Did You Know...
...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!
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| Number | Title | Issue Date |
| 5576351 | Use of arginine as an immunostimulator The present invention relates to the treatment of an impaired human immune response or to reduction of the severity of degradation of the human immune response by the administration of arginine or ornithine, or a functional analog of arginine or ornithine... | 11/19/1996 |
| 5464862 | Method for inhibiting bone loss using centchroman derivatives Methods and pharmaceutical compositions for reducing bone loss are disclosed. 3,4-diarylchromans and their pharmaceutically acceptable salts are formulated into medicaments for the treatment of bone loss due to osteoporosis or other conditions. An exempla... | 11/07/1995 |
| 5459135 | Composition comprising indomethacin [non-steroidal anti-inflammatory agent] and effectively non-antibacterial tetracycline to reduce bone loss A method for treating mammals suffering from rheumatoid arthritis and other tissue-destructive (chronic inflammatory or other) conditions associated with excess metalloproteinase activity comprising administering to the mammal an amount of a tetracycline ... | 10/17/1995 |
| 5459136 | Methods using vitamin D compounds for improvement of skin conditions Compositions containing vitamin D compounds in a suitable carrier and methods employing such compositions are disclosed for cosmetic uses in the treatment of various skin conditions such as lack of adequate skin firmness, wrinkles, lack of dermal hydratio... | 10/17/1995 |
| 5457132 | Kit used in the treatment for hypertension using combination therapy involving exogenous calcium and calcium channel blockers A kit containing benzeneacetonitrile and calcium or dihydropyridine and calcium hypertensive mammals may be treated to lower mean blood pressure by administering a calcium channel blocking agent together with one or both of a calcium supplement and Vitami... | 10/10/1995 |
| 5453436 | Treatment of athereosclerosis using, carbazolyl-(4)-oxypropanolamine compounds A new use of, and method of treatment of atherosclerosis using, a compound selected from the group consisting essentially of compounds of Formula I: ##STR1## wherein: R1 is hydrogen, lower alkanoyl of up to 6 carbon atoms or aroyl selected... | 09/26/1995 |
| 5447953 | Biomasses to treat non-human animals The use of biomasses obtained in the fermentative production of lipase inhibitors, especially lipstatin, for the preparation of foodstuffs, feedstuffs, food additives, feed additives, feed supplements, medicinal feed premixes or medicaments for oral admin... | 09/05/1995 |
| 5447956 | Treatment of leukemia with a imidazo carbamate Use of Methyl N-[6-(3,4,5-trimethoxybenzyloxy)imidazo [1,2-6]pyridazin-2-yl]carbamate or pharmaceutically acceptable salt to treat lymphocytic leukemia is disclosed.... | 09/05/1995 |
| 5447923 | Methods and compositions of diphenyl ether phosphate esters for the treatment of gastrointestinal disorders Methods for the treatment of a human or lower animal subject having an H. pylori-mediated upper gastrointestinal disorder comprising administering to said subject a safe and effective amount of a diphenyl ether phosphate ester of the following formula: ... | 09/05/1995 |
| 5444069 | Imidazo-pyridine angiotensin II antagonists used to treat memory loss The present invention relates to the use of 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-6-carboxylic acids and analogs thereof in antagonizing the binding of angiotensin II to AT2 receptors to treat memory loss.... | 08/22/1995 |
| 5443850 | Method for treating symptoms associated with vascular headaches by administering a combination of calcium and vitamin D The present invention is directed to a method for treating symptoms associated with vascular headaches. The method comprises administering to an individual exhibiting symptoms associated with vascular headache symptomatology a therapeutically effective am... | 08/22/1995 |
| 5436273 | Psychoactive propargylamine derivatives used in the treatment of anxiety, psychotic states or aggression Propargylamine derivatives having the general formula: ##STR1## wherein R is a hydrogen atom, an unsubstituted phenyl group or a phenyl group substituted with halogen, trifluoromethyl, loweralkoxy, nitro, cyano, amido or N,N-diloweralkylamido, R... | 07/25/1995 |
| 5436251 | Treatment of anxiety and gastrointestinal disorders with azabicyclo carbonyl-2-(cyclopropylmethyloxy)benzamide (Endo)-N-[[[8-azabicyclo[3.2.1]octan-3-yl]amino]carbonyl]-2-(cyclopropylmet hyloxy)benzamide and pharmaceutically acceptable salts thereof possess 5-HT3 antagonistic activity and are useful in the treatment of neuro-psychiatric disorders (e.g. a... | 07/25/1995 |
| 5434177 | Imidazoles for the treatment of age-related cognitive disorders and alzheimer This invention relates to the use of a compound of formula ##STR1## wherein X is --CH2 -- or ##STR2## R1 is H, C1-5 -alkyl or benzyl, which can be substituted of unsubstituted; R2 is H, C1-4... | 07/18/1995 |
| 5434166 | Methods of inhibiting demyelinating and desmyelinating diseases A method of inhibiting demyelinating or dysmyelinating diseases or their symptoms comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R1 and R3 are independen... | 07/18/1995 |
| 5430051 | Treatment of arthritis using derivatives of porphorins A method for the photodynamic therapy of rheumatoid arthritis of mammals, which agent comprises at least one member of fluorescent compounds selected from the group consisting of tetrapyrrole carboxylic acids having at least one carboxyl group, correspond... | 07/04/1995 |
| 5430030 | Nerve gas antidote A prophylactic pretreatment for nerve gas and pesticide poisons which can be administered orally and which comprises the following agents, in combination: a. Pyridostigmine (pyridostigmine bromide) b. Diazepam c. N-methyl-4-pipyridinyl phenylcyclopentanec... | 07/04/1995 |
| 5430058 | Pharmaceutical compositions comprising hydroxamate derivatives for iron removal Pharmaceutical compositions comprising compounds of the formula: R2 C{CH2 O(CH2)n CO[NR3 CHR(CH2)m CO]q NOHR1 }3, wherein R is hydrogen, alkyl optiona... | 07/04/1995 |
| 5428063 | Use of betaine as a hepatic generator of S-adenosylmethionine and as a protective agent against hepatotoxicity This invention encompasses pharmaceutical compositions in the dietary supplement for treating or preventing fatty infiltration, the first stage of cirrhosis of the liver comprising and administering of not less than 1500 mg of betaine per kg of body weigh... | 06/27/1995 |
| 5428069 | Treating cognition with, aminocyclopropanecarboxylic derivatives The use of a compound possessing functional antagonist properties at the NMDA receptor complex through a specific action at the associated strychnine-insensitive glycine site to improve cognition in normal humans and to treat cognitive deficits resulting ... | 06/27/1995 |
| 5426122 | Methods for reducing blood pressure with dimercaptosuccinic acid (DMSA) Methods for treatment of humans and other animals with dimercaptosuccinic acid (DMSA). DMSA is administered to reduce levels of silicon in blood and tissue, reduce blood pressure, improve kidney function, prevent or retard the progression of chronic renal... | 06/20/1995 |
| 5424463 | Ɗ5-androstenes useful for promoting weight maintenance or weight loss and treatment process A method for promoting weight control by treating a subject with a therapeutic amount of one of the Ɗ5-androstenes listed below to stimulate weight control without affecting appetite or inducing the synthesis of sex hormones. Ɗ5-Androstenes providing th... | 06/13/1995 |
| 5422393 | Natriuretic hormone A purified naturally occurring natriuretic compound, identified as Natriuretic Hormone, and a method for isolation of the compound. The natriuretic compound has a molecular weight of about 360, a molecular formula of C21 H28 O5 | 06/06/1995 |
| 5422096 | Hydroxy-aryl metal chelates for diagnostic NMR imaging An NMR contrast agent composition contains a complex of a selected metal ion and a selected ligand. The ion is selected from the group consisting of gadolinium (III), iron (III), manganese (II), manganese (III), chromium (III), copper (II), dysprosium (II... | 06/06/1995 |
| 5422361 | Stable cream and lotion bases for lipophilic drug compositions A cosmetically elegant, physically and chemically stable base in the form of an oil-in-water emulsion for use in cream and lotion lipophilic drug containing- pharmaceutical compositions containing at least one lipophilic drug and an effective amount of N-... | 06/06/1995 |
| 5420121 | Use of 4-cholesten-3-one as an anti-obesity agent The present invention provides a method for using the anti-obesity agent comprising 4-cholesten-3-one represented by the following formula: ##STR1## as an effective component. The anti-obesity agent of the present invention is useful because of inhib... | 05/30/1995 |
| 5417986 | Vaccines against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres This invention is directed to oral parenteral and intestinal vaccines and eir use against diseases caused by enteropathogenic organisms using antigens encapsulated within biodegradable-biocompatible microspheres.... | 05/23/1995 |
| 5416105 | Treating an arteriosclerosis with glimepiride A pharmaceutical composition containing as an active ingredient glimepiride. The composition is used for preventing or treating arteriosclerosis with no influence on lipid metabolism and no increase in plasma insulin level.... | 05/16/1995 |
| 5409690 | Treatment of multidrug resistant diseases in cancer cell by potentiating with masoprocol Disclosed are: a method for reversing multidrug resistance in a mammal; and a composition to reverse multidrug resistance comprising: ##STR1## wherein R1 and R2 are independently H, lower alkyl or lower acyl; R3, R | 04/25/1995 |
| 5407924 | Method of treating pain using inositol triphosphate A method of preventing or alleviating pain by administering to a human or other mammal in need thereof of a pain preventing or alleviating effective amount of a pharmaceutical composition comprising at least one specific isomer of inositol triphosphate.... | 04/18/1995 |
| 5407927 | Treatment of mild depression and restoration of IGF-I levels in aging by dehydroepiandrosterone This invention relates to the treatment of mild depression in an aging patient population. The invention specifically relates to daily treatment with dehydroepiandrosterone to increase insulin-like growth factor-I serum levels and increase psychological w... | 04/18/1995 |
| 5405855 | Treatment of insulin resistant diabetes with thalidomine A method for treating insulin-resistant diabetes in mammals which comprises administering to said afflicted animals a prophylactically or therapeutically effective amount of thalidomide.... | 04/11/1995 |
| 5403834 | Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease The invention provides antioxidant salen-metal complexes in a form suitable for pharmaceutical administration to treat or prevent a disease associated with cell or tissue damage produced by free radicals such as superoxide.... | 04/04/1995 |
| 5403858 | New compositions containing taxane derivatives Compositions containing taxane derivatives, consist of a solution of such derivative in a surfactant consisting of polysorbate, polyethelene glycol or hydrogenated castor oil. These compositions can be used to prepare perfusion solutions essentially free ... | 04/04/1995 |
| 5403831 | Method of treating and preventing loss of bone mass using 1-hydroxy-vitamin D2 A method for reversing loss of bone mass or bone mineral content in a human being suffering from osteoporosis is disclosed which comprises administering to the human being a daily dosage of at least 2.0 micrograms/day of 1-alpha-hydroxy-Vitamin D2. | 04/04/1995 |
| 5403829 | Use of bisphosphonates in endo-osteal bone surgery A method of enhancing the formation of bone tissue and/or eliminating late complications subsequent to bone surgery comprising administering an amount, which is safe and sufficient to promote the formation of bone tissue and/or eliminate late complication... | 04/04/1995 |
| 5401767 | Compounds which inhibit complement and/or suppress immune activity The present invention is directed to compounds which suppress immune responses and/or selectively inhibit complement. These compounds contain an aromatic ring and are substituted dihydrobenzofurans, spirobenzofuran-2(3H)-cycloalkanes, and their open chain... | 03/28/1995 |
| 5397784 | Stable parenteral compositions of vinblastine or vincristine The invention relates to novel, parenterally useful, stable aqueous pharmaceutical compositions, mainly injectable solutions containing a bis-indole alkaloid. The compositions contain the zinc complex of a bis-indole alkaloid, preferably vincristine, vinb... | 03/14/1995 |
| 5395610 | Agents for potentiating the effects of antitumor agents and combating multiple drug resistance Potentiating agents which enhance the efficacy of antineoplastic agents are disclosed. The potentiating agents disclosed are dibenz[b,e]oxepins such as doxepin.... | 03/07/1995 |
| 5395830 | Method of treating osteoporosis with 1,24(R)-dihydroxy-22(E)-dehydro-vitamin D3 A method of treating osteoporosis comprising the administration of an effective amount of 1,24(R)-dihydroxy-22(E)-dehydro-vitamin D3.... | 03/07/1995 |
