Quotables
"For a list of all the ways technology has failed to improve the quality of life, please press three."
Alice Kahn
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8183060 | Luminescent polymer and use thereof in bioassay It is an object of the present invention to provide a luminescent polymer that is useful as a luminescent signal probe for labeling and detecting a target substance at high sensitivity in bioassay, and to provide the application of said luminescent polymer to bioass... | 05/22/2012 |
| 8168756 | Levetiracetam immunoassays Methods, compositions and kits are disclosed directed at levetiracetam derivatives, immunogens, signal generating moieties, antibodies that bind levetiracetam and immunoassays for detection of levetiracetam. ... | 05/01/2012 |
| 8168399 | Supports for assaying analytes and methods of making and using thereof Described herein are supports for assaying an analyte and methods of making and using thereof. ... | 05/01/2012 |
| 8158259 | Spreading layer and humidity control layer for enhancing sensor performance The invention is directed to optical sensors for measuring clinically relevant analytes, their methods of manufacture, and their various uses. In an effort to develop a dry calibration method for the optical sensors of the invention it is discovered that water conte... | 04/17/2012 |
| 8158441 | Method for detecting aggregate-forming circulating protein forms using an agent for aggregating said forms and an agent for capturing formed aggregates The present invention concerns a method for detecting aggregate-forming circulating protein forms in a biological sample of human origin that may contain said aggregate-forming circulating protein forms, characterized in that it uses a non-protein agent I producing ... | 04/17/2012 |
| 8157733 | Blood pressure measurement apparatus The present invention relates to a blood pressure measurement apparatus comprising: an input unit where at least one value selected from the maximum applied pressure, which is the applied pressure at which the maximum pulse pressure is attained during the pulse pres... | 04/17/2012 |
| 8158444 | Fluorescent methods and materials for directed biomarker signal amplification Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chr... | 04/17/2012 |
| 8153767 | Antibody against aflatoxins, support using the antibody, method of immunologically detecting aflatoxins and method of concentrating and purifying aflatoxins It is intended to detect, concentrate and purify aflatoxins of all types which are possibly contained in a sample such as a food. It is also intended to detect the total amount or the individual amounts thereof at a high sensitivity. By using aflatoxin B2 or its der... | 04/10/2012 |
| 8148173 | Polymerizable chemiluminescent compounds Disclosed are compounds having the formula: wherein R1 is selected from the group consisting of hydrogen, C1-C6 alkyl, amino, N—C1-C6-alkylam... | 04/03/2012 |
| 8137990 | Compositions for chemiluminescent detection of hydrogen peroxide Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of the formula: is reacted with peroxide. Sig is a non-polymeric organic group, B is a boron atom, and each... | 03/20/2012 |
| 8133695 | Fluorescence polarization hERG assay Disclosed are assays, methods, and kits for the screening of test compounds for their capability to induce cardiotoxicity in a subject. In particular, whether a test compound has the effect to prolong the Q-T interval as measured by an electrocardiogram in a human. ... | 03/13/2012 |
| 8133743 | Phenobarbital derivatives useful in immunoassay Phenobarbital derivatives synthesized out of the alkyl chain at the 5-position, particularly with hydrophilic properties, and carrying an active ester at the end, allow formation of aminodextran conjugates that give curves in the desired range of the assay in the ON... | 03/13/2012 |
| 8133694 | Functional vitamin D derivatives and method of determining 25-hydroxy- and 1α, 25-dihydroxy vitamin D The preparation of vitamin D compounds of formula (I) with a label attached to a spacer group in the 3 position is disclosed. In the above formula (I), O represents the oxygen atom of an ether group; Y represents hydrogen o... | 03/13/2012 |
| 8129505 | Comb polymers The present invention provides a process for producing a comb polymer comprising the steps of: a) providing: (i) (w+z) molar equivalents of a monomer; (ii) one molar equivalent of an initiator compound of formula (IX), wherein B3 represents a halogen, B | 03/06/2012 |
| 8124789 | Method for producing glycosylated indole compound and antibody against the compound This invention provides a method of producing a large amount of an α-form or β-form of N-pyranosyl-tryptophan having a specified structure and preparing an antibody therefrom. The method comprises a step of allowing a pyranose compound to react with a 3-pyrazyl-in... | 02/28/2012 |
| 8124364 | Biotin derivatives A method for the conditioning of an extracorporeal device is described, as well as method for extracorporeal extraction of toxic material from mammalian body fluids in connection with diagnosis or treatment of a mammalian condition or disease, in which methods reage... | 02/28/2012 |
| 8119422 | Stable acridinium esters with fast light emission Chemiluminescent acridinium esters are provided which are fast light emitting and hydrolytically stable. The chemiluminescent acridinium esters are useful labels in assays for detecting or quantifying analytes. ... | 02/21/2012 |
| 8114621 | Lenalidomide and thalidomide immunoassays Novel conjugates and immunogens derived from lenalidomide and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of thalidomide and lenalidomide in biological fluids. ... | 02/14/2012 |
| 8110656 | Compositions and methods of a phosphatidic acid binding protein TGD2 proteins of Arabidopsis are proposed to be a substrate binding component of a lipid transfer complex in the inner chloroplast envelope membrane. Loss of function of this protein or other components of this complex may disrupt the endoplasmic reticulum (E... | 02/07/2012 |
| 8105821 | Silane mixtures Silanation compositions containing a mixture of two or more silanation reagents, where at least one silanation reagent includes a functional group capable of supporting polymer synthesis and at least one silanation reagent includes no functional group capable of sup... | 01/31/2012 |
| 8088594 | Risperidone immunoassay Novel conjugates and immunogens derived from risperidone and antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of risperidone and paliperidone in biological fluids. ... | 01/03/2012 |
| 8084586 | Doxorubicin immunoassay Novel conjugates of doxorubicin and novel doxorubicin immunogens derived from the 13 and 14 positions of doxorubicin and antibodies generated by these doxorubicin linked immunogens all of which are useful in immunoassays for the quantification and monitoring of doxo... | 12/27/2011 |
| 8076160 | Drug monitoring assay A method for obtaining at least one binding agent which binds a pharmaceutically active form of the compound with a higher specificity than a pharmaceutically inactive form of the compound is described by using special derivatives of said parent compound. The invent... | 12/13/2011 |
| 8076097 | Imatinib immunoassay Novel conjugates and immunogens derived from imatinib and monoclonal antibodies generated by these immunogens are useful in immunoassays for the quantification and monitoring of imatinib or its pharmacologically active salts in biological fluids. ... | 12/13/2011 |
| 8071177 | Substrate and method for producing the substrate A self assembling monolayer formed by the self assembling molecules is caused to bond onto the surface of a base material, and chelators are caused to bond onto the self assembling monolayer, to produce a substrate, in which the chelators are bound to the self assem... | 12/06/2011 |
| 8053205 | Doxorubicin immunoassay Novel conjugates of doxorubicin and novel doxorubicin immunogens derived from the 13 and 14 positions of doxorubicin and antibodies generated by these doxorubicin linked immunogens all of which are useful in immunoassays for the quantification and monitoring of doxo... | 11/08/2011 |
| 8053194 | Labeling substance and chimeric substance and method for preparing the same and method for capturing, structurally analyzing and/or identifying biological substance by means of the labeling substance Disclosed is a labeling substance capable of reversibly immobilizing (reversible detachment) to a solid surface and to reliably and accurately identify a target biological substance interacting with a probe substance bound to the labeling substance. A chimeric compo... | 11/08/2011 |
| 8053564 | Cross-linked antibodies The present invention provides a compound consisting essentially of the following elements: one or more reactive groups; and two or more cross-linked antibodies or fragments thereof; characterised in that the or each reactive group is suitable for attaching an effec... | 11/08/2011 |
| 8053565 | Multi-media affinity column to prevent leaching of ligands In an affinity-type purification, ligands dissociated from a packed bed that would otherwise leach into the solution containing the species being purified are captured by a second ligand that resides in a porous barrier downstream from the packed bed, the second lig... | 11/08/2011 |
| 8039599 | Rapamycin assay Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them. ... | 10/18/2011 |
| 8039220 | Stabilized standards for busulfan immunoassay Use of busulfan amide as stabilized standards in immunoassays for quantifying the amount of busulfan in samples of human biological fluids, methods for carrying out said immunoassay and kits for use in said immunoassay. ... | 10/18/2011 |
| 8039273 | β-glucuronide-linker drug conjugates Ligand Drug conjugate compounds comprising a β-glucuronide-based linker and methods of using such compounds are provided. ... | 10/18/2011 |
| 8039600 | Rapamycin assay Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them. ... | 10/18/2011 |
| 8034636 | Hydrophilic chemiluminescent acridinium labeling reagents In accordance with the present invention, it has been discovered that introduction of hydrophilic sulfoalkyl substituents and/or hydrophilic linkers derived from homocysteic acid, cysteic acid, glycine peptides, tetraethylene oxide, and the like, offset the hydropho... | 10/11/2011 |
| 8030458 | Monoclonal antibodies to tacrolimus and immunoassays methods for tacrolimus An IgG1λ monoclonal antibody to the immunosuppressive drug tacrolimus has improved properties. In particular, this monoclonal antibody, designated 1H6, has reduced cross-reactivity to several tacrolimus metabolites. This antibody is suitable for performa... | 10/04/2011 |
| 8026109 | Hapten-carrier conjugates for treating and preventing nicotine addiction Novel hapten-carrier conjugates are capable of inducing the production of antibodies, in vivo, that specifically bind to nicotine. These conjugates comprise a nicotine hapten conjugated to an immunogenic carrier protein. The novel conjugates preserve the chirality o... | 09/27/2011 |
| 8026107 | Agglutination inhibition assay method and reagent Provided are an agglutination-inhibition assay and a reagent for agglutination-inhibition assay, which can be used for measuring a ligand in a sample at high sensitivity in a wide range from the low-concentration range to the high-concentration range and have good r... | 09/27/2011 |
| 8021889 | Chromatographic material for the absorption of proteins at physiological ionic strength Ion exchange and hydrophobic interaction chromatographic materials are constructed by tethering a terminal binding functionality to a solid support via a hydrophobic linker. The backbone of the linker typically comprises sulfur-containing moieties. Suitable terminal... | 09/20/2011 |
| 8021891 | Methods and compositions for protein detection using nanoparticle-fluorescent polymer complexes Compositions, methods and related apparatus, as can be used for selective protein detection and identification. ... | 09/20/2011 |
| 8007998 | Polymerized conjugates for biological applications Polymerized conjugates of at least two proteins that have increased sensitivity for detecting proteins in biological assays such as gels and blots, and methods of preparing the conjugates, and a protein assay detection kit using the conjugates. In one embodiment, pr... | 08/30/2011 |
