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| Application No. | Application Title | Issue Date |
| 20110251546 | MEDICAMENT MICRODEVICE DELIVERY SYSTEM, CARTRIDGE AND METHOD OF USE A method and device for intradermal delivery of a reconstituted medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the medicament may be located within said... | 10/13/2011 |
| 20110159047 | STABLE POWDER FORMULATIONS OF ALUM-ADSORBED VACCINES The present invention is directed to methods for preparing a stable powder formulation of an alum-adsorbed vaccine. The methods comprise atomizing a liquid formulation comprising an immunogen adsorbed onto an aluminum adjuvant to produce an atomized formulation, freezin... | 06/30/2011 |
| 20090304744 | METHODS OF ENHANCING IMMUNE RESPONSE IN THE INTRADERMAL COMPARTMENT AND COMPOUNDS USEFUL THEREOF The present invention relates to immunogenic compositions for intradermal delivery of an antigenic or immunogenic agent in combination with one or more excipients. The immunogenic compositions of the invention comprise an antigenic or immunogenic agent and at least one ... | 12/10/2009 |
| 20090299274 | Method and Device for the Delivery of a Substance An abrasion device and method for delivery of substances into the skin using a microabrader for delivering a substance into the skin are disclosed. An abrasion device with a cover is also disclosed. Such devices and methods can be effectively used to deliver bioactive s... | 12/03/2009 |
| 20080226729 | STABLE POWDER FORMULATIONS OF ALUM-ADSORBED VACCINES The present invention is directed to methods for preparing a stable powder formulation of an alum-adsorbed vaccine. The methods comprise atomizing a liquid formulation comprising an immunogen adsorbed onto an aluminum adjuvant to produce an atomized formulation, freezin... | 09/18/2008 |
| 20080103434 | Microprotrusion Arrays and Methods for Using Same to Deliver Substances into Tissue Improved microprotrusion abrasion devices having fluid retaining or directing patterns, and specific design parameters and method for delivery of substances into the skin. Various configurations of such devices are disclosed, including domed, channeled, patterned and st... | 05/01/2008 |
| 20080065005 | Method and Device for the Delivery of a Substance An abrasion device and method for delivery of substances into the skin using a microabrader for delivering a substance into the skin are disclosed. An abrasion device with a cover is also disclosed. Such devices and methods can be effectively used to deliver bioactive s... | 03/13/2008 |
| 20080021439 | Intradermal cellular delivery using narrow gauge micro-cannula A method for delivering cells into a subject by administering cells into the intradermal space of the skin of the subject by a microneedle. The cells are associated with cellular based therapeutics and vaccines and delivered by perpendicular insertion of the microneedle... | 01/24/2008 |
| 20080009785 | Topical delivery of vaccines The present invention provides improved methods for delivery of substances into the skin. It has been discovered that delivery of substances such as nucleic acids, amino acids, amino acid derivatives, peptides and polypeptides simultaneously with abrasion of the skin en... | 01/10/2008 |
| 20070190158 | PHARMACEUTICAL COMPOSITIONS IN PARTICULATE FORM A method of preparing a pharmaceutical composition is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles at ... | 08/16/2007 |
| 20070154494 | Anthrax vaccines and delivery methods Immunogenic anthrax compositions, such as anthrax vaccines, and methods for delivering immunogenic anthrax compositions and/or vaccines to a mammal. Methods include delivery to mucosal membranes and to skin. ... | 07/05/2007 |
| 20060047242 | Method and device for the delivery of a substance including a covering An abrasion device and method for delivery of substances into the skin using a microabrader for delivering a substance into the skin are disclosed. An abrasion device with a cover is also disclosed. Such devices and methods can be effectively used to deliver bioactive s... | 03/02/2006 |
| 20060018877 | Intradermal delivery of vacccines and therapeutic agents The present invention relates to methods and devices for administration of vaccines and therapeutic agents into the intradermal layer of the skin. The methods of the present invention elicit increased humoral and/or cellular response as compared to conventional vaccine ... | 01/26/2006 |
| 20050281832 | Methods of enhancing immune response in the intradermal compartment and compounds useful thereof The present invention relates to immunogenic compositions for intradermal delivery of an antigenic or immunogenic agent in combination with one or more excipients. The immunogenic compositions of the invention comprise an antigenic or immunogenic agent and at least one ... | 12/22/2005 |
| 20050244385 | Intradermal cellular delivery using narrow gauge micro-cannula A method for delivering cells into a subject by administering cells into the intradermal space of the skin of the subject by a microneedle. The cells are associated with cellular based therapeutics and vaccines and delivered by perpendicular insertion of the microneedle... | 11/03/2005 |
| 20050196380 | Method for delivering therapeutic proteins to the intradermal compartment The present invention relates to methods and devices for intradermal delivery of substances, preferably therapeutic substances by targeting the substance to the intradermal compartment of a subject's skin. Substances delivered in accordance with the methods of the inven... | 09/08/2005 |
| 20050180952 | Methods for intradermal delivery of therapeutics agents The present invention relates to methods and devices for delivering one or more biologically active agents, particularly therapeutic agents, to the intradermal compartment of a subject's skin. The present invention provides an improved method of delivery of biologically... | 08/18/2005 |
| 20050181033 | Method for delivering interferons to the intradermal compartment The present invention relates to methods and devices for intradermal delivery of substances, preferably therapeutic substances by targeting the substance to the intradermal compartment of a subject's skin. Substances delivered in accordance with the methods of the inven... | 08/18/2005 |
| 20050163711 | Intra-dermal delivery of biologically active agents The present invention relates to methods and devices for delivering one or more biologically active agents, particularly a diagnostic agent to the intradermal compartment of a subject's skin. The present invention provides an improved method of delivery of biologically ... | 07/28/2005 |
| 20050152873 | Agents for enhancing the immune response The invention relates to an immunogenic composition and methods of making and using the composition. The immunogenic composition contains a directing molecule, a stimulant and an immunogen. The stimulant and directing molecule are chemically distinct. The stimulant and ... | 07/14/2005 |
| 20050008683 | Method for delivering interferons to the intradermal compartment The present invention relates to methods and devices for intradermal delivery of substances, preferably therapeutic substances by targeting the substance to the intradermal compartment of a subject's skin. Substances delivered in accordance with the methods of the inven... | 01/13/2005 |
| 20050000514 | Medicament microdevice delivery system, cartridge and method of use A method and device for intradermal delivery of a reconstituted powdered medicament. The device includes a chamber, which is in fluid communication with a microdevice, e.g. microabrader or one or more microneedles. A cartridge containing the powdered medicament may be l... | 01/06/2005 |
