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| Number | Title | Issue Date |
| 7705155 | Processes for the production of useful intermediates The present application relates to a new process for the asymmetric production of 3-(pyridin-4-yl)-3-hydroxy-pentanoic acid derivatives, which are useful intermediates in the manufacture of compounds that are known to show antiproliferative activity. ... | 04/27/2010 |
| 7135478 | Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer. ... | 11/14/2006 |
| 7053102 | Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring β-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer... | 05/30/2006 |
| 7012079 | Optically pure camptothecin analogues The invention relates in particular to the compounds of general formula in which R1, R2, R3, R4, R5, R6 represent various radicals; their use as medicame... | 03/14/2006 |
| 6815546 | Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer. ... | 11/09/2004 |
| 6797715 | Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them A method of treating a cancer in warm-blooded animals by administration to the warm-blooded animals in need thereof a camptothecin analog a 7-ring member β-hydroxy lactone ring of the formula wherein the substituents ar... | 09/28/2004 |
| 6762301 | Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them A process for the preparation of a compound of the formula wherein the substituents are defined as set forth in the specification comprising reacting a compound of the formula | 07/13/2004 |
| 6632946 | Tetracyclic analogues of camptothecins, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them The invention relates to new tetracyclic analogues of camptothecin, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them. Said analogues, which include in particular 3-hydroxy-3-(4-oxo-4,6-dihydroindoli... | 10/14/2003 |
| 6436951 | Camptothecin tetracyclic analogues, preparation, method, applications as medicines and pharmaceutical compositions containing them The invention relates to new tetracyclic analogues of camptothecin, their preparation processes, their use as medicaments and the pharmaceutical compositions containing them. Said analogues, which include in particular 3-hydroxy-3-(4-oxo-4,6-dihydroindoli... | 08/20/2002 |
| 6339091 | Comptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues The compound of the formula ##STR1## wherein the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts which are useful for the treatment of viral infections, parasitic diseases and the treatment of can... | 01/15/2002 |
| 5492906 | Derivatives of thieno-triazolo-diazepine and therapeutic compositions containing them The invention relates to thieno-triazolo-diazepine derivatives of the formula: ##STR1## wherein Y stands for oxygen or sulphur and R stands for various substituents, to a preparation process of said compounds and to therapeutic compositions cont... | 02/20/1996 |
