Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
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| Number | Title | Issue Date |
| 5627211 | Cyclohexyl amine derivatives and their use as tachykinin antagonists Compounds of formula (I), and salts and prodrugs thereof wherein X, R2, R3, R4, R5, R7 and R8 are defined herein, are tachykinin receptor antagonists. ##STR1##... | 05/06/1997 |
| 5605932 | Opiate receptor ligands Compounds of Formula 1 bind opioid receptors: which binds to the opioid receptor: ##STR1##... | 02/25/1997 |
| 5510523 | Process for the preparation of acetic acid A process for preparing acetic acid from methanol and carbon monoxide or a mixed gas of carbon monoxide with hydrogen, which process comprises contacting methanol with a gaseous component selected from a group consisting of carbon monoxide and a mixed gas... | 04/23/1996 |
| 5491172 | N-acyl sulfamic acid esters (or thioesters), N-acyl sulfonamides, and N-sulfonyl carbamic acid esters (or thioesters) as hypercholesterolemic agents The present invention is directed to compounds useful for the regulation of cholesterol of Formula I, methods for using them and pharmaceutical compositions thereof, ##STR1## wherein X and Y are oxygen, sulfur, or (CR'R")n wherein n is 1 t... | 02/13/1996 |
| 5476846 | Substituted sulfonamides, process of preparation and medicines containing same The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts, complexes, esters and amides thereof, represented by the formula ##STR1## which is defined herein. Said compounds find application as anti-thr... | 12/19/1995 |
| 5466861 | Bridged bicyclic aromatic compounds and their use in modulating gene expression of retinoid receptors Bridged bicyclic aromatic compounds are provided having the structure ##STR1## wherein R1, R2, R3, R4, R5 and n are as defined herein. The novel compounds are useful for modulating gene expression of ... | 11/14/1995 |
| 5457172 | (Meth)acrylic compounds, process for their preparation and their application to the synthesis of new polymers These compounds are denoted by the following formula (I): ##STR1## in which: Z denotes H or a linear or branched alkyl radical, X denotes O or S, each of A and B independently denotes an alkylene radical, it being possible for this radical to be substitut... | 10/10/1995 |
| 5457228 | Method for producing lower alkyl acetate A method for producing a lower alkyl acetate in which undesirable polymerization of the starting material of olefin and deterioration of catalyst can be avoided, a higher catalytic efficiency and a higher reaction rate are attained, the installation of re... | 10/10/1995 |
| 5447958 | Sulfamoyl-substituted phenethylamine derivatives, their preparation, and pharmaceutical compositions, containing them Pharmaceutical compositions are provided for the treatment of disorders in a subject, such as hypertension, congestive heart failure, angina pectoris, lower urinary tract dysfunction and prostatic hypertrophy. The compositions when administered to a subje... | 09/05/1995 |
| 5436368 | Intermediates in the preparation of 4,5-difluoroanthranillic acid Compounds of the formula ##STR1## which are intermediates in the preparation of 4,5-difluoroanthranilic acid, an intermediate itself in the synthesis of quinolone antibacterials, and methods of preparing these intermediates.... | 07/25/1995 |
| 5420346 | Preparation of adipic acid by hydrocarboxylation of pentenic acids Adipic acid is selectivity prepared by reacting water and carbon monoxide with at least one pentenic acid, in the presence of a catalytically effective amount of an iridium-based catalyst and at least one iodinated promoter therefor at an elevated tempera... | 05/30/1995 |
| 5420337 | Enzymatic reduction method for the preparation of compounds useful for preparing taxanes An enzymatic reduction method, particularly a stereoselective enzymatic reduction method, for the preparation of compounds useful as intermediates in the preparation of taxanes.... | 05/30/1995 |
| 5420332 | Diamine compounds A diamine compound having formula (I): ##STR1## wherein R1 is hydrogen, an alkyl group having 1 to 6 carbon atoms which may have a substituent, an alkoxyl group having 1 to 6 carbon atoms which may have a substituent, an aryl group which m... | 05/30/1995 |
| 5417958 | Heavy metal clusters for use as imaging agents The present invention relates to novel compounds for use as imaging agents. In particular, the present invention relates to imaging agents comprising a heavy metal cluster having 2 to 8 atoms of the same of different heavy metal elements, and at least one... | 05/23/1995 |
| 5416236 | Aniline derivatives and process for producing the same Disclosed herein is a process for producing a sulfoneamide represented by the following formula (6) as an intermediate of a 6-haloalkyl-3-phenyluracil derivative, from as a starting material 4-halogeno-3-nitroaniline (9) or 2-halogeno-5-nitroaniline (10):... | 05/16/1995 |
| 5411149 | Aqueous biphasic extraction process with pH and particle control A process for aqueous biphasic extraction of metallic oxides and the like from substances containing silica. Control of media pH enables efficient and effective partition of mixture components. The inventive method may be employed to remove excess silica ... | 05/02/1995 |
| 5412149 | Process for the preparation of 2-oximinoacetic acid derivatives A new process and new intermediates are described for the preparation of 2-oximinoactic acid derivatives of the formula (I) ##STR1## in which R1, R2, n, Z and Ar have the meaning given in the description and which are used as pe... | 05/02/1995 |
| 5405994 | Disodium 4-chlorophenylthiomethylenebisphosphonate monohydrate, its preparation and pharmaceutical compositions in which it is present The present invention relates to disodium 4-chlorophenylmethylenebisphosphonate monohydrate. The invention also relates to a method of preparing this form of the monohydrate, as well as to pharmaceutical compositions in which disodium tiludronate monohydr... | 04/11/1995 |
| 5405988 | 9-substituted bicyclo[3.3.0]octane derivatives, process for their production and their pharmaceutical use The invention relates to 9-substituted bicyclo[3.3.0]octane derivatives of formula I, ##STR1## and their salts with physiologically compatible bases, as well as the -, ଲ- or γ-cyclodextrin clathrates, as well as the compounds of fo... | 04/11/1995 |
| 5401852 | Process for the stereochemical inversion of (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R) enantiomers Intermediates for transforming (2S,3S)-2-amino-3-phenyl-1,3-propanediols into their (2R,3R)-enantiomers are described. The final compounds are useful intermediates for the synthesis of antibiotics like chloramphenicol, Thiamphenicol and Florfenicol.... | 03/28/1995 |
| 5399718 | Direct fluorination process for making perfluorinated organic substances A liquid phase process for making perfluorinated organic substances which comprises directly contacting in a temperature-controlled reactor a diluted solution or dispersion of a perfluorinateable, organic substance in a liquid, inert medium with a stoichi... | 03/21/1995 |
| 5393902 | Process for the preparation of bis(amidocarboxylic acids) A process is reported for the preparation of bis(amidocarboxylic acid) involving reacting an ester with an aminocarboxylate compound, the latter being formed from lactams or aminocarboxylic acids and salts thereof. The ester and aminocarboxylate compound ... | 02/28/1995 |
| 5393922 | Catalytic direct oxidation of hydrocarbons to acids A process for catalytic direct oxidation of hydrocarbons, particularly lower alkanes and single ring aromatics, to acids by dioxygen under mild temperature conditions using specified metal or metal salt catalysts. Turnovers in excess of 1000 for acetic ac... | 02/28/1995 |
| 5391822 | Process for the preparation of branched alkoxyalkanoic acids A process for the preparation of a branched alkoxyalkanoic acid by reacting the corresponding branched alkoxyalkanol with a stable free radical nitroxide in the presence of a NOX -generating compound at a temperature in the range of from about ... | 02/21/1995 |
| 5391815 | Method of separating vinylphosphonic acid from crude mixtures Method of separating vinylphosphonic acid from crude mixtures. The invention relates to a method for separating vinylphosphonic acid from crude mixtures, the separation being carried out by extraction with alcohols and/or ketones, which in each case comprise a... | 02/21/1995 |
| 5387709 | Substituted sulfonamides, process of preparation and medicines containing same The present invention concerns new substituted sulfonamides, and the physiologically acceptable salts possibly in the form of complexes, esters and amides thereof, represented by the formula: ##STR1##... | 02/07/1995 |
| 5387713 | Process for purification of carboxylic acids Carboxylic acids produced by carbonylation and having iodide and oxidisable impurities are purified by contacting with hydrogen peroxide and recovering the purified acid by distillation or evaporation. Preferably a strong acid such as sulphuric acid is us... | 02/07/1995 |
| 5386054 | Process for the purification of polyisocyanates, the polyisocyanates thus purified and use thereof A process for the purification of organic polyisocyanates by mixing of the polyisocyanate with from 0.001 to 1% by weight of compounds containing trimethylsilyl groups at temperatures of from 20° to 150° C. The resultant mixture of organic polyisocyanat... | 01/31/1995 |
| 5382679 | Process for the preparation of glutathione S-acyl derivatives, compounds obtained from said process and an intermediate useful for the preparation thereof A selective and high yield process for S-acylating glutathione, comprising the eaction between glutathione and an acyl chloride or a carboxylic anhydride in trifluoroacetic acid is described.... | 01/17/1995 |
| 5380914 | Fungicidal 2-methoximinocarboxylic esters Fungicidal new 2-methoximinocarboxylic esters of the general formula (I) ##STR1## in which Ar represents one of the radicals ##STR2## A represents one of the radicals ##STR3## where Y represents one of the radicals ##STR4## n rep... | 01/10/1995 |
| 5371278 | Synthesis of ioversol using a minimal excess of acetoxyacetylchloride The use of a minimal excess of acetoxyacetylchloride as a reagent in the synthesis of N,N'-bis(2,3-dihydroxypropyl)-5-N-(2-hydroxy-ethyl)glycolamido-2,4,6-triio doisophthalamide.... | 12/06/1994 |
| 5364965 | Analogs of desferrioxamine B and method for synthesis thereof The invention relates to novel analogs of desferrioxamine, homologs thereof and methods for their synthesis.... | 11/15/1994 |
| 5364884 | Arginine compounds as ocular hypotensive agents The invention relates to arginine and arginine-like compounds and to methods employing these compounds as ocular hypotensive agents. These compounds are effective when applied topically, may be used in low concentrations and are nontoxic. Additionally, th... | 11/15/1994 |
| 5364964 | Process for preparing 1,2,3,4-butanetetracarboxylic acid Butanetetracarboxylic acid with acceptably low levels of color-causing contaminants, suitable for permanent press agent use, is prepared in high conversion and yield from tetraalkyl butanetetracarboxylates by a series of steps including purification of pr... | 11/15/1994 |
| 5354899 | Production process of 1,4,5,8-naphthalene tetracarboxylic acid There is disclosed a mass production process of 1,4,5,8-naphthalene tetracarboxylic acid with high collection efficiency. In the presence of an alkaline metallic catalyst, 1,3-butadiene was added to the ethyl radicals of ethyl-p-xylene, and cyclized to ... | 10/11/1994 |
| 5352824 | Process for the preparation of alkoxyalkanoic acids A process for the preparation of an alkoxyalkanoic acid by reacting the corresponding alkoxyalkanol with a stable free radical nitroxide in the presence of a metal salt selected from the group consisting of a copper salt, an iron salt and mixtures thereof... | 10/04/1994 |
| 5349083 | Solutions of peracids A dilute solution of a lower aliphatic peracid such as peracetic acid, having an equilibrium composition, is produced by contacting hydrogen peroxide with a lower aliphatic acid each at initial high concentrations in an aqueous reaction mixture to rapidly... | 09/20/1994 |
| 5344972 | Process for producing acetic acid There is disclosed a process for producing acetic acid in which methyl formate is isomerized into acetic acid with a catalyst containing at least one of Pd, Ru and Ir, at least one compound of said metals or a mixture thereof, and a promoter of a halide c... | 09/06/1994 |
| 5336801 | Processes for the preparation of 2,2,3,3-tetrafluoropropionate salts and derivatives thereof This invention relates to chemical processes for preparing tetrafluoropropionate salts and selected derivatives thereof.... | 08/09/1994 |
| 5336794 | Dual phase adsorption and treatment of glyceride oils Impurities, which may include soaps, gums, phospholipids and pigments, can be removed from chemically or physically refined glyceride oils in a dual phase adsorption and treatment process. In the first phase, the oil is contacted with amorphous silica to ... | 08/09/1994 |
