Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Application No. | Application Title | Issue Date |
| 20110294787 | SUBSTITUTED THIOMORPHOLINE DERIVATIVES The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.... | 12/01/2011 |
| 20110288120 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS Isoquinolone derivatives of the general formula (I) are NK3 antagonists. ... | 11/24/2011 |
| 20110224247 | AZAISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.... | 09/15/2011 |
| 20110144164 | Pyridone derivatives as NK3 antagonists The present invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.... | 06/16/2011 |
| 20110130420 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS Isoquinolone derivatives of the general formula Ik″ are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia. ... | 06/02/2011 |
| 20110130407 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS Isoquinolone derivatives of the general formula I are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia. ... | 06/02/2011 |
| 20110003811 | SUBSITUTED PYRIDINE DERIVATIVES The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders. ... | 01/06/2011 |
| 20100137311 | SUBSTITUTED PYRIMIDINE DERIVATIVES The present invention relates to pyrimidine derivatives of the general formula I or salts thereof and their use.... | 06/03/2010 |
| 20100076016 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS The invention relates to compounds useful in therapy, in particular in the treatment of psychosis, to compositions comprising said compounds, and to methods of treating diseases comprising the administration of said compounds.... | 03/25/2010 |
| 20100063044 | SUBSTITUTED ANILINE DERIVATIVES The present invention relates to aniline derivatives of formula I: wherein R1, R2, R3, R4, Z and q are as defined herein; or salts thereof and their use.... | 03/11/2010 |
| 20090143369 | METHODS OF USING SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES The present invention relates to morpholine and thiomorpholine derivatives of the general formula I or pharmaceutically acceptable salts thereof and their use.... | 06/04/2009 |
| 20090143402 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS Isoquinolone derivatives of the general formula are provided. The compounds are NK3 antagonists and useful for the treatment of e.g. psychosis and schizophrenia.... | 06/04/2009 |
| 20090137571 | SUBSTITUTED MORPHOLINE AND THIOMORPHOLINE DERIVATIVES The present invention relates to morpholine and thiomorpholine derivatives or the general formula I or pharmaceutically acceptable salts thereof and their use.... | 05/28/2009 |
| 20090118285 | USE OF KCNQ-OPENERS FOR TREATING OR REDUCING THE SYMPTOMS OF SCHIZOPHRENIA The invention relates to a novel method for treating or reducing the symptoms of schizophrenia, said method comprising administering to a host in need thereof an effective amount of a compound able to selectively increase the ion flow through KCNQ potassium channels. Fu... | 05/07/2009 |
| 20080318953 | Substituted Pyridine Derivatives The present invention relates to pyridine derivatives of the general formula (I) and their use as openers of the KCNQ family potassium ion channels for the treatment of CNS disorders. ... | 12/25/2008 |
| 20060155121 | Substituted aniline derivatives The present invention relates to aniline derivatives of the general formula I or salts thereof and their use. ... | 07/13/2006 |