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| Number | Title | Issue Date |
| 8236574 | Ultra-sensitive detection of molecules or particles using beads or other capture objects The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may ... | 08/07/2012 |
| 8222047 | Ultra-sensitive detection of molecules on single molecule arrays The present invention relates to systems and methods for detecting analyte molecules or particles in a fluid sample and in some cases, determining a measure of the concentration of the molecules or particles in the fluid sample. Methods of the present invention may ... | 07/17/2012 |
| 8189191 | Spectroscopic imaging microscopy Disclosed herein are systems that include: (a) an objective lens system configured to collect light from a sample; (b) a first aperture positioned to allow a portion of the collected light received from the objective lens system to pass as input light; (c) a first l... | 05/29/2012 |
| 7754498 | Self-encoding sensor with microspheres A microsphere-based analytic chemistry system is disclosed in which self-encoding microspheres having distinct characteristic optical response signatures to specific target analytes may be mixed together while the ability is retained to identify the sensor type and ... | 07/13/2010 |
| 7622294 | Methods for detecting target analytes and enzymatic reactions A microsphere-based analytic chemistry system and method for making the same is disclosed in which microspheres or particles carrying bioactive agents may be combined randomly or in ordered fashion and dispersed on a substrate to form an array while maintaining the ... | 11/24/2009 |
| 7595473 | Method and system of array imaging The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array by minimizing the effects of photobleaching. The imaging system has a light source, a variable exposure aperture, and a variable filter ... | 09/29/2009 |
| 6999657 | High density optical data storage A data storage apparatus includes an array of optical fibers. The array has a first end and a second end. The first end of the array includes multiple optical fiber ends, each optical fiber end having an end face adapted for receiving light of a wavelength λ into t... | 02/14/2006 |
