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Inventor: Ching-Juh Lai


Address: Bethesda, MD
No. of patents: 7
Last patent issue date: 12/25/2012

NumberTitleIssue Date
8337853Monoclonal antibodies that bind or neutralize dengue virus
The present invention relates to monoclonal antibodies that bind or neutralize dengue type 1, 2, 3, and/or 4 virus. The invention provides such antibodies, fragments of such antibodies retaining dengue virus-binding ability, fully human or humanized antibodies retai...
12/25/2012
8337854Monoclonal antibodies against dengue and other viruses with deletion in Fc region
The present invention relates to a variant of a parent polypeptide comprising an Fc region, which variant binds an Fc gamma receptor (FcγR) with lower affinity than the parent polypeptide and comprises a deletion of at least one amino acid in about position 100 to ...
12/25/2012
7622113Monoclonal antibodies that bind or neutralize dengue virus
The present invention relates to monoclonal antibodies that bind or neutralize dengue type 1, 2, 3, and/or 4 virus. The invention provides such antibodies, fragments of such antibodies retaining dengue virus-binding ability, fully human or humanized antibodies retai...
11/24/2009
6676936Chimeric and/or growth-restricted flaviviruses
The invention includes a chimeric virus for use in a vaccine preparation having a genome comprising nucleic acid sequences encoding at least one structural protein from one flavivirus and nucleic acid sequences encoding nonstructural protein from another ...
01/13/2004
6660273Chimeric vaccine against tick-borne encephalitis virus
A live, attenuated chimeric virus vaccine against tick-borne encephalitis virus comprising the preM and E structural genes of the tick-borne encephalitis Langat virus and the non-structural genes of the mosquito-borne dengue virus. The live chimeric vacci...
12/09/2003
6497884Chimeric vaccine against tick-borne encephalitis virus
A live, attenuated chimeric virus vaccine against tick-borne encephalitis virus comprising the preM and E structural genes of the tick-borne encephalitis Langat virus and the non-structural genes of the mosquito-borne dengue virus. The live chimeric vacci...
12/24/2002
6184024Chimeric and/or growth-restricted flaviviruses
The invention includes a chimeric virus for use in a vaccine preparation having a genome comprising nucleic acid sequences encoding at least one structural protein from one flavivirus and nucleic acid sequences encoding nonstructural protein from another ...
02/06/2001
 
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