/28/2007 |
| 7192935 | Polynucleotides encoding epithelium-derived T-cell factor and uses thereof Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for treating o... | 03/20/2007 |
| 7183380 | Human ataxin-1-like polypeptide IMX97018 This invention relates to IMX97018, a new members of the human ataxin-1-like polypeptide family, methods of making such polypeptides, and to methods of using them to diagnose and treat neurological conditions and to identify compounds that alter IMX97018 polypeptide... | 02/27/2007 |
| 7041782 | Lectin ss3939 DNA and polypeptides The invention is directed to purified and isolated novel ss3939 polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmented peptides deriv... | 05/09/2006 |
| 7001752 | Murine and human kinases The inventions is directed to purified and isolated novel murine and human kinase polypeptides, the nucleic acid encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragment... | 02/21/2006 |
| 6913893 | IL-1/TNF-α-activated kinase (ITAK), and methods of making and using the same Purified and isolated IL-1/TNF-α-activated kinase (ITAK), nucleic acids encoding ITAK, processes for production of recombinant forms of ITAK, pharmaceutical compositions containing ITAK, and use of ITAK in therapies and in various assays, including assays to detect... | 07/05/2005 |
| 6887687 | Nucleic acids encoding human ataxin-1-like polypeptide IMX97018 This invention relates to IMX97018, a new members of the human ataxin-1-like polypeptide family, methods of making such polypeptides, and to methods of using them to diagnose and treat neurological conditions and to identify compounds that alter IMX97018 polypeptide... | 05/03/2005 |
| 6867013 | Methods of screening for antagonists and agonists of polypeptides having kinase functions The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragmente... | 03/15/2005 |
| 6838262 | Isolated DNA molecule encoding rank ligand Isolated ligands, DNAs encoding such ligands, and pharmaceutical compositions made therefrom, are disclosed. The isolated ligands can be used to regulate an immune response. The ligands are also useful in screening for inhibitors thereof. ... | 01/04/2005 |
| 6794173 | Dendritic cell transmembrane serine protease Isolated Dendritic Cell Transmembrane Serine Proteases (DCTSPs), DNAs encoding such DCTSPs, and pharmaceutical and/or diagnostic compositions made therefrom, are disclosed. The isolated DCTSPs can be used to hydrolyze peptide bonds. The DCTSPs are also useful in scr... | 09/21/2004 |
| 6764836 | Interleukin-15 receptors There are disclosed Interleukin-15 Receptor (IL-15R) proteins, DNAs and expression vectors encoding IL-15R, and processes for producing IL-15R as products of recombinant cell cultures. ... | 07/20/2004 |
| 6759223 | Calcium/calmodulin-dependent kinase The invention is directed to purified and isolated novel murine and human kinase polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides, fragment... | 07/06/2004 |
| 6740522 | Antibodies against ligand for receptor activator of NF-kB Provided herein are antibodies that bind human RANKL polypeptides. ... | 05/25/2004 |
| 6562948 | Receptor activator of NF-.kappa.B Provided herein are isolated antibodies that specifically bind a RANK polypeptide.... | 05/13/2003 |
| 6548065 | Interleukin-15 receptors There are disclosed Interleukin-15 Receptor (IL-15R) proteins, DNAs and expression vectors encoding IL-15R, and processes for producing IL-15R as products of recombinant cell cultures.... | 04/15/2003 |
| 6541232 | Polypeptides having kinase activity Purified and isolated IL-1/TNF--activated kinase (ITAK), nucleic acids encoding ITAK, processes for production of recombinant forms of ITAK, pharmaceutical compositions containing ITAK, and use of ITAK in therapies and in various assays, including ... | 04/01/2003 |
| 6537763 | Receptor activator of NF-.kappa.B Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are also useful in screening for inhibitors thereof.... | 03/25/2003 |
| 6528482 | Receptor activator of NF-.kappa.B Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are also useful in screening for inhibitors thereof.... | 03/04/2003 |
| 6514719 | Methods for identifying compounds that alter kinase activity The invention is directed to purified and isolated novel murine and human kinase polypeptides, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptide... | 02/04/2003 |
| 6479635 | Receptor activator of NF-.kappa.B Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are also useful in screening for inhibitors thereof.... | 11/12/2002 |
| 6419929 | Recombinant RANK-L polypeptide Isolated recombinant RANK-L polypeptide DNAs encoding RANK-L polypeptide, and pharmaceutical compositions made therefrom, are disclosed. The isolated RANK-L polypeptide can be used to regulate an immune response. The RANK-L polypeptide is also useful in s... | 07/16/2002 |
| 6387676 | Human cDNAs encoding polypeptides having kinase functions The invention is directed to purified and isolated human polypeptides having kinase function, the nucleic acids encoding such polypeptides, processes for production of recombinant forms of such polypeptides, antibodies generated against these polypeptides... | 05/14/2002 |
| 6384203 | Family of immunoregulators designated leukocyte immunoglobulin-like receptors (LIR) A new family of immunoreceptor molecules of the immunoglobulin superfamily, (LIR) polypeptides is described. Disclosed are sequences encoding LIR family members and their deduced amino acid sequences, polypeptides encoded by DNA that hybridizes to defined... | 05/07/2002 |
| 6242213 | Isolated DNA molecules encoding RANK-L Isolated ligands, DNAs encoding such ligands, and pharmaceutical compositions made therefrom, are disclosed. The isolated ligands can be used to regulate an immune response. The ligands are also useful in screening for inhibitors thereof.... | 06/05/2001 |
| 6184359 | Antibodies to epithelium-derived T-cell factor Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for... | 02/06/2001 |
| 6080557 | IL-1/TNF--activated kinase (ITAK), and methods of making and using the same Purified and isolated IL-1/TNF--activated kinase (ITAK), nucleic acids encoding ITAK, processes for production of recombinant forms of ITAK, pharmaceutical compositions containing ITAK, and use of ITAK in therapies and in various assays, including ... | 06/27/2000 |
| 6017729 | Receptor activator of NF-.kappa.B Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are also useful in screening for inhibitors thereof.... | 01/25/2000 |
| 5985262 | Method of treatment with epithelium derived T-cell factor Nucleic acid sequences which encode biologically active EMF, expression vectors which direct the expression of ETF, ETE polypeptides, antibodies which specffically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for... | 11/16/1999 |
| 5892001 | Epithelium-derived T-cell factor antibodies Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for... | 04/06/1999 |
| 5707616 | Method for treating or preventing gastrointestinal disease with epithelium-derived T-cell factor Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for... | 01/13/1998 |
| 5591630 | Monoclonal antibodies that bind interleukin-15 receptors There are disclosed Interleukin-15 Receptor (IL-15R) proteins, DNAs and expression vectors encoding IL-15R, and processes for producing IL-15R as products of recombinant cell cultures. Also disclosed are monoclonal antibodies that bind Interleukin-15 rece... | 01/07/1997 |
| 5574138 | Epithelium-derived T-cell factor Nucleic acid sequences which encode biologically active ETF, expression vectors which direct the expression of ETF, ETF polypeptides, antibodies which specifically bind ETF and processes for preparing the same are disclosed. Also disclosed are methods for... | 11/12/1996 |
| 4882282 | DNA sequences encoding bovine interleukin-2 A chemically-synthesized oligonucleotide composing a portion of the nucleotide sequence of the human IL-2 is employed as a probe to isolate the gene coding for human IL-2. The human IL-2 gene is selected from a cDNA library prepared from RNA produced by m... | 11/21/1989 |
