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Nutter, Nathan M.


Primary examiner statistics: 2245 patents; average approval time: 2244 days
Assistant examiner statistics: 633 patents; average approval time: 688 days

Patents as Assistant Examiner


1                      
NumberTitleIssue Date
4994554Probursin
A multi-functional mammalian peptide probursin isolated in purified form, produced synthetically or recombinantly can be used therapeutically for treatment of immune disorders and tumor inhibition....
02/19/1991
4973676Plasmids, genes and DNA expressing a bacillus thuringiensis protein toxic to coleoptera and bacteria transformed thereby
The invention comprises DNA expressing a Bacillus thuringiensis protein toxic to Coleoptera, as well as the gene which expresses the protein. Also included are plasmids which contain this DNA and non-Bacillus thuringiensis bacterium transformed by the DNA...
11/27/1990
4970298Biodegradable matrix and methods for producing same
This invention relates to a biodegradable collagen matrix having a pore size and morphology which enhances the healing of a wound. It further relates to a process for preparing the matrix. One embodiment of the invention comprises a biodegradable matrix w...
11/13/1990
4950712Polymers derived from crosslinked polystyrenes and dextrans, their methods of preparation and their applications for the analysis and purification of molecules of biological origin
These resins derived from a crosslinked styrene (co)-polymer, or from a crosslinked dextran, comprise a (co)-polymer chain which is substituted with one or more groups, which may be identical or different, belonging to the following categories: --Z--A
08/21/1990
4931498Immobilized artificial membranes
Methods and materials are described for the preparation of novel immobilized membrane compositions. The described compositions are useful for evaluating membrane association charcteristics of chemical compounds, and as a chromatographic support material f...
06/05/1990
4929670Polysaccharides containing aromatic aldehydes and their derivatization via amine-aldehyde interactions
A polysaccharide derivative having the structure Sacch--O--Z--Ar--CH.dbd.N--Y or ##STR1## where Sacch--O-- represents a polysaccharide molecule; Z is --(CH2)n -- or ##STR2## Ar is a divalent aromatic group; Y is (a) a ...
05/29/1990
4929671Allylic side chain-containing solid phase systems, processes for the preparation thereof and the use thereof in solid phase reactions
The present invention provides an allylic side chain-containing solid phase system, in which the allylic side chains are bound to a solid carrier material, of the general formula ##STR1## wherein F is a solid carrier material, R1 and R
05/29/1990
4927633Dispenser for delivering drug to livestock
A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a housing defining an internal space, (2) heat responsive means containing a beneficial agent in the spece, (3) means for increasing the amount of beneficial agen...
05/22/1990
4927879Method for solid phase membrane mimetics
A membrane mimetic structure having a hydrophilic outer portion and a hydrophobic inner portion is covalently bound to a surface having reactive functional groups. The membrane mimetic structure consists essentially of adjacent amphiphilic molecules indep...
05/22/1990
4927970Substituted 3-cyclobutene-1,2-dione intermediates
The present invention relates to novel intermediates of the formula ##STR1## wherein R is lower alkyl or cyclohexyl, and X is hydroxy or a conventional leaving group, and the use thereof in a process for the preparation of certain histamine H2
05/22/1990
4927813Method and composition for treating pediculosis capitis
A composition and method for removing head lice nits from a human are disclosed. The composition contains a therapeutically effective amount of formic acid in a pharmaceutically acceptable carrier. The composition is applied to the hair and scalp of a pat...
05/22/1990
4927968Chemical intermediates and process
The present invention relates to novel intermediates of the formula ##STR1## wherein R1 is hydrogen or lower alkyl and R is ##STR2## --CH2 OH or --CH2 X in which X is a conventional leaving group and Y is lower a...
05/22/1990
4925924Biocompatible synthetic and collagen compositions having a dual-type porosity for treatment of wounds and pressure ulcers and therapeutic methods thereof
A therapeutic method for treating pressure ulcers like decubitus ulcers with biodegradable collagen flake compositions and with biodegradable collagen sponge or sponge-like compositions. The products of the invention includes biodegradable collagen flake ...
05/15/1990
4923979Cellulose carbamate products of lowered carbamate content
The carbamate content of cellulose carbamate products is reduced by treating such products with solutions of a base, which solution also contains one or several alkali metal salts, particularly carbonates, sulfates, phosphates, borates and acetates....
05/08/1990
4918167Method of producing prepolymers from hydroxyalkyl lignin derivatives
A method of producing prepolymeric materials from lignin is disclosed. The method uses lignin which has been hydroxyalkyl modified, such that the lignin is substantially non-phenolic and solvent soluble and/or liquid. The modified lignin is reacted with m...
04/17/1990
4918161Low molecular weight pulmonary surfactant proteins
This invention relates to novel proteins useful for enhancing pulmonary surfactant activity, methods for obtaining said proteins and compositions containing one or more of the proteins....
04/17/1990
4916161Taste-masking pharmaceutical agents
The unpleasant taste of ibuprofen or other bad-tasting pharmaceuticals can be mediated via wet granulation using certain taste masking agents....
04/10/1990
4914151Resin-linker combination for the solid-phase synthesis of peptides and intermediates
The present invention relates to a novel polymeric carrier, a process for its production and its use for the preparation of peptides and their intermediates. The process comprises reacting chloromethylated polystyrene (cross-linked with divinylbenzene) wi...
04/03/1990
4911924Induction of antibiotic hypersensitivity in tetracycline-resistance microorganisms
Microorganisms carrying tetracycline-resistant determinants are hypersensitized to Sm- and 2-DOS- aminoglycoside antibiotics by exposure to subinhibitory amounts of tetracycline inducer....
03/27/1990
4911731Process and composition for dyeing hair utilizing an anionic polymeric/cationic polymer complex
A process and composition for dyeing hair involving the precipitation of an anionic polymeric dye by means of a cationic polymer preferably in the presence of a surfactant and particularly an amphoteric surfactant....
03/27/1990
4910014Teeth cleaning composition with semiconductive titanium oxide
A dentifrice with ordinary components and a powder of n-type semiconductor of titanium dioxide having a purity of at least 99.5% and particle diameter smaller than about 0.04 μm and forming 5 to 10% by weight of said dentifrice, the ordinary components i...
03/20/1990
4908203Method for inducing HIV neutralizing antibodies using an internal image idiotope
The present invention contemplates a method for inducing a HIV neutralizing immune response using an OKT4A antibody molecule homolog as an immunogen. Vaccines for practicing an immunization method of this invention are also described....
03/13/1990
4908404Synthetic amino acid-and/or peptide-containing graft copolymers
A water soluble cationic peptide-containing graft copolymer exhibiting a number average molecular weight of from about 30,000 to about 500,000 are provided comprising: (a) a polymeric backbone containing or capable of modification to include free primary ...
03/13/1990
4906579New catalytically oxidized polyglucosic units and methods of making same leading to aldehyde groups on the C-6 position of polyglucosic product and new products therefrom
A method to selectively oxidize a polyglucose, on the oxygen of the hydroxy groups of the C-6 position of the glucose rings, while substantially maintaining the degree of polymerization of the polyglycosidic units, comprising heating a 6-sulfonyl polygluc...
03/06/1990
4904645Environmentally safe, broad spectrum insecticide
A combination of pyrethrum and fatty acid salt materials has been formulated which produces a stable, commercially useful, and environmentally safe pesticide. The specific composition comprises an aqueous solutioon having a pH within the range of 7.5 to 8...
02/27/1990
4904698Eyelid cleansing composition
A non-irritating liquid cleansing composition is described for cleansing eyelids. The composition includes an aqueous solution of Miranol MS-2 present in a concentration of 7-10%; PEG-15 tallow polyamine present in a concentration of 0.1-0.5%; sodium chlo...
02/27/1990
4900780Acellular resuscitative fluid
An acelluar resuscitative fluid, useful as an artificial blood or blood substitute, is prepared from a modified, high molecular weight starch or a tetronic polyol prepared by the interaction of ethylenediamine and ethylene or propylene oxides, which are c...
02/13/1990
4900548Use of diethylcarbamazine to enhance antigen-antibody and antigen-host immune cell interactions
This invention relates to the use of diethylcarbamazine (DEC), its analogs, homologs, and pharmaceutically acceptable salts thereof as an antiviral agent. This invention further relates to the use of DEC in in vivo diagnosis to increase antibodies to a pa...
02/13/1990
4897445Method for synthesizing a peptide containing a non-peptide bond
This invention features a method for the solid phase synthesis of non-peptide bonds (CH2 --NH) in polypeptide chains. These polypeptides are synthesized by standard procedures and the non-peptide bond synthesized by reacting an amino aldehyde a...
01/30/1990
4897467Nitrilophoric EDA-adsorbents
An adsorbent that comprises a solid phase for the isolation and immobilization of proteins by adsorption from a liquid phase is characterized in that it consists of a hydrophilic polymer network with covalently bound ligands of the formula --Y--X--R, in w...
01/30/1990
4895896Contact lens having improved eye compatibility
Contact lens comprising an eye-compatible surface on which monoclonal antibodies or fragments of antibodies are immobilized, the N-terminal ends of which are directed against mucous substances of the human ocular tear film....
01/23/1990
4895884Rubber containing microencapsulated antidegradants
There is disclosed the use of microencapsulated antidegradants in rubber and a process for the production of microencapsulated antidegradants. More specifically, this invention is directed to the cellulose acetate microencapsulation of para-phenylene diam...
01/23/1990
4895932Method for determining cardiodilatin and fragments thereof and antibodies useful in determination of cardiodilatin and its fragments
This invention teaches a method for determining the hormone cardiodilatin active fragments thereof, well as antibodies thereto....
01/23/1990
4892724Tartar inhibiting oral compositions and method
Oral compositions and a method for inhibiting tartar on teeth are disclosed herein, said compositions are characterized by the presence of a fluoride source, a dental abrasive, and an anticalculus agent which is an admixture of at least one phosphorus-con...
01/09/1990
4892725Tartar inhibition on teeth
Oral compositions and a method for inhibiting dental calculus are disclosed herein, said compositions are characterized by the presence of a flouride source, a dental abrasive, and an anticalculus agent of at least two polymers selected from homopolymers ...
01/09/1990
4892737Composition and method for enhancing permeability of topical drugs
A composition and method for enhancing permeability of topical drugs wherein the agent which enhances the permeability of the drug is selected from the group consisting of (1) a choline ester having the formula: [CH3 (CH2)n --C...
01/09/1990
4891404Biodegradable graft copolymers
A nucleophilic displacement reaction is used to prepare biodegradable thermoplastic copolymers exhibiting a high capacity for stabilizing biodegradable blends of polysaccharides and synthetic thermoplastic polymers. The graft copolymers are characterized ...
01/02/1990
4891218Rodenticide bait block
This invention relates to parafinized rodenticide bait blocks in general and, more specifically to the actual form of these bait blocks. The invention concerns itself with the physical construction and shape of the block and will provide a more effective roden...
01/02/1990
4889722Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator
Postsurgical adhesion formation is inhibited by the topical administration to the site of surgical trauma of a composition comprising tissue plasminogen activator....
12/26/1989
4889916Protein label and drug delivery system
A bridging molecule carrying a drug, or a label such as a fluorophore, which adds across disulfide bonds of molecules, particularly proteins, and methods of manfacturing and using the bridging molecules, are disclosed. The bridging molecule is reactive wi...
12/26/1989
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