U.S. patents available from 1976 to present.
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Patent No. 6293874

User-operated amusement apparatus for kicking the user's buttocks

An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.

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Spivack, Phyllis G.


Primary examiner statistics: 780 patents; average approval time: 780 days
Assistant examiner statistics: 179 patents; average approval time: 664 days

Patents as Primary Examiner

1                      
NumberTitleIssue Date
8188099Method of decreasing hepatotoxic side effects using Aadenosine receptor antagonists
The invention is related to a method of decreasing hepatotoxic side effects using an A2B adenosine receptor antagonist and utility in the treatment of liver damage caused by undergoing hepatotoxic treatment, such as chemotherapy or radiation. The invention also rela...
05/29/2012
8188105Therapeutic agent for inflammatory bowel disease comprising uracil derivative as active ingredient
A therapeutic agent for inflammatory bowel disease contains, as an active ingredient, a uracil derivative or a pharmaceutically acceptable salt thereof, represented by formula (1) where the R1 and R2 groups are defined in the specification....
05/29/2012
8183285Therapeutic agent for irritable bowel syndrome and methods thereof
The present invention provides a therapeutic agent and methods thereof for the treatment for irritable bowel syndrome. The agent comprises a compound represented by formula (I): wherein, R1 represents an optional...
05/22/2012
8183206Drugs comprising combination of antithrombotic agent with pyrazolone derivative
It is intended to provide drugs for treating ischemic diseases which are safe and have little side effects. Namely, drugs having a combination of an antithrombotic agent and a pyrazolone derivative defined in the description or its pharmaceutically acceptable salt.
05/22/2012
8183295Pharmaceutical composition comprising a renin inhibitor, a calcium channel blocker and a diuretic
The invention relates to a pharmaceutical composition comprising (i) a renin inhibitor, (ii) a calcium channel blocker (CCB), and a diuretic and to a method of using such composition for the treatment of cardiovascular disease. ...
05/22/2012
8183232Therapeutic agent for hemorrhoidal disease
An external preparation containing acetylsalicylic acid or its pharmaceutically acceptable salt as an active ingredient for treating anal diseases having therapeutic activity on hemorrhoids (internal hemorrhoid, external hemorrhoid), hemorrhoidal disease owing to an...
05/22/2012
8168677Method for treatment of inflammatory bowel disease
Method for therapeutic treatment of inflammatory bowel disease, including Crohn's disease, comprising administering to a patient in need thereof a therapeutically effective amount of a composition comprising a retinoid as an active ingredient to treat the inflammato...
05/01/2012
8168669Therapeutic agent for inflammatory bowel disease and TNF-α production inhibitor
Disclosed is an agent for use in the treatment or prevention of inflammatory bowel disease. Also disclosed is an agent for inhibiting the production of TNF-α. A therapeutic or prophylactic agent for inflammatory bowel disease comprising at least one amino acid sele...
05/01/2012
8158658Heteroaromatic selective inhibitors of neuronal nitric oxide synthase
Compounds selectively inhibiting neuronal nitric oxide synthase (nNos), such compounds of a formula wherein the variables are defined, herein. ...
04/17/2012
8153693Compounds for the selective treatment of the intestinal immuno-inflammatory component of the celiac disease
The present invention relates to amino-salicylic-aminophenyl compounds for use in the treatment of the inflammatory component of celiac disease. These compounds act by blocking the cytokines released in celiac disease and are specifically useful in the treatment of ...
04/10/2012
8153691Method for preparing compositions for preventing or treating inflammatory bowel disease
A method for preparing compositions, comprising docosahexaenoic acid (DHA) and optionally one or more fatty acids selected from the group consisting of eicosapentaenoic acid (EPA), arachidonic acid (ARA), linoleic acid (LA), and α-linoleic acid (ALA), that are admi...
04/10/2012
8129430Method of reducing phosphate nephropathy in a mammal
The present invention provides the invention provides methods of reducing phosphate nephropathy in a mammal suffering from impairment of renal function, including administering to the mammal an amount of citrate that is effective to reduce serum phosphorous concentr...
03/06/2012
8124594Methods using phosphatidylserine, lysophosphatidylserine, and/or salts thereof to increase testosterone levels
Methods using phosphatidylserine, lysophosphatidylserine, and/or salts thereof to increase testosterone levels in subjects in need thereof are disclosed herein. The methods can be useful for subjects having age related decline in testosterone, exercise induced decli...
02/28/2012
8119656Inhibitors of the influenza virus non-structural 1 protein
The present invention generally relates to compounds to treat viral infections and methods of their use. In particular, compounds of the present invention inhibit the activity of NS1 protein, thereby mitigating viral infection and, in particular, influenza virus inf...
02/21/2012
8101606Neurofibromin pathway modulators
The present invention encompasses methods for treating neurofibromatosis. ...
01/24/2012
8097607Low dose rifalazil compositions
The invention features low-dosage rifalazil compositions which are useful for the treatment of bacterial infections. ...
01/17/2012
8097281Composition
The present invention relates to dosage forms for oral administration of therapeutic formulations, adapted to provide immediate and/or sustained-release of therapeutic substances, particularly for oral administration of vitamins. There is provided a dosage form for ...
01/17/2012
8093299Methods of treating bowel disorders
The present invention relates to methods for treating bowel disorders using calcimimetics. ...
01/10/2012
8088775Pharmaceutical composition for treating hair loss
Disclosed is the use of 2-[2-[4-[(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid or its pharmaceutically acceptable salt for the reduction of hair loss; for hair regrowth, hair toning and hair growth; and for the treatment of female hirsutism. ...
01/03/2012
8084491Treatments for wound healing
The subject invention provides methods of promoting wound healing comprising the administration of a therapeutically effective amount of a composition comprising topiramate. Compositions may administered to a wound site via a salve, ointment, or as a component of a ...
12/27/2011
8080579Compositions and methods for treatment of inflammatory bowel disease
The present invention provides compositions and methods for treating inflammatory bowel disease. In particular, the present invention provides methods of therapeutically treating symptoms of inflammatory bowel disease using compositions comprising an angiotensin con...
12/20/2011
8075883Use of adsorbent carbon microspheres for the treatment of irritable bowel syndrome
Adsorbent carbon microspheres are administered to treat irritable bowel syndrome or symptoms associated with irritable bowel syndrome. ...
12/13/2011
8071652Method of treating irritable bowel syndrome
A treatment to differentially regulate the expression of genes related to irritable bowel syndrome is provided. ...
12/06/2011
8071647Method for treatment of adhesion of the intestines
Method for suppressing adhesion of the intestines or therapeutic treatment of adhesion of the intestines comprising administering to a patient in need thereof a therapeutically effective amount of 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)carbamoyl]b...
12/06/2011
8067446Methods for treating an ulcer of the small intestine and stomach
A method for treating a digestive ulcer of the small intestine or stomach is disclosed with a non-purine xanthine oxidase inhibitor that is a carboxylic acid compound, wherein the non-purine xanthine oxidase inhibitor is a carboxylic acid compound of formula (I) or ...
11/29/2011
8067471Composition comprising free amino acids
A composition is described that can be used in prevention or treatment of patients having impaired gastro-intestinal tract function. The composition comprises free amino acids including about 9.0% to about 17.0% glutamic acid. Methods of treatment of impaired gastro...
11/29/2011
8058316STAT3 inhibiting compositions and methods
A composition may include a pharmaceutical carrier and an amount, therapeutically effective for the treatment of a retinal disease, of CLT-005 (1-acetyl-5-hydroxyanthracene-9,10 -dione), wherein the retinal disease is characterized by at least one of inflammation, a...
11/15/2011
8058286Method for therapy of diarrhea-predominant irritable bowel disorders
A method for therapy of diarrhea-predominant irritable bowel disorders comprising as an effective ingredient a morphinan derivative having a nitrogen-containing cyclic group or a pharmaceutically acceptable acid addition salt thereof is disclosed. The method for the...
11/15/2011
8058281Use of adenine-derived compounds for the treatment of lupus
The present invention is directed to a method of treating systemic lupus erythematosus comprising administering a compound of formula (I) wherein R1 is selected from the group consi...
11/15/2011
8058303Pharmaceutical composition for external use
Provided is a pharmaceutical composition for external use which includes the following components: 1) luliconazole and/or a salt thereof; 2) N-methyl-2-pyrollidone; and 3) benzyl alcohol and/or diester of a dibasic acid. The diester of the dibasic acid is a diethyl ...
11/15/2011
8048922Compositions and methods for treating feline inflammatory bowel disease
Compositions comprising eicosapentaenoic acid and docosahexaenoic acid in a ratio of from 1.2 to 2 are administered to felines to treat feline inflammatory bowel disease. ...
11/01/2011
8048928Therapeutic agent for treating liver disease containing 2-amino-1,3-propanediol derivative as active ingredient, and method for treating liver disease
A method for treating a liver disease such as hepatitis, comprising administering to a patient having the liver disease, an effective amount of a diarylsulfide or diarylether derivative having 2-amino-1,3-propanediol structure, and represented by the following formu...
11/01/2011
8048924Methods and compositions employing 4-aminophenylacetic acid compounds
The invention provides compositions comprising 4-APAA compounds and methods for treating disorders involving inflammation of the intestinal system, such as inflammatory bowel disease. The methods and compositions of the invention also include combinations of 4-APAA ...
11/01/2011
8044071Method for reducing side effects of CBreceptor agonist therapy using a combination of a selective CBreceptor agonist and a selective CBreceptor antagonist
The present application describes a method of treating pain with a combination of a CB2 cannabinoid receptor agonist and rimonabast. ...
10/25/2011
8026282Phenoxyalkylcarboxylic acid derivatives in the treatment of irritable bowel syndrome
A method of treating irritable bowel syndrome in a patient suffering therefrom comprising: administering an effective amount of a compound selected from compound 1, its metabolite 2 and pharmaceutically acceptable salts or esters thereof:
09/27/2011
8021656Probiotics for gut neuromuscular functions
The present invention relates to a method of treating gut pain or gut discomfort related or linked to gut muscular abnormalities comprising the step of administering to a human or an animal having gut pain or gut discomfort an effective amount of a selected probioti...
09/20/2011
8022086Therapeutic agent for glomerular disease
The present invention relates to a preventive and/or therapeutic agent for a glomerular disease containing, as active ingredients, pitavastatin or a salt thereof and candesartan cilexetil or a salt thereof. The agent of the present invention exhibits an excellent ef...
09/20/2011
8008319Treatment of colorectal polyps with imidazoquinoline derivatives
The invention relates to treating colorectal polyps and precancercerous colorectal changes by topical administration of immunomodulating drugs of the imidazoquinoline family, such as imiquimod (1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine), resiquimod (4-ami...
08/30/2011
8008349Stable pharmaceutical preparation comprising levothyroxine sodium, gelatin and fillers and which is free of organic solvent residues
The invention relates to a pharmaceutical preparation comprising levothyroxine sodium, gelatine and fillers, which is free of organic solvent residues. ...
08/30/2011
8003692Methods and compositions to inhibit edema factor and adenylyl cyclase
Fluorene-based molecules and their derivatives are described in compositions for the treatment of intestinal fluid loss. ...
08/23/2011
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