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| Number | Title | Issue Date |
| 8163299 | Stabilized pharmaceutical product Use of an adsorbent and a sealed package (e.g. an overwrap) to protect a pharmaceutical product in a solid state in the presence of a reducing sugar. ... | 04/24/2012 |
| 8128955 | Food compositions containing creatine Disclosed is a solid or semi-solid foodstuff for human consumption, the foodstuff comprising creatine suspended in solid form in an edible supporting matrix; the foodstuff being in the form of a bar. ... | 03/06/2012 |
| 8075919 | Methods for fabrication, uses and compositions of small spherical particles prepared by controlled phase separation The present invention is related to a method for preparing small spherical particles of an active agent by providing a solution in a single liquid phase. The single liquid phase comprises an active agent, a phase separation enhancing agent, and a first solvent. A ph... | 12/13/2011 |
| 8043632 | Process for making antimicrobial articles by reacting chitosan with amino-reactive polymer surfaces Polymer articles are rendered antimicrobial by a process that includes contacting a chitosan solution with a polymer surface that inherently contains amino-reactive functional groups as polymerized. The process requires no pretreatment with agents such as oxidizing ... | 10/25/2011 |
| 7988998 | Sustained-release tramadol formulations with 24-hour efficacy A sustained-release tramadol formulation oral administration is provided which, upon initial administration of one dose, provides an analgesic effect within 2 hours, which analgesic effect continues for at least 24 hours after administration. ... | 08/02/2011 |
| 7964216 | Spaced drug delivery system The present invention provides to a method of administration of two or more therapeutically active agents comprising orally administering to a patient a spaced drug delivery system, wherein the time of release of the two or more therapeutically active agents is desi... | 06/21/2011 |
| 7943175 | Calixarene based dispersible colloidal systems in the form of nanoparticles A water dispersible colloidal system in the form of generally spherical matrix type particles and of sizes typically in the range of from 50 to 500 nm, called nanoparticles, and a process for the preparation of such systems. The system is characterized in that the n... | 05/17/2011 |
| 7943173 | Pharmaceutical combinations of oxycodone and naloxone Disclosed in certain embodiments is a pharmaceutical composition comprising from 10 to 40 mg of oxycodone or a pharmaceutically acceptable salt thereof and 0.65 to 0.90 mg naloxone or a pharmaceutically acceptable salt thereof. ... | 05/17/2011 |
| 7935362 | Over-coated product including consumable center and medicament Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes one or more coatings having a medicament or agent. The coatings can further comprise one or more fat-based conf... | 05/03/2011 |
| 7923028 | High dose oral formulation of bisphosphonate and a process for making thereof The invention relates to a high dose oral formulation of bisphosphonates and to a process for the preparation of such formulations. ... | 04/12/2011 |
| 7919120 | Pharmaceutical safety dosage forms Pharmaceutical safety dosage forms are provided which include a pharmaceutical and an antagonist to the pharmaceutical. The safety dosage forms are such that the antagonist has no significant bioavailability when the pharmaceutical safety dosage form is administered... | 04/05/2011 |
| 7919115 | Orally disintegrating tablet compositions of lamotrigine The compositions of the present invention composition comprise a therapeutically effective amount of particles comprising lamotrigine, in combination with granules comprising a disintegrant, and a sugar alcohol and/or a saccharide. These compositions are useful in t... | 04/05/2011 |
| 7914811 | Brittle-coating, soft core dosage form The present invention provides an oral dosage form for delivering active agents having a soft core with an active agent particles, which have an average size of greater than about 50 μm, and a brittle shell encasing the soft core, wherein the weight ratio of drug p... | 03/29/2011 |
| 7901702 | Implantable or insertable medical devices for controlled delivery of a therapeutic agent The present invention is directed to novel implantable or insertable medical devices that provide controlled release of a therapeutic agent. According to an embodiment of the present invention, a therapeutic-agent-releasing medical device is provided, which comprise... | 03/08/2011 |
| 7897175 | Dosage forms comprising a CETP inhibitors and an HMG-CoA reductase inhibitor A dosage form comprises (1) a solid amorphous dispersion comprising a cholesterol ester transfer protein inhibitor and an acidic concentration-enhancing polymer and (2) an HMG-CoA reductase inhibitor. The solid amorphous dispersion and the HMG-CoA reductase inhibito... | 03/01/2011 |
| 7892527 | Acid-gas absorbing tablet and method of use An acid-gas absorbing tablet including in relatively sufficient proportions an adsorbent which may be activated carbon or silica gel or a mixture thereof, potassium carbonate, polyvinylpyrrolidinone, and potassium bicarbonate. A method of absorbing acid gases from a... | 02/22/2011 |
| 7887832 | Popping oral pharmaceutical compositions Disclosed are popping pharmaceutical compositions, which comprise OTC or prescription drug, and popping material. The popping material includes pressurized gas trapped within cavities of a pharmaceutically acceptable material in a manner that allows the gas to escap... | 02/15/2011 |
| 7887844 | Multiparticulate crystalline drug compositions having controlled release profiles A multiparticulate for controlled release of a drug comprises crystalline drug, a glyceride having at least one alkylate substituent of at least 16 carbon atoms, and a poloxamer, wherein at least 70 wt % of the drug in the multiparticulate is crystalline. ... | 02/15/2011 |
| RE42096 | Oral pulsed dose drug delivery system A multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate-release component and an enteric delayed-release component wherein (1) the enteric release coating has a defined minimum thickness and/or (2) there is ... | 02/01/2011 |
| 7879360 | Nanoparticulate compositions having a peptide as a surface stabilizer The present invention is directed to nanoparticulate active agent compositions comprising at least one peptide as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the inv... | 02/01/2011 |
| 7875292 | Orally disintegrable tablets An orally disintegrable tablet, of the present invention, which comprises (i) fine granules having an average particle diameter of 400 μm or less, which fine granules comprise a composition coated by an enteric coating layer, said composition having 10 weight % or ... | 01/25/2011 |
| 7875291 | Composition for managing diabetes, obesity, and hyperlipidemia and associated methods A nutritional supplement includes a first formulation including minerals: chromium polynicotinate, magnesium glycinate, manganese sulfate, selenium, vanadyl sulfate, zinc gluconate, copper gluconate, iodine, and boron; and vitamins: vitamins C, B1, B2, B3, B6, B12, ... | 01/25/2011 |
| 7875238 | Device for generating aqueous chlorine dioxide solutions The invention pertains to a device for generating aqueous chlorine dioxide solutions when the device is contacted with liquid water. The device comprises an alkali metal or alkaline earth metal chlorite, e.g., sodium chlorite, and a chemical reagent comprising an ac... | 01/25/2011 |
| 7867509 | Fast dissolving orally consumable films Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, met... | 01/11/2011 |
| 7850995 | Bioadhesive nanoparticulate compositions having cationic surface stabilizers Bioadhesive nanoparticulate compositions, comprising active agent particles and one or more cationic surface stabilizers, are described. The cationic surface stabilizers prevent aggregation of the nanoparticles and increase bioadhesion of the nanoparticles to biolog... | 12/14/2010 |
| 7842287 | Acid-gas absorbing tablet and method of use An acid-gas absorbing tablet including in relatively sufficient proportions an adsorbent which may be activated carbon or silica gel or a mixture thereof, potassium carbonate, polyvinylpyrrolidinone, and potassium bicarbonate. A method of absorbing acid gases from a... | 11/30/2010 |
| 7833547 | Ibuprofen and narcotic analgesic compositions Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising ibuprofen; a narcotic analgesic; colloidal silicon dioxide; a filler se... | 11/16/2010 |
| 7829120 | Trazodone composition for once a day administration The invention relates to a once a day formulation of trazodone or a trazodone derivative. The formulation contains trazodone or a trazodone derivative and a controlled release excipient so that, once administered orally, the trazodone or the trazodone derivative is ... | 11/09/2010 |
| RE41883 | Lotionized tissue products containing a pH balance compound for the skin A substrate treated with a lotion including a skin pH balancing compound and a base lotion. The pH balancing compound is preferably an organic acid, such as an alpha-hydroxy acid, an alpha-dihydroxy acid, or a beta-hydroxyacid, a combination of an organic acid and a... | 10/26/2010 |
| 7820201 | System for manufacturing controlled release dosage forms, such as zero-order release profile dosage form manufactured by three-dimensional printing The present invention includes controlled release dosage forms and methods of designing and manufacturing dosage forms to obtain specific release profiles, for example, zero-order release profiles, escalating release profiles or decreasing release profiles. The dosa... | 10/26/2010 |
| 7815940 | Gastric acid secretion inhibiting composition An oral pharmaceutical dosage form comprises pharmacologically effective amounts of an acid susceptible proton pump inhibitor or a salt thereof, an H2 receptor antagonist or a salt thereof and a pharmaceutically acceptable carrier. The dosage form is capable of rais... | 10/19/2010 |
| 7799345 | Preparation of injectable suspensions having improved injectability Injectable compositions having improved injectability. The injectable compositions include microparticles suspended in an aqueous injection vehicle having a viscosity of at least 20 cp at 20° C. The increased viscosity of the injection vehicle that constitutes the ... | 09/21/2010 |
| 7799340 | Pharmaceutical compositions for lipophilic drugs Stable solutions of lipophilic drugs, such as cyclosporin, forming a polar lipid self-emulsifying drug delivery system. The solutions can include lipophilic drugs, such as cyclosporin, dissolved in a polar lipid, such as having a C6-C12 fatty a... | 09/21/2010 |
| 7790200 | Formulation and process for drug loaded cores The present invention relates to a controlled release pellet of metoprolol and its pharmaceutically acceptable salts that uses a water soluble or a water swellable inert starting seed or core. ... | 09/07/2010 |
| 7785629 | Bicalutamide-adsorbates, process for preparing same, and pharmaceutical compositions thereof The present invention relates to an adsorbate, comprising an adsorbent and bicalutamide adsorbed on said adsorbent, a process for preparing same, and a pharmaceutical composition thereof. ... | 08/31/2010 |
| 7780987 | Controlled release dosage forms The invention provides stable controlled release monolithic coating compositions for use in coating pharmaceutical oral dosage forms comprising a polyglycol having a melting point greater than 55° C. and an aqueous dispersion of a neutral ester copolymer lacking fu... | 08/24/2010 |
| 7780989 | Process for the preparation of crystalline nano-particle dispersions A process for the preparation of a dispersion of crystalline nanoparticles in an aqueous medium is disclosed. Specifically, a first solution comprising a substantially water-insoluble substance in a water-miscible organic solvent is rapid mixed with an aqueous phase... | 08/24/2010 |
| 7772260 | Imidazo[2,1-]-1,3,4-thiadiazole sulfonamides This invention relates to compounds of Formula I and the use of compounds of Formula I as neuroprotective agents in the treatment of neuronal disorders of the central and peripheral nervous systems. Formula I: ... | 08/10/2010 |
| 7771740 | Medical devices containing copolymers with graft copolymer endblocks for drug delivery The present invention provides a medical device comprising a release region and a therapeutic agent disposed within or beneath the release region, and the release region includes a copolymer comprising a low Tg block and at least one graft copolymer endbl... | 08/10/2010 |
| 7771745 | Fast dissolving tablet and method of preparing the same The present invention provides a method for making a fast dissolving tablet. The method includes the steps of (a) preparing a first solution containing a hydrophilic polymer and a starch; (b) preparing a second solution containing a pharmaceutically active ingredien... | 08/10/2010 |
