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Inventor: Omid C. Farokhzad


Address: Chestnut Hill, MA
No. of applications: 21
Last application issue date: 12/08/2011

Application No.Application TitleIssue Date
20110300219NANOSTRUCTURES FOR DRUG DELIVERY
The present invention provides compositions, preparations, formulations, kits, and methods useful for treating subjects having cancer or at risk of developing cancer. Some embodiments of the invention may comprise a composition comprising a plurality of particles compri...
12/08/2011
20110268805ADJUVANT INCORPORATION IN IMMUNONANOTHERAPEUTICS
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that compr...
11/03/2011
20110268804TARGETING OF ANTIGEN PRESENTING CELLS WITH IMMUNONANOTHERAPEUTICS
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that compr...
11/03/2011
20110196187MAGNETICALLY SENSITIVE DRUG CARRIERS AND DELIVERY DEVICES
Apparatuses for delivering compositions of matter comprising a magnetically sensitive drug carrier and a related drug and methods for causing the drug carriers to localize within the patient using an internal or external magnetic field are described....
08/11/2011
20110143993ENDOTHELIAL BASEMENT MEMBRANE TARGETING PEPTIDE LIGANDS
Peptides that selectively bind to antigens exposed in vascular disease or dysfunction have been identified by biopanning a phage library. The ligands are useful when attached to a substrate to be in contact with endothelial surfaces, especially those where drug delivery...
06/16/2011
20110125107METHODS AND DEVICES FOR SENSING TISSUES AND TISSUE COMPARTMENTS
An apparatus provides feedback regarding the material in which tip of the apparatus is located as the tip is advance into matter of varying resistances. The apparatus responds to a change in pressure, force, or other parameter such that when the tip reaches matter of a ...
05/26/2011
20110065807PH SENSITIVE BIODEGRADABLE POLYMERIC PARTICLES FOR DRUG DELIVERY
The present invention generally relates to polymers and particles, such as nanoparticles. The particles and polymers generally include one or more buffering components. Additionally, the particles and polymers may include two or more components that impart useful proper...
03/17/2011
20110052697Aptamer-Directed Drug Delivery
The present invention provides systems, methods, and compositions for targeted delivery of a therapeutic agent organs, tissues, cells, extracellular matrix components, and intracellular compartments. The present invention provides a complex comprising a therapeutic or d...
03/03/2011
20110027172DRUG DELIVERY SYSTEM FOR PHARMACEUTICALS AND RADIATION
The present invention provides a drug delivery system for delivery of an agent and a radiopharmaceutical agent. The drug delivery system may specifically target an organ, tissue, cells, extracellular matrix, or intracellular compartment. Typically, the drug delivery sys...
02/03/2011
20100323199POLYMERS FOR FUNCTIONAL PARTICLES
The present invention generally relates to polymers and macromolecules, in particular, to block polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of emb...
12/23/2010
20100303723DRUG DELIVERY SYSTEMS USING FC FRAGMENTS
The present invention provides drug delivery systems comprising FcRn binding partners (e.g., FcRn binding partner, Fc fragment) associated with a particle or an agent to be delivered. Inventive drug delivery systems allow for binding to the FcRn receptor and transcytosi...
12/02/2010
20100233251Vaccine Nanotechnology
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at lea...
09/16/2010
20100183727Immunonanotherapeutics that Provide IgG Humoral Response Without T-Cell Antigen
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides synthetic nanocarriers capable of eliciting an immune system response in the form of antibody production, wherein the nanocarriers ...
07/22/2010
20100144845OLIGONUCLEOTIDE SYSTEMS FOR TARGETED INTRACELLULAR DELIVERY
The present invention provides methods for deriving oligonucleotides for specific internal delivery to one or more target cell types (e.g., cancer cells). The method generally includes selecting at least once with a target cell type to provide a plurality of internalizi...
06/10/2010
20100129392Targeting of Antigen Presenting Cells with Immunonanotherapeutics
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that compr...
05/27/2010
20100129439Adjuvant Incorporation in Immunonanotherapeutics
The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that compr...
05/27/2010
20100022680Microfluidic Synthesis of Organic Nanoparticles
The present invention provides microfluidic systems and methods for the production of particles (e.g., nanoparticles) for drug delivery. The present invention provides microfluidic devices useful for production of particles by nanoprecipitation. The present invention pr...
01/28/2010
20090298710System for Screening Particles
Screening of a library of particles in vivo and/or in vitro using Polyplex Iterative Combinatorial Optimization (PICO) allows for the design of particles for targeting a specific organ, tissue (e.g., cancer), or cell. Particles may, for example, include different target...
12/03/2009
20080193536Cell-Laden Hydrogels
The present invention provides cell-laden hydrogels and hydrogel assemblies thereof for use in tissue engineering. The invention provides microscale hydrogels (i.e. microgels) having greatest dimensions ranging between about 1 μm and 1000 μm. The present invention pro...
08/14/2008
20080081074Polymers for functional particles
The present invention generally relates to polymers and macromolecules, in particular, to block polymers useful in particles such as nanoparticles. One aspect of the invention is directed to a method of developing nanoparticles with desired properties. In one set of emb...
04/03/2008
20060216231Methods for diagnosing and treating tumors and suppressing cd promoters
Methods of treating tumors, reducing white blood cell numbers, and inhibiting CD promoters are provided. ...
09/28/2006
 
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