Did You Know...
...that while attempting to develop a super strong glue, 3M employee Spencer Silver accidentally developed a glue that was so weak it would barely hold two pieces of paper together? However, his colleague Art Fry needed the glue. Fry sang with his church choir and marked the pages of his hymnal with small scraps of paper that often fell out. He used Silver's glue to hold the papers in place. Today we call this invention Post-it Notes.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 6423527 | Sphingosine-1-phosphate lyase polypeptides, polynucleotides and modulating agents and methods of use therefor Compositions, methods and kits for diagnosing and treating cancer are provided. Therapeutic compositions may comprise agents that modulate the expression or activity of a springiness-1-phosphate lease (SPL). Such compositions may be administered to a mamm... | 07/23/2002 |
| 6420177 | Method for strain improvement of the erythromycin-producing bacterium The present invention relates to a method of improving the strain used for the production of erythromycin through the disruption of the melA gene.... | 07/16/2002 |
| 6403349 | Elongase gene and uses thereof The subject invention relates to the identification of a gene involved in the elongation of polyunsaturated fatty acids (i.e., "elongase") and to uses thereof. In particular, elongase is utilized in the conversion of gamma linolenic acid (GLA) to dihomoga... | 06/11/2002 |
| 6395530 | LLG polypeptides of the triacylglycerol lipase family, and compositions and methods for their use in enzymatic hydrolysis, and protein and gene therapies Lipoprotein Lipase like polypeptides, nucleic acids encoding said polypeptides, antisense sequences, and antibodies to said polypeptides are disclosed. Also disclosed are methods for the preparation of said polypeptides in a recombinant system and for the... | 05/28/2002 |
| 6392024 | Tenebrio antifreeze proteins A novel class of thermal hysteresis (antifreeze) proteins (THP) that have up to 100 times the specific activity of fish antifreeze proteins has been isolated and purified from the mealworm beetle, Tenebrio molitor. Internal sequencing of the proteins, lea... | 05/21/2002 |
| 6391605 | Modified phytases A process for the production of a modified phytase with a desired property improved over the property of the corresponding unmodified phytase is disclosed, as well as modified phytases, polynucleotides encoding modified phytases, and animal feed including... | 05/21/2002 |
| 6387667 | Process for producing cytidine diphosphate choline A process for producing cytidine diphosphate choline is provided. The process comprises carrying out an enzymatic reaction using microorganisms having the enzyme activities of cytidine-5'-triphosphate synthetase (pyrG), cholinephosphate cytidylyltransfera... | 05/14/2002 |
| 6383769 | Polypeptides having ଲ-fructofuranosidase activity Disclosed are a polypeptide having a ଲ-fructofuranosidase activity obtainable by the expression of a microbial gene, a DNA encoding the polypeptide, a transformant obtained by introducing the DNA into an appropriate host, a process for producing the... | 05/07/2002 |
| 6358722 | Heat tolerant phytases The present invention relates to heat tolerant phytases and DNA sequences which code therefor. The phytases are useful in hydrolyzing phytate to inositol and inorganic phosphates. The phytases are valuable feed additives.... | 03/19/2002 |
| 6352847 | Ammonia elimination liquid reagent The invention provides an ammonia elimination reagent in solution, comprising a thermo-resistant isocitrate dehydrogenase with prominent stability under conditions at high alkaline pHs. For example, the isocitrate dehydrogenase is preferably derived from ... | 03/05/2002 |
| 6350598 | MurD The invention provides MurD polypeptides and DNA (RNA) encoding MurD polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing MurD polypeptides to screen for antibacterial compounds.... | 02/26/2002 |
| 6350597 | Riboflavin synthase genes and enzymes and methods of use Through function complementation of E. coli auxotrophs, the ultimate and pentultimate enzymes of the spinach riboflavin biosynthetic pathway have been cloned, namely, lumazine synthase (LS) and riboflavin synthase (RS). This invention relates to the isola... | 02/26/2002 |
| 6350602 | Cloning and expression of phytase from aspergillus A nucleotide sequence encoding phytase has been isolated and cloned. The coding sequence has been inserted into an expression construct which in turn has been inserted into a vector capable of transforming a microbial expression host. The transformed micr... | 02/26/2002 |
| 6346607 | APAF-1 an activator of caspase-3 Novel polypeptides, designated Apaf-1, which are capable of modulating apoptosis are provided. Compositions including Apaf-1 chimeras, nucleic acid encoding Apaf-1, and antibodies to Apaf-1 are also provided.... | 02/12/2002 |
| 6344350 | Method for degradation of pinenes by bacillus isolates A novel isolate of Bacillus isolated from white pine is described. The isolate is used to produce monoterpene derivatives. Also described is a pinene hydroxylase enzyme from the isolate. The enzyme is a general allylic oxidizer.... | 02/05/2002 |
| 6331428 | Hexulose phosphate isomerase gene Hexulose phosphate synthase was purified from Mycobacterium gastri to determine an amino acid sequence of the enzyme. Oligonucleotide primers to be used for PCR were synthesized on the basis of obtained amino acid sequence information. A DNA fragment, whi... | 12/18/2001 |
| 6329191 | DNA encoding recombinant coffee bean alpha-galactosidase A recombinant DNA encoding coffee bean -galactosidase permits the production of purified forms of this protein. The protein is useful in converting human Type B red blood cells into cells physiologically similar to Type O red blood cells. The avail... | 12/11/2001 |
| 6323017 | Platelet activating factor acetylhydrolase, and gene thereof The present invention relates to an isolated human protein having platelet activating factor acetylhydrolase activity.... | 11/27/2001 |
| 6323013 | Lumazine synthase and riboflavin synthase Through function complementation of E. coli auxotrophs, the ultimate and pentultimate enzymes of the spinach riboflavin biosynthetic pathway have been cloned, namely, lumazine synthase (LS) and riboflavin synthase (RS). This invention relates to the isola... | 11/27/2001 |
| 6315996 | Topical lysostaphin therapy for staphylococcus ocular infections A method has been discovered for using lysostaphin as an effective antibiotic for topical treatment of Staphylococcus corneal infections (keratitis). Lysostaphin applied topically to the cornea by eye drops killed bacteria within the cornea; lysostaphin r... | 11/13/2001 |
| 6307019 | Axin gene and uses thereof This invention provides an isolated nucleic acid which encodes Axin. This invention further provides an isolated nucleic acid which encodes a polypeptide comprising the amino acid sequence of Axin. This invention further provides a purified wildtype or mu... | 10/23/2001 |
| 6306630 | Aspergillus porphobilinogen synthases and nucleic acids encoding same The present invention relates to Aspergillus porphobilinogen synthases and isolated nucleic acid fragments comprising nucleic acid sequences encoding the porphobilinogen synthases as well as nucleic acid constructs, vectors, and recombinant host cells com... | 10/23/2001 |
| 6306634 | Esterase gene and its use An isolated esterase gene coding for an esterase capable of causing asymmetric hydrolysis of an organic carboxylic acid ester of a cyclopentenolone of formula I; ##STR1## wherein R1 is C1 -C10 alkyl, C2 -C1... | 10/23/2001 |
| 6306639 | Genetically modified cyanobacteria for the production of ethanol, the constructs and method thereof The invention relates to the genetic modification of Cyanobacteria for the production of ethanol, and more particularly, to the genetic modification of Cyanobacteria by incorporating the genetic information encoding for pyruvate decarboxylase (pdc) and al... | 10/23/2001 |
| 6300112 | ଲ-xylosidase, nucleotide sequence encoding it, and use thereof A nucleotide sequence is provided which encodes a peptide having ଲ-xylosidase activity and exhibits at least 30% amino acid identity with the amino acid sequence shown in SEQ ID NO. 1 and described in SEQ ID NO. 3 or hybridises under stringent condi... | 10/09/2001 |
| 6300114 | Sequences of xylanase and xylanase expression vectors The production of thermostable xylanses having bacterial origin is described. These compositions are useful for modifying plant biomass and for enzyme-aided bleaching of wood pulp.... | 10/09/2001 |
| 6291221 | Heat tolerant phytases The present invention relates to heat tolerant phytases and DNA sequences which code therefor. The phytases are useful in hydrolyzing phytate to inositol and inorganic phosphates. The phytases are valuable feed additives.... | 09/18/2001 |
| 6284504 | Human DNA ligase III A human DNA Ligase III polypeptide and DNA (RNA) encoding such polypeptide and a procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide via gene therapy for the treatment ... | 09/04/2001 |
| 6281333 | Human galectin homolog The present invention provides a polynucleotide which identifies and encodes a novel human galectin-8. The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding human galectin-8. The ... | 08/28/2001 |
| 6280972 | Activator for methanol dehydrogenase and gene thereof A cell which is introduced with a DNA coding for a protein defined in the following (A) or (B): (A) a protein which has the amino acid sequence of SEQ ID NO: 2 shown in Sequence Listing; (B) a protein which has the amino acid sequence of SEQ ID NO: 2 shown in ... | 08/28/2001 |
| 6274357 | Enzymatic esterification process Aliphatic, saturated or unsaturated, straight or branched chain C2-C24 monocarboxylic acids and polyhydric alcohols, particularly glycerol are selectively reached to monoesters in the presence of an enzyme which comprises potato lipid acyl hydrolase. The ... | 08/14/2001 |
| 6274361 | pth The invention provides pth polypeptides and polynucleotides encoding pth polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing pth polypeptides to screen for antibacterial compounds.... | 08/14/2001 |
| 6274365 | Pharmaceutical composition having an endoproteolytic activity The invention is based on the finding that furin belongs to a family of endoproteolytically active enzymes and relates to a process for the in vitro cleavage of a protein by treating the protein in the presence of Ca2 + ions with furin or a fur... | 08/14/2001 |
| 6265544 | Adipocyte-specific protein homologs The present invention relates to polynucleotide and polypeptide molecules for zsig37, a novel member of the family of proteins bearing a collagen-like domain and a globular domain. The polypeptides, and polynucleotides encoding them, are involved in dimer... | 07/24/2001 |
| 6265557 | ABO histo-blood group O alleles of the baboon This invention relates to histo-blood group O alleles of baboon. The major O allele retains identifying sequence characteristics of the baboon A allele. Other alleles, including a B-like allele, are also disclosed herein. The O alleles of baboon are close... | 07/24/2001 |
| 6265547 | Cell junction PDZ protein The invention provides a human cell junction PDZ protein (CJPDZ) and polynucleotides which identify and encode CJPDZ. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods fo... | 07/24/2001 |
| 6261820 | Fibronolytically active polypeptide A fibrinolytically active metalloproteinase polypeptide (called "novel acting thrombolytic") which is useful for blood clot lysis in vivo and methods and materials for its production by recombinant expression are described.... | 07/17/2001 |
| 6258587 | Recombinant, sequence-modified L. johnsonii bacteria which produce only L(+)-lactate Recombinant strains of L. johnsonii which have capacities of surviving passage through the intestine, adhering to human intestinal cells and increasing phagocytosis of macrophages and which have a sequence of gene coding which is an L. johnsonii strain se... | 07/10/2001 |
| 6255464 | Mad-related genes in the human Five human genes related to the Mad gene of Drosophila were identified. One of these genes (Smad2) was found to reside at chromosome 18q21, adjacent to a previously described member of this family called DPC4 (Smad4). Smad2 was found to be somatically mut... | 07/03/2001 |
| 6251585 | Assay and reagents for identifying anti-proliferative agents The present invention makes available assays and reagents for identifying anti-proliferative agents, such as mitotic and meiotic inhibitors. The present assay provides a simple and rapid screening test which relies on scoring for positive cellular prolife... | 06/26/2001 |
