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| Number | Title | Issue Date |
| RE39744 | Adamantane derivatives and process for producing them In the presence of an imide compound (e.g., N-hydroxyphthalimide) shown by the formula (2): wherein R1 and R2 independently represents a hydrogen atom, a halogen atom, an alkyl group... | 07/24/2007 |
| 7161027 | Process for the oxidative purification of terephthalic acid Disclosed is a process to produce a purified carboxylic acid slurry. The process comprises removing impurities from a crystallized product in a solid liquid displacement zone to form the purified carboxylic acid slurry. The purified carboxylic acid slurry is further... | 01/09/2007 |
| 7148377 | 4-Alkoxy cyclohexane-1-amino-carboxylic acid esters and method for the production thereof The invention relates to novel 4-alkoxy-cyclohexane-1-amino-carboxylic esters of the formula (IV) in which R1 represents OR3, R2 represents alkyl, and R3 represents alk... | 12/12/2006 |
| 7094919 | Preparation of substituted aromatic carboxylic acid esters Methods for preparing substituted aromatic carboxylic acid esters are described. In particular, the invention relates a method for preparing a nitro-substituted aromatic carboxylic acid ester: Additionally the inventio... | 08/22/2006 |
| 7087558 | Process for reacting large hydrophobic molecules with small hydrophilic molecules A process for reacting relatively small hydrophilic carboxylic molecules with relatively large, hydrophobic hydrocarbon based molecules, said process comprising conducting the reacting in the presence of a sulfonic acid catalyst having solubilizing properties. In a ... | 08/08/2006 |
| 7078558 | Crystals of the sodium salt of pravastatin Lovastatin, pravastatin, simvastatin, mevastatin, atorvastatin, fluvastatin and cervastatin and derivatives and analogs thereof are known as HMG-CoA reductase inhibitors and are used as antihypercholesterolemic agents. The majority of them are produced by fermentati... | 07/18/2006 |
| 7078563 | Oxidation process for the production of alkenes and carboxylic acids A process for the oxidation of a C2 to C4 alkane to produce the corresponding alkene and carboxylic acid which process comprises contacting in an oxidation reaction zone, said alkane, molecular oxygen-containing gas, and the corresponding alken... | 07/18/2006 |
| 7074954 | Process for the oxidative purification of terephthalic acid Disclosed is a process to produce a purified carboxylic acid slurry. The process comprises removing impurities from a crystallized product in a solid liquid displacement zone to form the purified carboxylic acid slurry. The process produces purified carboxylic acid ... | 07/11/2006 |
| 7071350 | Method of introducing amino group and method of synthesizing amino acid compound The present invention relates to a method for introducing an amino group into an organic acid or an organic ester by reacting an organic salt or an organic ester and ammonia under high-temperature and high-pressure water conditions, a method for synthesizing an amin... | 07/04/2006 |
| 7071349 | Purification method of N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine The present invention is to provide a purification method of obtaining N-(1(S)-ethoxycarbonyl-3-phenylpropyl)-L-alanine of high quality in good yield with high productivity, which is accordingly suited for commercial scale application. An impurity-contaminate... | 07/04/2006 |
| 7067555 | Sertraline oral concentrate The present invention provides an essentially nonaqueous, liquid pharmaceutical concentrate composition for oral administration containing sertraline or a pharmaceutically acceptable salt thereof and one or more pharmaceutically acceptable excipients. The present in... | 06/27/2006 |
| 7064146 | Pharmaceutical compositions of isolated orthorhombic crystalline 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid and methods of use A pharmaceutical composition, comprising: a compound of formula (1) in polymorphic crystalline Form A: together with a pharmaceutically acceptable carrier or excipient, wherein ... | 06/20/2006 |
| 7064147 | Amino acids with affinity for the α-2-delta-protein This invention relates to certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. ... | 06/20/2006 |
| 7060854 | Process for making polymorphic form A of 4-[6-acetyl-3-[3-(4-acetyl-3-hydroxy-2-propylphenylthio)propoxy]-2-propylphenoxy]butyric acid Process for making a pharmaceutical composition, comprising: a compound of formula (1) in crystalline form: together with a pharmaceutically acceptable carrier or excipient, wherein the compound of formul... | 06/13/2006 |
| 7060853 | Method for increasing oxidation reactor production capacity The present invention relates to a method for increasing the production capacity of a conventional oxidation reactor for catalytic liquid phase oxidation of paraxylene by staging the oxidation reaction into a first high pressure and high solvent ratio reaction zone ... | 06/13/2006 |
| 7060200 | Multireactive polymerizable mesogenic compounds The invention relates to multireactive polymerizable mesogenic compounds of formula I R1—MG—R2I wherein R1, R2 and MG have the meaning given in claim 1, to a polymerizable mesogenic compositi... | 06/13/2006 |
| 7057067 | Process for the preparation of 2-halobenzoic acids The present invention provides a process for producing 2-halobenzoic acids of the general formula (I), characterized by reacting a benzoic acid of formula (II) with a halogenating agent in the presence of Pd catalyst: ... | 06/06/2006 |
| 7049459 | 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone and a process for preparing the same This invention relates to 1-[(4-methyl thio)phenyl]-2-(phenyl acetoxy)-1-ethanone. This compound is convertible into 4-(4-methyl thio phenyl)-3-phenyl-2 (5H)-furanone by an economically viable process. This substituted furanone is an intermediate or starting compoun... | 05/23/2006 |
| 7049342 | Substituted phenylpropionic acid derivatives The invention provides novel substituted phenylpropionic acid derivatives that bind to the receptor as ligands of human peroxisome proliferator-activated receptor α (PPARα) to activate and exhibit potent lipid-decreasing action, and processes for preparing them. | 05/23/2006 |
| 7049465 | Process for energy recovery in processes for the preparation of aromatic carboxylic acids This invention relates to a process for the manufacture of aromatic carboxylic acids by exothermic liquid phase oxidation of an aromatic feedstock. More particularly, this invention relates to the efficient energy recovery of the exotherm produced by the liquid phas... | 05/23/2006 |
| 7045651 | Production process for hydroxyalkyl (meth) acrylate The present invention provides a novel production process for a hydroxyalkyl (meth)acrylate, in which it is possible that: in a batch reaction system, the amount of the hydroxyalkyl (meth)acrylate (which is the objective product) as produced is kept nearly on the sa... | 05/16/2006 |
| 7041848 | Method for oxidizing hydrocarbons into acids The present invention relates to a process for oxidizing hydrocarbons, in particular branched or unbranched saturated aliphatic hydrocarbons, cycloaliphatic or alkylaromatic hydrocarbons to acidic or polyacidic compounds. The invention relates more particular... | 05/09/2006 |
| 7041849 | Method of recovering polymerization inhibitor and method of producing acrylic acid In an acrylic acid production process which comprises the step of producing acrylic acid by catalytic vapor-phase oxidation of propane, propylene, and/or acrolein; and purifying the acrylic acid produced in the step of producing with distillation in the presence of ... | 05/09/2006 |
| 7030264 | Bis-β-hydroxyethyl terephthalate Bis-β-hydroxyethyl terephthalate having an optical density measured in a 10 wt % methanol solution at a measurement wavelength of 380 nm and a cell optical path length of 10 mm of 0.000 to 0.006. The present invention makes it clear that purified BHET having an opt... | 04/18/2006 |
| RE39074 | Process for the selective preparation of acetic acid using a molybdenum and palladium based catalytic oxide The present invention relates to a process for the selective preparation of acetic acid from a gaseous feed comprising ethane, ethylene or mixtures thereof plus oxygen at elevated temperature, which comprises bringing the gaseous feed into contact with a catalyst co... | 04/18/2006 |
| 7026360 | Pharmaceutical compositions containing compounds with activity for the enhancement of absorption of active ingredients The new pharmaceutical compositions contain, apart from one or more active ingredient(s), between 0.01 and 60% w/w of the compounds of formula I with n and m>18 and | 04/11/2006 |
| 7026501 | Inhibitors of α4 mediated cell adhesion The present invention relates to a phenylalanine derivative of Formula (I) wherein X1 is a halogen atom, X2 is a halogen atom, Q is a CH2R— is a carboxyl group which may be esterified; or a pharmaceutically acceptable salt thereof.... | 04/11/2006 |
| 7019170 | Process for the recovery of lactic acid by contacting aqueous solutions containing the same with a basic organic extractant The invention provides a process for the recovery of lactic acid and products thereof from an aqueous solution containing free lactic acid and at least one lactate salt at a total concentration of at least 5%, the process comprising the steps of: extracting at least... | 03/28/2006 |
| 7019034 | Compositions and methods for reducing serum glucose and triglyceride levels in diabetic mammals Diabetic mammals are treated with compounds that are significantly more efficacious as agonists of RXRβ retinoid receptors than as agonists of RXRα or RXRγ retinoid receptors. The treatment reduces serum glucose and triglyceride l... | 03/28/2006 |
| 7012155 | Process for the production of carboxylic acids Aliphatic carboxylic acids of formulae (Ib) R1—COOH(Ia) and R2—COOH wherein R1 is tertiary C4-20-alkyl and R2 together are —(CH2)n— with n=3 to 10, are produced by oxidizing an alip... | 03/14/2006 |
| 7012158 | Processes for the production of α-difluoromethyl ornithine (DFMO) Provided are processes and synthetic intermediates useful for the preparation of α-difluoromethylornithine (DFMO) having the formula ... | 03/14/2006 |
| 7005449 | Tolterodine salts The present invention concerns novel pharmaceutically active compounds, pharmaceutical compositions containing the same, the compounds for use as medicaments, and use of the compounds for the manufacture of specific medicaments. The present invention also concerns a... | 02/28/2006 |
| 7005540 | Method of purifying aromatic polycarboxylic acid Crude polycarboxylic acid is slurried in an aqueous medium and the slurry is brought into contact with a metal catalyst while preventing catalyst components thereof from contaminating crystals. Since hydrogenation or decarbonylation of a polymerization inhibitory su... | 02/28/2006 |
| 7005537 | Production of esters Disclosed is a process for the production of esters. In particular, the process includes contacting an olefin or an ether with carbon monoxide and an acid composition comprising BF3.2CH3OH to from a product composition, adding an alcohol to the... | 02/28/2006 |
| 7001886 | Hot melt method for preparing diphenhydramine tannate The invention pertains to a method for preparing diphenhydramine tannate by reacting diphenhydramine free base at a temperature of about 75 to about 150° C. with tannic acid neat or as an aqueous slurry containing up to about 20 wt. % water. The diphenhydramine fre... | 02/21/2006 |
| 7002035 | Color stabilization of base-stabilized ethylenically modified unsaturated monomers The invention relates to the use of at least one compound from the tocopherol group for the color stabilization of ethylenically unsaturated monomers, particularly hydroxyalkyl(meth)acrylates, which already comprise at least one polymerization inhibitor for base sta... | 02/21/2006 |
| 7001625 | Solid phase synthesis of salts of organic acids including butyric acid A process for the solid-phase synthesis of salts of organic acids in a granular, free-flowing, and dust-free form particularly suited for use as animal feed additives. A mixture of liquid organic acids, including butyric acid, is applied to an inert, absorbent carri... | 02/21/2006 |
| 7002037 | Process for the preparation on enantiomerically enriched compounds The present invention relates to novel resolution methods, which are useful in the preparation of enantiomerically enriched intermediates which in their turn are useful in the prepartion of compounds with a pharmacological effect on the insulin resistance syndrome (... | 02/21/2006 |
| 6998504 | Method for the catalytic gas phase oxidation of propene into acrylic acid A process for the catalytic gas-phase oxidation of propene to acrylic acid, in which the reaction gas starting mixture is oxidized, with a high propene loading, in a first reaction stage, over a first fixed-bed catalyst which is housed in two successive reaction zon... | 02/14/2006 |
| 6995151 | Isophthalic acid derivatives as matrix metalloproteinase inhibitors Selective MMP-13 inhibitors are isophthalic acid derivatives of the formula wherein: R1, R2, and R3 independently are hydrogen, halo, hydroxy, C1 | 02/07/2006 |
