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| Application No. | Application Title | Issue Date |
| 20130012683 | MULTIFUNCTIONAL COMPOUNDS FOR FORMING CROSSLINKED BIOMATERIALS AND METHODS OF PREPARATION AND USE Multifunctional compounds are provided that readily crosslink in situ to provide crosslinked biomaterials. The multifunctional compounds contain a single component having at least three reactive functional groups thereon, with the functional groups selected so as to be ... | 01/10/2013 |
| 20120252905 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION Compositions are disclosed that afford drug delivery from two-part polymer compositions that rapidly form covalent linkages when mixed together. Such compositions are particularly well suited for use in a variety of tissue related applications when rapid adhesion to the... | 10/04/2012 |
| 20120052040 | POLYMER COMPOSITIONS AND METHODS FOR THEIR USE Compositions comprising anti-fibrotic agent(s) and/or polymeric compositions can be used in various medical applications including the prevention of surgical adhesions, treatment of inflammatory arthritis, treatment of scars and keloids, the treatment of vascular diseas... | 03/01/2012 |
| 20120039980 | COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE Methods of preventing adhesion between issues are provided that utilizes in situ crosslinked biomaterials. The biomaterial contains at least the crosslinked product of two biocompatible, non-immunogenic components having reactive groups thereon, with the functional grou... | 02/16/2012 |
| 20120041481 | COMPOSITIONS AND SYSTEMS FOR FORMING CROSSLINKED BIOMATERIALS AND ASSOCIATED METHODS OF PREPARATION AND USE Kits comprising dry power compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The dry powder composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups ... | 02/16/2012 |
| 20110264139 | SUTURES AND FIBROSING AGENTS Sutures are used in combination with fibrosing agents to induce or stimulate fibrosis that between the sutures and the host tissues into which the sutures are inserted. Compositions and methods are described for use in lifting tissue, closing wound, and other applicatio... | 10/27/2011 |
| 20110150821 | METHODS AND CROSSLINKED POLYMER COMPOSITIONS FOR CARTILAGE REPAIR A method of repairing damaged cartilage and soft tissue in a patient is provided using a biocompatible, non-immunogenic composition. The composition comprises a hydrophilic polymer and a plurality of crosslinkable components having reactive functional groups. The compos... | 06/23/2011 |
| 20110129513 | COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.... | 06/02/2011 |
| 20100268288 | ELECTRICAL DEVICES AND ANTI-SCARRING AGENTS Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implan... | 10/21/2010 |
| 20100222863 | SILK STENT GRAFTS Silk-containing stent grafts are provided comprising an endoluminal stent and a graft, wherein the silk induces the in vivo adhesion of the stent graft to vessel walls, or, otherwise induces or accelerates an in vivo fibrotic reaction causing said stent graft to adhere ... | 09/02/2010 |
| 20100092536 | IMPLANTABLE SENSORS AND IMPLANTABLE PUMPS AND ANTI-SCARRING AGENTS Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal.... | 04/15/2010 |
| 20100082003 | COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.... | 04/01/2010 |
| 20090280153 | electrical devices, anti-scarring agents, and therapeutic compositions Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the devices are implanted within an animal.... | 11/12/2009 |
| 20090226500 | SUTURES AND ANTI-SCARRING AGENTS Sutures are used in combination with anti-scarring agents to inhibit fibrosis between the sutures and the host tissues into which the sutures are inserted. Compositions and methods are described for use in reducing excessive scarring, surgical adhesion, and other disord... | 09/10/2009 |
| 20090214652 | SOFT TISSUE IMPLANTS AND ANTI-SCARRING AGENTS Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal.... | 08/27/2009 |
| 20090203632 | COMPOSITIONS AND METHODS FOR TREATING CONTRACTURE A method for treating contracture is provided that includes administering to a patient in need thereof a composition that includes a therapeutic agent effective in treating contracture. Compositions, devices, and kits for use in treating contracture are also described.... | 08/13/2009 |
| 20090192214 | DRUG DELIVERY FROM RAPID GELLING POLYMER COMPOSITION Compositions are disclosed that afford drug delivery from two-part polymer compositions that rapidly form covalent linkages when mixed together. Such compositions are particularly well suited for use in a variety of tissue related applications when rapid adhesion to the... | 07/30/2009 |
| 20090117070 | Methods and Crosslinked Polymer Compositions for Cartilage Repair A method of repairing damaged cartilage and soft tissue in a patient is provided using a biocompatible, non-immunogenic composition. The composition comprises a hydrophilic polymer and a plurality of crosslinkable components having reactive functional groups. The compos... | 05/07/2009 |
| 20090060973 | COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS Medical implants are provided which release a fluoropyrimidine or an analog thereof, thereby inhibiting or reducing the incidence of infection associated with the implant.... | 03/05/2009 |
| 20080312315 | Multifunctional Compounds for Forming Crosslinked Biomaterials and Methods of Preparation and Use Multifunctional compounds are provided that readily crosslink in situ to provide crosslinked biomaterials. The multifunctional compounds contain a single component having at least three reactive functional groups thereon, with the functional groups selected so as to be ... | 12/18/2008 |
| 20080241217 | COMPOSITIONS AND METHODS FOR COATING MEDICAL IMPLANTS Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.... | 10/02/2008 |
| 20080145514 | Compositions and methods for coating medical implants Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.... | 06/19/2008 |
| 20080124400 | Microparticles With High Loadings Of A Bioactive Agent The present invention discloses compositions, devices and methods for the production, use and administration of compositions that comprise microparticles that are loaded with a drug at a concentration of greater than 50% (weight drug/weight microparticle).... | 05/29/2008 |
| 20080113000 | Compositions and methods for coating medical implants Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant.... | 05/15/2008 |
| 20080089952 | Compositions and methods for coating medical implants Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant. ... | 04/17/2008 |
| 20080058579 | Compositions and methods for treating disease utilizing a combination of radioactive therapy and cell-cycle inhibitors Disclosed herein are therapeutic devices, compositions and methods for treating proliferative diseases. For example, within one aspect of the invention therapeutic devices are provided, comprising a device that locally administers radiation and a cell-cycle inhibitor ... | 03/06/2008 |
| 20080009902 | SUTURES AND FIBROSING AGENTS Sutures are used in combination with fibrosing agents to induce or stimulate fibrosis that between the sutures and the host tissues into which the sutures are inserted. Compositions and methods are described for use in lifting tissue, closing wound, and other applicatio... | 01/10/2008 |
| 20070299043 | Anti-scarring drug combinations and use thereof The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present i... | 12/27/2007 |
| 20070270447 | Compositions and methods for coating medical implants Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant. ... | 11/22/2007 |
| 20070254833 | COMPOSITIONS AND METHODS FOR TREATING DIVERTICULAR DISEASE Agents, compositions, and implants are provided herein for treating diverticular disease (e.g., diverticulosis and diverticulitis). In particular, fibrosis-inducing agents, hemostatic agents, and/or anti-infective agents, or compositions containing one or more of these ... | 11/01/2007 |
| 20070213393 | COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY CONDITIONS UTILIZING PROTEIN OR POLYSACCHARIDE CONTAINING ANTI-MICROTUBULE AGENTS Disclosed herein are compositions and methods for treating a variety of inflammatory conditions (e.g., inflammatory arthritis, adhesions, tumor excision sites, and fibroproliferative diseases of the eye). For example, there is provided a composition comprising a protein... | 09/13/2007 |
| 20070208134 | Anti-scarring drug combinations and use thereof The present invention provides devices or implants that comprise anti-scarring drug combinations, methods or making such devices or implants, and methods of inhibiting fibrosis between the devices or implants and tissue surrounding the devices or implants. The present i... | 09/06/2007 |
| 20070198063 | Electrical devices and anti-scarring drug combinations Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring drug combination or a composition that comprises an anti-scarring drug combination to inhibit scarring that may otherw... | 08/23/2007 |
| 20070196421 | Soft tissue implants and drug combination compositions, and use thereof Soft tissue implants (e.g., breast, pectoral, chin, facial, lip, and nasal implants) are used in combination with an anti-scarring drug combination in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. ... | 08/23/2007 |
| 20070197957 | Implantable sensors, implantable pumps and anti-scarring drug combinations Pumps and sensors for contact with tissue are used in combination with an anti-scarring agent or a composition that comprises an anti-scarring agent to inhibit scarring that may otherwise occur when the pumps and sensors are implanted within an animal. ... | 08/23/2007 |
| 20060282123 | Electrical devices and anti-scarring agents Electrical devices (e.g., cardiac rhythm management and neurostimulation devices) for contact with tissue are used in combination with an anti-scarring agent (e.g., a cell cycle inhibitor) in order to inhibit scarring that may otherwise occur when the devices are implan... | 12/14/2006 |
| 20060240063 | Medical implants and fibrosis-inducing agents Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue. ... | 10/26/2006 |
| 20060240064 | Medical implants and fibrosis-inducing agents Implants are used in combination with a fibrosis-inducing agent in order to induce fibrosis that may otherwise not occur when the implant is placed within an animal or increase fibrosis between the implant and the host tissue. ... | 10/26/2006 |
| 20060147492 | Medical implants and anti-scarring agents Implants are used in combination with an anti-scarring agent in order to inhibit scarring that may otherwise occur when the implant is placed within an animal. The agent may be any suitable anti-scarring agent, e.g., a cell cycle inhibitor, and may be used in conjunctio... | 07/06/2006 |
| 20060127438 | Compositions and methods for coating medical implants Medical implants are provided which release an anthracycline, fluoropyrimidine, folic acid antagonist, podophylotoxin, camptothecin, hydroxyurea, and/or platinum complex, thereby inhibiting or reducing the incidence of infection associated with the implant. ... | 06/15/2006 |
