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| Number | Title | Issue Date |
| 7538133 | Benzimidazole derivatives, their production and use Benzimidazole derivatives of the formula (I): wherein the ring A is a benzene ring which may optionally contain substitution in addition to the R′ group; R1 is hydrogen or an optionally substituted hydrocarbon ... | 05/26/2009 |
| 7538132 | Isoxazolo derivatives The present invention is concerned with aryl-isoxazole-4-carbonyl-pyrrole-2-carboxylic acid amide derivatives of formula wherein R1, R2, R3, R4, and R5, an... | 05/26/2009 |
| 7538072 | Stem/leaf desiccant A stem/leaf desiccant for crop plants which comprises as an active ingredient, a compound of formula (I): wherein X represent CH or nitrogen; Z represents halogen; A represents oxygen, sulfur, or NH; R1 represent... | 05/26/2009 |
| 7534795 | Compounds and their use related to compositions for treating disease Novel compounds and their uses are disclosed herein. ... | 05/19/2009 |
| 7534896 | Process for the synthesis of perindopril and its pharmaceutically acceptable salts Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ... | 05/19/2009 |
| 7534880 | Clear photopolymerizable systems for the preparation of high thickness coatings The present invention relates to clear photopolymerisable systems for the preparation of high thickness coatings, to a procedure for their application and to the solid surfaces coated with them. ... | 05/19/2009 |
| 7534804 | Benzoxazole inhibitors of 15-lipoxygenase The present application provides benzoxazole inhibitors of 15-LO, pharmaceutical compositions containing such inhibitors and methods for treating diseases related to the 15-LO cascade using such compounds and compositions. ... | 05/19/2009 |
| 7531563 | Thiazoline acid derivatives The present invention relates to novel thiazoline acids and derivatives thereof useful as chelators of trivalent metals in therapeutic applications. For example, the thiazoline acid derivatives are useful in diagnosing and treating pathological conditions associated... | 05/12/2009 |
| 7528263 | Oxidation process for the preparation of N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3-{N-[(tert-butylamino)carbonyl]-3-methyl-L-valyl}-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide and related compounds The present application relates to a process for preparing a compound of formula I: wherein R1 is alkyl; R2 is alkyl; and... | 05/05/2009 |
| 7528131 | Substituted morpholinyl compounds This disclosure relates to novel substituted morpholinyl compounds and their derivatives, pharmaceutically acceptable salts, solvates, and hydrates thereof. This disclosure also provides compositions comprising a compound of this disclosure and the use of such compo... | 05/05/2009 |
| 7524867 | Tetrasubstituted imidazole derivatives as cannabinoid CB receptor modulators with a high CB/CBreceptor subtype selectivity The present invention relates to 1,2,4,5-tetrasubstituted imidazole derivatives as selective cannabinoid CB1 receptor modulators, in particular CB1 receptor antagonists or inverse agonists having a high CB1/CB2 receptor su... | 04/28/2009 |
| 7524970 | Compounds A compound of formula (I): wherein X represents O or S; R1 represents C1-6 alkyl, C3-8 cycloalkyl, C3-8 cycloalkylmethyl or C | 04/28/2009 |
| 7524876 | Luciferin derivatives A compound represented by the following general formula (I) or a salt thereof: [wherein R1 and R2 represent hydrogen atom, a C1-6 alkyl group, or a group represented... | 04/28/2009 |
| 7524858 | Substituted pyrroline kinase inhibitors The present invention is directed to novel substituted pyrroline compounds useful as kinase inhibitors and methods for treating or ameliorating a kinase mediated disorder. ... | 04/28/2009 |
| 7521449 | 4-arylmorpholin-3-one derivatives, their preparation and therapeutic use thereof The invention relates to compounds corresponding to formula (I): in which: Ar represents a mono- or disubstituted phenyl; R1 represents an unsubstituted or subs... | 04/21/2009 |
| 7521471 | 4-cyanopyrazole-3-carboxamide derivatives, preparation and application thereof The invention relates to 4-cyanopyrazole-3-carboxamide derivatives of formula (I): in which R1, R2, R3, R4, R5, R6, R7, R8 are as descr... | 04/21/2009 |
| 7521469 | Phosphinic amino acid compounds Compounds of formula (I): wherein: R1 represents hydrogen, alkylcarbonyloxyalkyl or alkylcarbonylthioalkyl, R2 represents hydrogen, alkylcarbonyloxyalkyl, arylcarbonylthioalky... | 04/21/2009 |
| 7521397 | Disubstituted pyrazolyl carboxanilides This invention relates to novel pyrazolylcarboxanilides of formula (I) in which R, R1, R2 and R3 are as defined in the disclosure, to a plurality of processes for pr... | 04/21/2009 |
| 7517868 | Phytic citrate compounds and process for preparing the same The present invention provides a chemical compound or a salt thereof having the chemical formula of: wherein said R is H or citrate and wherein at least one R is citrate. The salt of the chemical compound is the Na+ | 04/14/2009 |
| 7518012 | Process for the preparation of dialkyl carbonate The present invention provides a process for the preparation of dialkyl carbonates of general formula (1) wherein R=alkyl (C1-C8) or C6H5CH2 | 04/14/2009 |
| 7518011 | Method of preparing ester-substituted diaryl carbonates The present invention relates to an interfacial method of preparing ester-substituted diaryl carbonates. The method includes the steps of: forming a reaction mixture comprising phosgene, an ester-substituted phenol, an organic solvent, and a catalyst selected from t... | 04/14/2009 |
| 7517898 | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof Compounds of formula (I) or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4 and Z are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared.... | 04/14/2009 |
| 7514459 | Gamma-secretase inhibitors Compounds of formula I: are potent inhibitors of gamma-secretase and hence find use in treatment or prevention of diseases associated with deposition of β-amyloid. ... | 04/07/2009 |
| 7514569 | Benzimidazolone compound A benzimidazolone compound represented by a general formula (1), (in the formula, each of R1, R2, R3 and R4 represents independently a hydrogen atom, an alkyl group having 1 to 5 ... | 04/07/2009 |
| 7514432 | Compounds and methods of treating cell proliferative diseases, retinopathies and arthritis The present invention relates to compounds and their uses, particularly in the pharmaceutical industry. The invention discloses compounds having anti-proliferative and antiangiogenic activities, as well as methods for treating various diseases associated with abnorm... | 04/07/2009 |
| 7514446 | Pyrimidine compounds The present invention provides compounds of formula (I): wherein all variables are as defined herein, pharmaceutical compositions containing the same, processes for preparing the same and their use as pharmaceutical agents.... | 04/07/2009 |
| 7511073 | Amines that inhibit a mammalian anandamide transporter, and methods of use thereof One aspect of the present invention relates to amines. A second aspect of the present invention relates to the use of the amines as inhibitors of a mammalian anandamide transporter. The compounds of the present invention will also find use in the treatment of numero... | 03/31/2009 |
| 7511068 | Mercaptoimidazoles as CCR2 receptor antagonists The present invention relates to a compound of formula (I) having CCR2 receptor antagonistic properties, particularly anti-inflammatory properties. ... | 03/31/2009 |
| 7511061 | Triazoles as farnesyl transferase inhibitors A prodrug, N-oxide, addition salt, quaternary amine or stereochemically isomeric form thereof, wherein L1 and L2 are R1—Y— wherein each (R1—Y)— substituent is defined independently of the other; Y is C1-4 | 03/31/2009 |
| 7511058 | Heterocyclic inhibitors of MEK and methods of use thereof Disclosed are compounds of the Formula III and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, R7, R8, R9 R10, and W are as defined i... | 03/31/2009 |
| 7511046 | Thienoisoxazolyl- and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as Dantagonists The compounds are of the class thienoisoxazolyl- and thienylpyrrazolyl-phenoxy substituted propyl derivatives, useful as D4 antagonists. Said compounds are useful for the treatment of medical conditions mediated by inhibition of D4 receptor. Th... | 03/31/2009 |
| 7511154 | Preparation of N-protected-3-pyrrolidine-lactam substituted phosphonium salts A process for producing the compound (1′benzyl-2-oxo-[1,3′]-(R)-bipyrrolidinyl-3-(R,S)-yl)-triphenyl-phosphonium bromide which is an intermediate for antibacterial vinylpyrrolidinone-cephalosporin derivatives. ... | 03/31/2009 |
| 7507759 | Methods of using(+)-2-[1-(3-ethoxy-4methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3,-dione Stereomerically pure (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, substantially free of its (−) isomer, and prodrugs, metabolites, polymorphs, salts, solvates, hydrates, and clathrates thereof are discussed. Also d... | 03/24/2009 |
| 7504427 | Fluoroalkoxy-substituted 1,3-dihydro-isoindolyl compounds and their pharmaceutical uses The invention encompasses novel compounds, pharmaceutically acceptable salts, hydrates, solvates, clathrates, enantiomers, diastereomers, racemates, or mixtures of stereoisomers thereof, pharmaceutical compositions of these compounds, and methods of using these comp... | 03/17/2009 |
| 7501449 | 2-or 3-benzo[e]indazol-1-yl carbamate derivatives, the preparation and therapeutic use thereof Compounds corresponding to the formula (I) as defined in the disclosure as well as methods for making such compounds, intermediates employed in such methods, pharmaceutical compositions containing the compounds of the inven... | 03/10/2009 |
| 7501448 | Process for preparing telmisartan Provided are processes for preparing telmisartan alkyl ester and telmisartan using environmentally friendly organic solvents that are easily removed from the reaction mixture, wherein a telmisartan alkyl ester is isolated and hydrolyzed to form telmisartan or the te... | 03/10/2009 |
| 7501445 | Imidazolidinone compounds This invention relates to compounds of the following formula: in which R1, R2, A1, A2, X, Y, m, n, p, x and y are as defined herein, pharmaceutical compositions comprising the com... | 03/10/2009 |
| 7501447 | Benzimidazole derivatives, compositions containing them, preparation thereof and uses thereof Compounds of formula (I) or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4 and Z are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular i... | 03/10/2009 |
| 7501528 | Method for preparing enantiomerically pure 4-pyrrolidino phenylbenzyl ether derivatives The invention relates to a method for preparing enantiomerically pure 4-pyrrolidinophenylbenzyl ether derivatives of formula I: wherein R1, R21, R22, R23, R24 and n are... | 03/10/2009 |
| 7498354 | Pyrrolo[2,3-D]imidazoles for the treatment of hyperproliferative disorders or a pharmaceutically acceptable salt or N-oxide thereof, are useful in the treatment of tumors and cancers. ... | 03/03/2009 |
