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| Number | Title | Issue Date |
| 5120655 | Riboflavin producing strains of microorganisms Strains of yeast of the species Candida famata are disclosed which can produce 10 grams of riboflavin per liter in 6 days, and in particular, strains identified by ATCC Accession Nos. 20849 and 20850. Riboflavin yields of more than 20 grams per liter in 2... | 06/09/1992 |
| 5112750 | Immobilized cells and culture method utilizing the same Novel immobilized cells are prepared by immobilizing microbial cells in a gel carrier wherein an absorbent for organic solvents harmful to the cells is dispersed. A method for normally culturing these immobilized cells is utilized in a medium that contain... | 05/12/1992 |
| 5109133 | Antibiotic trienomycins and their production Novel compounds of the formula ##STR1## wherein R is hexahydrobenzoyl, isovaleryl or 2-methylbutyryl, and pharmaceutically acceptable salts thereof. The novel compounds designated as Trienomycins A, B and C are produced by culturing a microorganism ... | 04/28/1992 |
| 5106994 | Agents and method of production thereof This invention relates to new agents designated LL-F28249, LL-F28249ଲ, LL-F28249γ, LL-F28249δ, LLF28249&3xb5;, LL-F28249.zeta., LL-F28249η, LL-F28249θ, LL-F28249.iota., LL-F28249.kappa., LL-F28249λ, LL-F28249μ, LL-F28249.nu., and L... | 04/21/1992 |
| 5104800 | One-step cephalosporin C amidase enzyme A process for the one-step conversion of cephalosporin C and derivatives thereof to the corresponding 7-aminocephalosporanic acid and derivatives comprising treating said cephalosporin C and derivatives with a cephalosporin C amidase enzyme of a recited s... | 04/14/1992 |
| 5102793 | Stereospecific keto reduction of bicyclooctandione-carboxylic acid esters by microorganisms A microbiological process for sterospecific monoketo reduction of racemic 3-keto-bicyclic carbacyclin intermediates to the corresponding optically active 30 hydroxy compounds is provided.... | 04/07/1992 |
| 5098835 | Process for producing L-threonine by fermentation Microorganisms belonging to the genus Providencia the species rettgeri at least leucine for the growth thereof, produce L-threonine by fermentation in higher yield and with increased amount of L-threonine accumulated.... | 03/24/1992 |
| 5093243 | Process for the separation and recovery of nosiheptide Nosiheptide is recovered from a cultivation mixture obtained by cultivating a Nosiheptide-producing strain of Streptomyces by adding a water-miscible organic solvent, removing mycelia, precipitating Nosiheptide by adding water, which may be acidified, and... | 03/03/1992 |
| 5093250 | Process for producing optically active bicyclo[3.3.0]octanedione carboxylic acid esters Claimed is a process for the production of optically active bicyclo[3.3.0]octanedione-carboxylic acid esters of Formula I ##STR1## wherein R1 and R2 jointly represent an oxygen atom, or R1 and R2 individually re... | 03/03/1992 |
| 5093248 | BU-3862T antitumor antibiotic A new antitumor antibiotic designated herein as BU-3862T is produced by fermentation of Streptomyces hygroscopicus ATCC 53709. BU-3862T and its diacetyl and dihydro derivatives inhibit the growth of tumors in experimental animals.... | 03/03/1992 |
| 5087566 | Process for producing L-threonine Disclosed is a process for producicng L-threonine, which comprises culturing in a medium a microorganism belonging to the genus Escherichia and having a resistance to cysteine or cystine, or their analogue and an ability to produce L-threonine until L-thr... | 02/11/1992 |
| 5079162 | Reticulated cellulose and methods and microorganisms for the production thereof A method and media for producing bacterial cellulose under agitated culture conditions resulting in sustained production over an average of 70 hours of at least 0.1 g/liter per hour are achieved. A unique reticulated cellulose product is produced using th... | 01/07/1992 |
| 5077207 | Process for the production of L-threonine by fermentation A process for the production of L-threonine, comprising cultivating a mutant bacterial species belonging to the genus Brevibacterium from which dihydrodipicolinate synthase has been deleted or removed in a liquid medium; accumulating the L-threonine as a ... | 12/31/1991 |
| 5077202 | Process for producing a glycolipid having a high eicosapentaenoic acid content A process for producing a glycolipid having a high eicosapentaenoic acid (EPA) content is provided, which process comprises fractionating the whole lipids of marine chlorella by means of a combination of solvent-fractionation with column chromatography, w... | 12/31/1991 |
| 5075307 | Paraherquamide and dihydroparaherquamide as antihelminthic agents Paraherquamide and dihydroparaherquamide, known compounds, are disclosed as having antiparasitic activity. The compounds are fungal metabolites isolated from the known fungus Penicillium paraherquei, and from a newly isolated strain of Penicillium charles... | 12/24/1991 |
| 5073369 | Efomycins as performance promoters in animals The present invention relates to the use of microbiologically prepared compounds and their mixtures, which are called efomycins, as performance promoters in farm animals and processes for their preparation, and furthermore new efomycins and their mixtures... | 12/17/1991 |
| 5071976 | Novel heteropolysaccharide This invention provides a fermentation process which involves aerobically cultivating a strain of Methylophilus viscogenes under growth conditions to produce an accumulated quantity of a novel type of exopolysaccharide, such as heteropolysaccharide Poly 5... | 12/10/1991 |
| 5071751 | Process for preparing hyaluronic acid A process for producing a hyaluronic acid can be provided steadly, with a greatly improved productivity and at an inexpensive cost by incubating a hyaluronic acid-producing microbe in a culture medium formed by adding a blood serum or a bacteriolytic enzy... | 12/10/1991 |
| 5068187 | Process for producing D--amino acids The 5-substituted hydantoins represented below can be transformed into D--amino acids by the use of the cultured broth, cells or treated cells of the genus Hansenula: 5-substituted hydantoins: ##STR1## wherein R represents an alkyl, substitute... | 11/26/1991 |
| 5059532 | Microorganism belonging to genus Rhodococcus, and a process for producing alkene derivative and unsaturated fatty acid Disclosed herein is a process for producing an unsaturated fatty acid or derivative thereof which comprises culturing an unsaturated fatty acid-producing microorganism belonging to the genus Rhodococcus in a medium containing a saturated fatty acid or a d... | 10/22/1991 |
| 5049495 | Fermentation method for producing polyether antibiotics High titers of polyether antibiotics are obtained in a fermentation broth by inoculating a nutrient fermentation broth with a microorganism capable of producing a polyether antibiotic. Growth of the microorganism is established in the broth by incubating ... | 09/17/1991 |
| 5047339 | Recovery of polyether antibiotic material An aqueous medium having dispersed therein hydrophobic, polyether antibiotic-containing droplets, is mixed to cause the droplets to collide with each other and coalesce to form agglomerates which are separable from the medium.... | 09/10/1991 |
| 5047338 | Polyester Antibiotic preparation A polyether and antibiotic material is prepared by forming discrete polyether antibiotic-containing agglomerates which are separable from an aqueous medium, by producing a polyether antibiotic through cultivation of a polyether antibiotic-producing microo... | 09/10/1991 |
| 5041375 | Method of producing carnitine This invention relates to a method for producing carnitine comprising contacting, in a reaction medium, carnitinenitrile with (A) a nitrilase capable of hydrolyzing carnitinenitrile to form carnitine or (B) a microorganism containing said nitrilase.... | 08/20/1991 |
| 5041374 | Polyether antibiotic recovery and purification Polyether antibiotic material is liberated from agglomerates containing a lipid material and the polyether antibiotic material by separating the polyether antibiotic from the lipid through formation of an acid salt of the lipid and a desired acid salt of ... | 08/20/1991 |
| 5036004 | Process for producing L-serine A process for producing L-serine by the combination of chemical synthesis and enzyme chemical synthesis is disclosed. In this process L-serine is biochemically produced from 2-oxo-axazolidine-4-carboxylic acid or a salt thereof.... | 07/30/1991 |
| 5034321 | Method for the production of lipids containing bis-homo-γ-linolenic acid Method for the production of lipds containing bis-homo-γ-linolenic acid and/or arachidonic acid using microorganisms belonging to a genus Conidiobolus and capable of producing the lipids. The microorganisms are cultured on a medium containing an unsatura... | 07/23/1991 |
| 5034319 | Process for producing L-arginine Disclosed is a process for producing L-arginine, which comprises culturing in a medium a coryneform glutamic acid-producing bacterium having resistance to cysteine or a cysteine analogue and an ability to produce L-arginine, accumulating L-arginine in the... | 07/23/1991 |
| 5028537 | Novel antifungal substances and process for their production There is disclosed a series of macrolides isolated from the fermentation broth of a microorganism identified as MA-5000 which morphological analysis reveals to be a strain of Streptomyces hygroscopicus. The compounds' structures are present based upon ana... | 07/02/1991 |
| 5023184 | Antibiotics from myxococcus The invention relates to novel polycyclic alkaloids of formula ##STR1## in which R1 represents hydrogen or hydroxy, R2 represents hydrogen or acyl and A and B, independently of one another, each represents C.dbd.O or C--OH, and ... | 06/11/1991 |
| 5023175 | Novel production process of hyaluronic acid and bacterium strain therefor Hyaluronic acid can be produced efficiently and economically by culturing a strain belonging to a Streptococcus, which has hyaluronic acid producing ability, is hyaluronidase-nonproductive and shows anhemolytic property, and then collecting the hyaluronic... | 06/11/1991 |
| 5021343 | Method for producing trichothecenes Addition of L-leucine ot the fermentation medium of Fusarium mutant NRRL 18365 increases the production of the trichothecenes neosolaniol, 8-propionyl-neosolaniol, and 8-isobutyryl-neosolaniol. These materials are useful as toxins for the production of or... | 06/04/1991 |
| 5019503 | Method for production of l-threonine A method for producting L-threonine is described, comprising subjecting L- or DL-homoserine to enzymatic reaction in an aqueous medium in the presence of cells of biotin-requiring microorganisms belonging to the genus Brevibacterium and harvesting L-threo... | 05/28/1991 |
| 5017483 | Process for producing L-threonine A process is disclosed for producing L-threonine, the process involves culturing in a medium a microorganism of the genus Escherichia capable of producing L-threonine which has resistance to at least one of rifampicin, lysine, methionine, aspartic acid an... | 05/21/1991 |
| 5017484 | Process for preparing 3-chloro-1,2-propanediol A process for preparing an optically active 3-chloro-1, 2-propanediol by employing microorganism which can selectively metabolize (R)- or (S)-3-chloro-1,2-propanediol. The decomposition rate of the substrate can be accelerated and the substrate concentrat... | 05/21/1991 |
| 5015579 | Production of (-)trans-2,3-epoxysuccinic acid by fermentation A method for producing (-)trans-2, 3-epoxysuccinic acid, which can be used as a good starting material for the sythesis of optically active compounds such as optically specific single ଲ-lactam antibiotics, characterized in that filamentous fungi cap... | 05/14/1991 |
| 5013656 | Process for producing orotic acid by fermentation A process is disclosed for producing orotic acid, the process involves culturing in a medium a microorganism of the genus Corynebacterium which is capable of producing orotic acid and has resistance to a pyrimidine analogue or to both a pyrimidine analogu... | 05/07/1991 |
| 5008188 | Process for producing S-adenosyl-L-homocysteine Process for producing S-adenosyl-L-homocysteine, which comprises reacting adenosine with homocysteine by contacting them in an aqueous medium in the presence of cells or treated cells of a microorganism of a specified genus having the ability to synthesiz... | 04/16/1991 |
| 5008187 | Antifungal fermentation product A new antifungal agent which exhibits a moderately broad spectrum of activity towards filamentous fungi and also against Cryptococcus species of the yeast fungi, and which has been isolated from a solid stationary fermentation of an unidentified species o... | 04/16/1991 |
| 5004695 | Microbiological process for preparing 9-hydroxy-4-androstene-3,17-dione The invention relates to a process for the production of 9-hydroxy-4-androstene-3,17-dione from natural sterols of plant or animal origin or from mixtures thereof by the submerged aerobic fermentation of an enzyme-deficient, sterol-de-grading micro... | 04/02/1991 |
