Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 6316003 | Tat-derived transport polypeptides This invention relates to delivery of biologically active cargo molecules, such as polypeptides and nucleic acids, into the cytoplasm and nuclei of cells in vitro and in vivo. Intracellular delivery of cargo molecules according to this invention is accomp... | 11/13/2001 |
| 6274551 | Cytotoxic and antiviral compound Kalahide F, of formula I below, may be isolated from a sacoglossan. The compound may be used in the manufacture of pharmaceutical compositions or in the treatment of tumors or viral conditions. ##STR1##... | 08/14/2001 |
| 6258552 | Estimation of change in bone mineral density and diagnosis of osteoporosis A method for estimation of change in bone mineral density or a method for diagnosis of osteoporosis, comprising the step of measuring change in a concentration of soluble interleukin-6 receptor in a blood sample, by for example, sandwich assay or competit... | 07/10/2001 |
| 6258807 | Method for treating pain The present invention provides a method for treating pain comprising administering an analgesic dosage of olanzapine to an animal in need of such treatment.... | 07/10/2001 |
| 6232350 | Preparation and method for the treatment and prevention of dimentia disorders A preparation for the treatment and/or prevention of dementia disorders, especially disorders due to regressive cellular changes. A close of at least one steroidal antagonist is included as the active agent. A mixture of such substances can also be applie... | 05/15/2001 |
| 6228383 | Use of fatty acid esters as bioadhesive substances Use of fatty acid esters as bioadhesive substances. The fatty acid esters have molecular weights below about 1000 dalton and the fatty acid component of the fatty acid ester is a saturated or unsaturated fatty acid having a total number of carbon atoms of... | 05/08/2001 |
| 6225299 | Hormonal agent for skin treatment The pharmaceutical composition, especially for treating skin with seborrhea, Acne vulgaris and androgonically conditioned alopecia, contains a hormonal agent including the gestogen, dienogest, or a combination of dienogest and an estrogen, as active ingre... | 05/01/2001 |
| 6218435 | Reduction of hair growth A method of reducing hair growth in a mammal includes applying, to an area of skin from which reduced hair growth is desired, a dermatologically acceptable composition containing a suppressor of the metabolic pathway for the conversion of glucose to acety... | 04/17/2001 |
| 6217873 | Polyoxime compounds and their preparation Provided by this invention are essentially homogeneous, defined compositions of matter and hetero-polyoximes of defined structure comprising a baseplate structure having a plurality of oxime bonds, wherein each oxime bond links a specifically active molec... | 04/17/2001 |
| 6184030 | Biologically-active polymers This invention relates to biologically-active polymers that are useful for analyte detection and isolation and delivery of substances. The biologically-active polymers are capable of specifically and reversibly binding to analytes, including molecules and... | 02/06/2001 |
| 6184205 | GRB2 SH3 binding peptides and methods of isolating and using same Peptides having general and specific binding affinities for the Src homology region 3 (SH3) domains of proteins are disclosed in the present invention. In particular, SH3 binding peptides have been isolated from phage-displayed random peptide libraries wh... | 02/06/2001 |
| 6183772 | Doped colorimetric assay liposomes The present invention provides compositions comprising colorimetric assay liposomes. The present invention also provides methods for producing colorimetric liposomes and calorimetric liposome assay systems. In preferred embodiments, these calorimetric lip... | 02/06/2001 |
| 6180135 | Three-dimensional colorimetric assay assemblies A direct assay is described using novel three-dimensional polymeric assemblies which change from a blue to red color when exposed to an analyte, in one case a flue virus. The assemblies are typically in the form of liposomes which can be maintained in a s... | 01/30/2001 |
| 6177405 | Cyclic analogs of tuftsin The useful cyclic peptides cyclo[Thr-Lys-Pro-Arg-Gly] and cyclo[Thr-Lys-Pro-Arg-Asp] are disclosed.... | 01/23/2001 |
| 6177451 | Epibatidine and derivatives thereof as nicotine cholinergic receptor agonists The present invention provides methods of treatment utilizing pharmaceutical compositions comprising an effective nicotine agonist amount of epibatidine (1) or a synthetic 7-azabicyclo[2.2.1]-heptane or heptene derivative thereof, and a pharmaceutically a... | 01/23/2001 |
| 6174890 | Anti-stress, anti-impairment and anti-aging drug and process for manufacturing thereof The invention relates to a new pharmacotherapeutical strategy, to an anti-stress, anti-impairment and anti-aging drug and to a process for its manufacturing. The drug has an etio-pathogenic and homeostatic action, was preclinically tested and clinically c... | 01/16/2001 |
| 6172197 | Methods for producing members of specific binding pairs A member of a specific binding pair (sbp) is identified by expressing DNA encoding a genetically diverse population of such sbp members in recombinant host cells in which the sbp members are displayed in functional form at the surface of a secreted recomb... | 01/09/2001 |
| 6166085 | Method of producing analgesia The invention relates to methods of producing analgesia, particularly in the treatment-of-acute and persistent pain and neuropathic pain. The compound 2(ethylamino)-N-(3-hydroxy-2,6-dimethylphenyl) acetamide, or 3-hydroxymonoethylglycinexylidide (3-hydrox... | 12/26/2000 |
| 6162820 | Method for removing parasites and in particular ectoparasites of vertebrates, in particular of mammals, and compositions for the implementation of this method Methods for removing parasites and in particular ectoparasites of vertebrates, in particular of mammals, and compositions for the implementation of this method. Methods for removing parasites of vertebrates, and in particular arthropods, mainly insects an... | 12/19/2000 |
| 6162827 | Treatment of negative and cognitive symptoms of schizophrenia with D-serine The amino acid glycine in an administered amount of above 0.4 g/Kg/day is used for treating symptoms of psychosis and of schizophrenia.... | 12/19/2000 |
| 6153743 | Lithographic mask design and synthesis of diverse probes on a substrate Systems and methods of synthesizing probes on a substrate are provided. One or more shift reticles are utilized to uniformly add monomers to the substrate at specified locations. The shift reticles are shifted relative to the substrate between monomer add... | 11/28/2000 |
| 6153731 | Dehydrodidemnin B Dehydrodidemnin B with useful biological activity has formula (1). It can be isolated from natural sources or synthesized, and it forms active derivatives. ##STR1##... | 11/28/2000 |
| 6147051 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction Compounds having antagonistic activity on endothelin receptors can be effectively used for prophylaxis and/or treatment of hypofunction of organs which occurs in their surgery or transplant.... | 11/14/2000 |
| 6143305 | Antigenically modified polypeptides composition Endogenous and exogenous proteins, and fragments thereof, are chemically modified outside the body of an animal so that when injected into the animal they produce more antibodies against the unmodified protein than would injection of the unmodified protei... | 11/07/2000 |
| 6143782 | Anti-inflammatory and anti-asthma treatment with reduced side effects This invention relates to a method for selecting PDE IV inhibitors which have a salutory therapeutic index, and to compounds having these properties.... | 11/07/2000 |
| 6140359 | Injectable composition A pharmaceutical formulation of paclitaxel (also known as taxol) and polyethoxylated castor oil is disclosed to be relatively acidified to a pH of less than 8.1 and preferably within a pH range of 5 to 7, inclusively. Ethanol is optionally included in the... | 10/31/2000 |
| 6140371 | Therapeutic uses of known ester and amide compounds A number of new therapeutic uses have been found for compounds such as known local anesthetics which are quite different from the present therapeutic uses of these drugs. The uses include, for example; modulating lymphocytes, macrophages and other immune ... | 10/31/2000 |
| 6140099 | Method of delaying fetal membrane rupture by inhibiting matrix metalloproteinase-9 activity The invention relates to compositions and methods for delaying the onset of fetal membrane rupture in a human. The method comprises administering to the human a metalloproteinase-9 inhibitor in an amount effective to delay the onset of fetal membrane rupt... | 10/31/2000 |
| 6140373 | Propofol composition The present invention is directed to a sterile pharmaceutical composition comprising a propofol containing oil-in-water emulsion formulation having as an antimicrobial agent, a member selected from the group consisting of benzyl alcohol and ethylene diami... | 10/31/2000 |
| 6136862 | Cerebral function improving agents A cerebral function improving agent containing as the active ingredient a compound represented by the following formula: ##STR1## wherein R2 represents a hydrogen atom when R1 is a hydroxyl group; or R1 or R1 | 10/24/2000 |
| 6137004 | Processes for recovering citric acid Described are preferred processes for recovering citric acid from a medium in which it is contained. The citric acid is recovered both effectively and in a form which is readily purifiable. In one preferred process, the citric acid-containing medium is co... | 10/24/2000 |
| 6127133 | Automated analysis equipment and assay method for detecting cell surface protein function using same Automated drug screening method and a method of studying receptor and ion-channel activity are provided.... | 10/03/2000 |
| 6126916 | Radiometal-binding peptide analogues Novel metal binding ligands are disclosed that may be coupled to peptides for use in methods of diagnosis and therapy. Peptides containing the ligands are produced using a method wherein ligand introduction or cyclization can be conducted at any point dur... | 10/03/2000 |
| 6127519 | Calcitonin derivatives Peptides useful in the regulation of calcium metabolism are disclosed. Also disclosed are pharmaceutical compositions of matter containing such peptides as well as a method for the regulation of calcium metabolism in a patient in need of such treatment. T... | 10/03/2000 |
| 6124101 | Recombinant thrombin receptor and related pharmaceuticals The DNA encoding the cell surface receptor for thrombin has been cloned and sequenced. The availability of this DNA permits the recombinant production of thrombin receptor which can be produced at cell surfaces and is useful in assay systems both for the ... | 09/26/2000 |
| 6120777 | High fluorescence specific immune enhancing factor and methods of use for same The present invention relates to a malondialdehyde-acetaldehyde adduct which acts as a specific immune-enhancing factor. In addition to its highly specific and immunogenic properties, the factor is highly fluorescent. It has an excitation frequency of abo... | 09/19/2000 |
| 6117982 | Conjugates of microbeads and antibodies specific for T lymphocytes and their use as in vivo immune modulators Several forms of immunoregulatory substances are derived from monoclonal antibodies (MAbs) that are specific for a T cell surface antigen, such as CD3, TCR, CD4, or CD8 on T cells. The substances include: a mixture of F(ab')2 fragments (or othe... | 09/12/2000 |
| 6114508 | Cocaethylene immunogens and antibodies The ethyl ester of derivatives of benzoyl ecgonine are provided having a linking group at the para position of the benzoyl group. The derivatives are used to bond to immunogenic polypeptides for production of antisera and monoclonal antibodies. The antise... | 09/05/2000 |
| 6114303 | Hemoglobin therapy in hemodialysis Low doses of stroma-free diaspirin cross-linked hemoglobin are administered to patients undergoing hemodialysis, to achieve hemostabilization and avoid hypotensive episodes in susceptible patients. Hemoglobin therapy when implemented prophylactically in h... | 09/05/2000 |
| 6113887 | Toothpaste composition There is disclosed a toothpaste composition containing: (1) a water-soluble bactericide selected from the group consisting of pyridinium compounds, quaternary ammonium compounds and biguanide compounds in an amount of 0.001% to 5.0% by weight, based on th... | 09/05/2000 |
