User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 8188099 | Method of decreasing hepatotoxic side effects using Aadenosine receptor antagonists The invention is related to a method of decreasing hepatotoxic side effects using an A2B adenosine receptor antagonist and utility in the treatment of liver damage caused by undergoing hepatotoxic treatment, such as chemotherapy or radiation. The invention also rela... | 05/29/2012 |
| 8188105 | Therapeutic agent for inflammatory bowel disease comprising uracil derivative as active ingredient A therapeutic agent for inflammatory bowel disease contains, as an active ingredient, a uracil derivative or a pharmaceutically acceptable salt thereof, represented by formula (1) where the R1 and R2 groups are defined in the specification.... | 05/29/2012 |
| 8183285 | Therapeutic agent for irritable bowel syndrome and methods thereof The present invention provides a therapeutic agent and methods thereof for the treatment for irritable bowel syndrome. The agent comprises a compound represented by formula (I): wherein, R1 represents an optional... | 05/22/2012 |
| 8183206 | Drugs comprising combination of antithrombotic agent with pyrazolone derivative It is intended to provide drugs for treating ischemic diseases which are safe and have little side effects. Namely, drugs having a combination of an antithrombotic agent and a pyrazolone derivative defined in the description or its pharmaceutically acceptable salt. | 05/22/2012 |
| 8183295 | Pharmaceutical composition comprising a renin inhibitor, a calcium channel blocker and a diuretic The invention relates to a pharmaceutical composition comprising (i) a renin inhibitor, (ii) a calcium channel blocker (CCB), and a diuretic and to a method of using such composition for the treatment of cardiovascular disease. ... | 05/22/2012 |
| 8183232 | Therapeutic agent for hemorrhoidal disease An external preparation containing acetylsalicylic acid or its pharmaceutically acceptable salt as an active ingredient for treating anal diseases having therapeutic activity on hemorrhoids (internal hemorrhoid, external hemorrhoid), hemorrhoidal disease owing to an... | 05/22/2012 |
| 8168677 | Method for treatment of inflammatory bowel disease Method for therapeutic treatment of inflammatory bowel disease, including Crohn's disease, comprising administering to a patient in need thereof a therapeutically effective amount of a composition comprising a retinoid as an active ingredient to treat the inflammato... | 05/01/2012 |
| 8168669 | Therapeutic agent for inflammatory bowel disease and TNF-α production inhibitor Disclosed is an agent for use in the treatment or prevention of inflammatory bowel disease. Also disclosed is an agent for inhibiting the production of TNF-α. A therapeutic or prophylactic agent for inflammatory bowel disease comprising at least one amino acid sele... | 05/01/2012 |
| 8158658 | Heteroaromatic selective inhibitors of neuronal nitric oxide synthase Compounds selectively inhibiting neuronal nitric oxide synthase (nNos), such compounds of a formula wherein the variables are defined, herein. ... | 04/17/2012 |
| 8153693 | Compounds for the selective treatment of the intestinal immuno-inflammatory component of the celiac disease The present invention relates to amino-salicylic-aminophenyl compounds for use in the treatment of the inflammatory component of celiac disease. These compounds act by blocking the cytokines released in celiac disease and are specifically useful in the treatment of ... | 04/10/2012 |
| 8153691 | Method for preparing compositions for preventing or treating inflammatory bowel disease A method for preparing compositions, comprising docosahexaenoic acid (DHA) and optionally one or more fatty acids selected from the group consisting of eicosapentaenoic acid (EPA), arachidonic acid (ARA), linoleic acid (LA), and α-linoleic acid (ALA), that are admi... | 04/10/2012 |
| 8129430 | Method of reducing phosphate nephropathy in a mammal The present invention provides the invention provides methods of reducing phosphate nephropathy in a mammal suffering from impairment of renal function, including administering to the mammal an amount of citrate that is effective to reduce serum phosphorous concentr... | 03/06/2012 |
| 8124594 | Methods using phosphatidylserine, lysophosphatidylserine, and/or salts thereof to increase testosterone levels Methods using phosphatidylserine, lysophosphatidylserine, and/or salts thereof to increase testosterone levels in subjects in need thereof are disclosed herein. The methods can be useful for subjects having age related decline in testosterone, exercise induced decli... | 02/28/2012 |
| 8119656 | Inhibitors of the influenza virus non-structural 1 protein The present invention generally relates to compounds to treat viral infections and methods of their use. In particular, compounds of the present invention inhibit the activity of NS1 protein, thereby mitigating viral infection and, in particular, influenza virus inf... | 02/21/2012 |
| 8101606 | Neurofibromin pathway modulators The present invention encompasses methods for treating neurofibromatosis. ... | 01/24/2012 |
| 8097607 | Low dose rifalazil compositions The invention features low-dosage rifalazil compositions which are useful for the treatment of bacterial infections. ... | 01/17/2012 |
| 8097281 | Composition The present invention relates to dosage forms for oral administration of therapeutic formulations, adapted to provide immediate and/or sustained-release of therapeutic substances, particularly for oral administration of vitamins. There is provided a dosage form for ... | 01/17/2012 |
| 8093299 | Methods of treating bowel disorders The present invention relates to methods for treating bowel disorders using calcimimetics. ... | 01/10/2012 |
| 8088775 | Pharmaceutical composition for treating hair loss Disclosed is the use of 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid or its pharmaceutically acceptable salt for the reduction of hair loss; for hair regrowth, hair toning and hair growth; and for the treatment of female hirsutism. ... | 01/03/2012 |
| 8084491 | Treatments for wound healing The subject invention provides methods of promoting wound healing comprising the administration of a therapeutically effective amount of a composition comprising topiramate. Compositions may administered to a wound site via a salve, ointment, or as a component of a ... | 12/27/2011 |
| 8080579 | Compositions and methods for treatment of inflammatory bowel disease The present invention provides compositions and methods for treating inflammatory bowel disease. In particular, the present invention provides methods of therapeutically treating symptoms of inflammatory bowel disease using compositions comprising an angiotensin con... | 12/20/2011 |
| 8075883 | Use of adsorbent carbon microspheres for the treatment of irritable bowel syndrome Adsorbent carbon microspheres are administered to treat irritable bowel syndrome or symptoms associated with irritable bowel syndrome. ... | 12/13/2011 |
| 8071652 | Method of treating irritable bowel syndrome A treatment to differentially regulate the expression of genes related to irritable bowel syndrome is provided. ... | 12/06/2011 |
| 8071647 | Method for treatment of adhesion of the intestines Method for suppressing adhesion of the intestines or therapeutic treatment of adhesion of the intestines comprising administering to a patient in need thereof a therapeutically effective amount of 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]b... | 12/06/2011 |
| 8067446 | Methods for treating an ulcer of the small intestine and stomach A method for treating a digestive ulcer of the small intestine or stomach is disclosed with a non-purine xanthine oxidase inhibitor that is a carboxylic acid compound, wherein the non-purine xanthine oxidase inhibitor is a carboxylic acid compound of formula (I) or ... | 11/29/2011 |
| 8067471 | Composition comprising free amino acids A composition is described that can be used in prevention or treatment of patients having impaired gastro-intestinal tract function. The composition comprises free amino acids including about 9.0% to about 17.0% glutamic acid. Methods of treatment of impaired gastro... | 11/29/2011 |
| 8058316 | STAT3 inhibiting compositions and methods A composition may include a pharmaceutical carrier and an amount, therapeutically effective for the treatment of a retinal disease, of CLT-005 (1-acetyl-5-hydroxyanthracene-9,10 -dione), wherein the retinal disease is characterized by at least one of inflammation, a... | 11/15/2011 |
| 8058286 | Method for therapy of diarrhea-predominant irritable bowel disorders A method for therapy of diarrhea-predominant irritable bowel disorders comprising as an effective ingredient a morphinan derivative having a nitrogen-containing cyclic group or a pharmaceutically acceptable acid addition salt thereof is disclosed. The method for the... | 11/15/2011 |
| 8058281 | Use of adenine-derived compounds for the treatment of lupus The present invention is directed to a method of treating systemic lupus erythematosus comprising administering a compound of formula (I) wherein R1 is selected from the group consi... | 11/15/2011 |
| 8058303 | Pharmaceutical composition for external use Provided is a pharmaceutical composition for external use which includes the following components: 1) luliconazole and/or a salt thereof; 2) N-methyl-2-pyrollidone; and 3) benzyl alcohol and/or diester of a dibasic acid. The diester of the dibasic acid is a diethyl ... | 11/15/2011 |
| 8048922 | Compositions and methods for treating feline inflammatory bowel disease Compositions comprising eicosapentaenoic acid and docosahexaenoic acid in a ratio of from 1.2 to 2 are administered to felines to treat feline inflammatory bowel disease. ... | 11/01/2011 |
| 8048928 | Therapeutic agent for treating liver disease containing 2-amino-1,3-propanediol derivative as active ingredient, and method for treating liver disease A method for treating a liver disease such as hepatitis, comprising administering to a patient having the liver disease, an effective amount of a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure, and represented by the following formu... | 11/01/2011 |
| 8048924 | Methods and compositions employing 4-aminophenylacetic acid compounds The invention provides compositions comprising 4-APAA compounds and methods for treating disorders involving inflammation of the intestinal system, such as inflammatory bowel disease. The methods and compositions of the invention also include combinations of 4-APAA ... | 11/01/2011 |
| 8044071 | Method for reducing side effects of CBreceptor agonist therapy using a combination of a selective CBreceptor agonist and a selective CBreceptor antagonist The present application describes a method of treating pain with a combination of a CB2 cannabinoid receptor agonist and rimonabast. ... | 10/25/2011 |
| 8026282 | Phenoxyalkylcarboxylic acid derivatives in the treatment of irritable bowel syndrome A method of treating irritable bowel syndrome in a patient suffering therefrom comprising: administering an effective amount of a compound selected from compound 1, its metabolite 2 and pharmaceutically acceptable salts or esters thereof: | 09/27/2011 |
| 8021656 | Probiotics for gut neuromuscular functions The present invention relates to a method of treating gut pain or gut discomfort related or linked to gut muscular abnormalities comprising the step of administering to a human or an animal having gut pain or gut discomfort an effective amount of a selected probioti... | 09/20/2011 |
| 8022086 | Therapeutic agent for glomerular disease The present invention relates to a preventive and/or therapeutic agent for a glomerular disease containing, as active ingredients, pitavastatin or a salt thereof and candesartan cilexetil or a salt thereof. The agent of the present invention exhibits an excellent ef... | 09/20/2011 |
| 8008319 | Treatment of colorectal polyps with imidazoquinoline derivatives The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-ami... | 08/30/2011 |
| 8008349 | Stable pharmaceutical preparation comprising levothyroxine sodium, gelatin and fillers and which is free of organic solvent residues The invention relates to a pharmaceutical preparation comprising levothyroxine sodium, gelatine and fillers, which is free of organic solvent residues. ... | 08/30/2011 |
| 8003692 | Methods and compositions to inhibit edema factor and adenylyl cyclase Fluorene-based molecules and their derivatives are described in compositions for the treatment of intestinal fluid loss. ... | 08/23/2011 |