William F. Semple, a dentist, was awarded the first US Patent on chewing gum in 1869. His recipe contained powdered chalk.
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| Application No. | Application Title | Issue Date |
| 20060237080 | Patterned surfaces and polymeric microstructures within robust microfluidic channels Microfluidic channel. The channel includes a microfluidic mold defining a channel and a substrate including patterned regions. The microfluidic mold is in conformal contact with the substrate to form an irreversible seal. The patterned regions are adapted to immobilize ... | 10/26/2006 |