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| Number | Title | Issue Date |
| 7270831 | Orally administrable opioid formulations having extended duration of effect Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for at least about 24 hours. A unit dose of the opioid analgesic contains ... | 09/18/2007 |
| 7132114 | Rapidly disintegrating methylcellulose tablets The present invention relates to a novel pharmaceutical composition and process for preparing swallowable methylcellulose tablets that disintegrate rapidly and meet USP disintegration standards in 0.1N hydrochloric acid as well as water. ... | 11/07/2006 |
| 7081246 | Stable hydroalcoholic compositions A hydroalcoholic lotion is disclosed which comprises (a) a lower alcohol and water in a weight ratio of about 35:65 to 100:0, and (b) between at least 0.5% and 8% by weight thickener system comprised of at least one emulsifier present in at least 0.05% by weight whe... | 07/25/2006 |
| 7070799 | Method for administering insulin to the buccal region A mixed micellar pharmaceutical formulation includes a micellar proteinic pharmaceutical agent, an alkali metal C8 to C22 alkyl sulfate, alkali metal salicylate, a pharmaceutically acceptable edetate and at least one absorption enhancing compounds. The absorption en... | 07/04/2006 |
| 7063864 | Morphine sulphate microgranules, method for preparing same and compositions containing same The present invention concerns a novel sustained-release oral formulation of morphine sulphate in the form of microgranules. Each microgranule comprises a neutral support grain coated with an active layer and with a sustained-release layer, characterized in that the... | 06/20/2006 |
| 7060295 | Formulations for the prevention and treatment of insulin resistance and type 2 diabetes mellitus The compositions and dosage forms of the invention are clinically useful as methods for increasing the effectiveness, efficiency and safety of biguanides (metformin) and/or sulfonylureas in the prevention and treatment of insulin resistance and diabetes mellitus, al... | 06/13/2006 |
| 7045146 | Templating of solid particles by polymer multilayers Process for encapsulation of an uncharged crystalline solid particle include treating the crystalline solid particle material with amphiphilic substances and subsequently coating the material with a layer of charged polyelectrolyte or coating the material with a mul... | 05/16/2006 |
| 7041316 | Stable oral pharmaceutical dosage forms The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such a dosage forms, and to a method of gastric acid pump inhibition and p... | 05/09/2006 |
| 7041319 | Fenofibrate pharmaceutical composition having high bioavailabilty The invention provides fenofibrate tablets comprising granulates, wherein the granulates can comprise carrier particles, micronized fenofibrate, and at least one hydrophilic polymer. ... | 05/09/2006 |
| 7037529 | Fenofibrate pharmaceutical composition having high bioavailability and method for preparing it The invention provides an immediate-release fenofibrate composition comprising (a) an inert hydrosoluble carrier covered with at least one layer containing fenofibrate in a micronized form having a size less than 20 μm, a hydrophilic polymer and, optionally, a surf... | 05/02/2006 |
| 7029700 | Micronized freeze-dried particles A process is provided for making dry, micronized particles of an agent, such as a drug. The method includes (a) dissolving a macromolecular material, preferably a polymer, in an effective amount of a solvent, to form a solution; (b) dissolving or dispersing the agen... | 04/18/2006 |
| 7029693 | Percutaneously absorptive preparation A percutaneously absorptive preparation is provided, which preparation having a support and an adhesive layer having a release-controlling layer, which is formed at least on one side of the support, wherein the adhesive layer contains an adhesive and 0.5–60 wt % o... | 04/18/2006 |
| 7025983 | Fast dissolving orally consumable films Physiologically acceptable films, including edible films, are disclosed. The films include a water soluble film-forming polymer such as pullulan. Edible films are disclosed that include pullulan and antimicrobially effective amounts of the essential oils thymol, met... | 04/11/2006 |
| 7022341 | Pharmaceutical compositions containing epinastine and pseudoephedrine The present invention relates to novel oral pharmaceutical compositions comprising as pharmaceutically active compounds a combination of an antihistaminic-effective amount of epinastine or a pharmaceutically acceptable salt thereof and of a decongestant-effective am... | 04/04/2006 |
| 7014846 | Phosphate-binding polymers for oral administration Phosphate-binding polymers are provided for removing phosphate from the gastrointestinal tract. The polymers are orally administered, and are useful for the treatment of hyperphosphatemia. ... | 03/21/2006 |
| 7014867 | Tablet comprising cetirizine and pseudoephedrine The present invention concerns a tablet comprising two distinct segments. More particularly, the invention relates to combinations of two pharmaceutical substances and methods of treatment of allergic disorders. ... | 03/21/2006 |
| 7008640 | Pharmaceutical composition for oral use with improved absorption The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by bringing said 3 components together and uniformly mixing at least th... | 03/07/2006 |
| 7008637 | Transdermally administered tolterodine as anti-muscarinic agent for the treatment of overactive bladder The present invention is drawn to set of formulations of at least one compound selected from tolterodine, salts thereof, prodrugs thereof and/or metabolites thereof, wherein in the set of formulations contains at least one device for transdermal administration and a... | 03/07/2006 |
| 7008639 | Fish gelatin compositions containing a hydrocolloid setting system The invention concerns Gelatin compositions for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed formulations like soft or hard gelatin capsules wherein the gelatin used ... | 03/07/2006 |
| 7008667 | Bioactive agent release coating A coating composition for use in coating implantable medical devices to improve their ability to release bioactive agents in vivo. The coating composition is particularly adapted for use with devices that undergo significant flexion and/or expansion in the course of... | 03/07/2006 |
| 7008641 | Osmotic device containing venlafaxine and an anti-psychotic agent The present invention provides an osmotic device containing controlled release venlafaxine in the core in combination with an anti-psychotic agent in a rapid release external coat. A wide range of anti-psychotic agents can be used in this device. Particular embodime... | 03/07/2006 |
| 7008644 | Method and apparatus for producing dry particles Method and apparatus for producing dry particles. Two liquid components are combined in a static mixer, atomized into droplets, and the droplets dried to form dry particles. Use of the static mixer enables incompatible liquid components to be rapidly and homogeneous... | 03/07/2006 |
| 7005138 | Method of systematically delivering SSRIs Methods and compositions are disclosed for the intravaginal or rectal delivery of selected serotonin reuptake inhibitors (SSRIs) to the systemic circulation. Such methods and compositions are useful in the treatment of depression, migraine headaches, chronic pain, p... | 02/28/2006 |
| 6998135 | Demineralized corticocancellous bone sheet A flexible, demineralized unitary bone sheet comprised of cortical cancellous bone having a residual calcium weight of 3.0% to 8.0% with a hyaluronic acid component having a molecular weight of 700,000 to 1,500,000 with the weight of the same ranging from 1% to abou... | 02/14/2006 |
| 6998134 | Biologically active implants This invention relates to an implant for treating pathological changes in the spinal column and/or locomotor system. According to one embodiment of the invention, the implant may be provided with an enamel-like or varnish-like coating up to 100 μm thick and made of... | 02/14/2006 |
| 6998140 | Dispersion comprising a non-ionic emulsifier The invention relates to a dispersion suitable for use as coating agent and binder for pharmaceutical forms, having a solids content of 10–70% by weight consisting of a) from 90 to 99% by weight of a methacrylate copolymer consisting of at least 90% b... | 02/14/2006 |
| 6989149 | Delivery of reactive agents via self emulsification for use in shelf-stable products Disclosed are treatment compositions comprising a liquid emulsifiable concentrate which comprises a chemically unstable reactive agent wherein the reactive agent is comprised of one or more reactive groups of the electrophilic, nucleophilic or protected thiol type, ... | 01/24/2006 |
| 6984399 | Solid pharmaceutical formulation containing lovastatin and simvastatin respectively, and its preparation The present invention relates to a novel solid pharmaceutical formulation containing lovastatin and simvastatin, respectively, with a particle size D(0.9) between 15 and 100 μm and a specific particle surface area between 1 and 4 m2/g, and to the process... | 01/10/2006 |
| 6984404 | Methods for preparing coated drug particles and pharmaceutical formulations thereof Disclosed are methods using pulsed laser ablation to prepare coated drug particles of uniform size and thickness. The coated drug particles ranged in size from several nanometers to several millimeters in diameter size, and were coated with organic polymer particle ... | 01/10/2006 |
| 6984401 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 01/10/2006 |
| 6974569 | Shampoos providing a superior combination anti-dandruff efficacy and condition Disclosed are shampoo compositions that provide a superior combination of anti-dandruff efficacy and conditioning, and a method of cleansing and conditioning the hair comprising applying to the hair and scalp an amount of said compositions. The anti-dandruff and con... | 12/13/2005 |
| 6972133 | Degradable animal chewing article possessing enhanced safety, durability and mouth-feel A chewable, biodegradable article for use as a pet toy comprises a matrix made of a natural polymer, a synthetic organic polymer or a mixture thereof, a natural or synthetic fibrous material that comprises fibers and that is bonded chemically or physically with the ... | 12/06/2005 |
| 6969526 | Paroxetine controlled release compositions A controlled release or delayed release formulation contains a selective serotonin reuptake inhibitor (SSRI) such as paroxtine. ... | 11/29/2005 |
| 6969529 | Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers The present invention is directed to nanoparticulate compositions comprising a poorly soluble drug and at least one copolymer of vinyl pyrrolidone and vinyl acetate as a surface stabilizer adsorbed to the surface of the drug. Also encompassed by the invention are ph... | 11/29/2005 |
| 6960348 | Goya derived cosmetic compositions for face and body A novel cosmetic preparation can be obtained by incorporating goya (momordica charantia) fruit and leaves into generic paraffin and cosmetic clay. The unique result can be used by estheticians in providing facial masks and cosmetic skin applications in beauty... | 11/01/2005 |
| 6960339 | Compositions structured with at least one polymer and methods of using the same A process for non-migrating deposit of a composition for making up at least one keratinous material, such as, for example, a lipstick or a foundation, comprising including in said a-composition for making up at least one keratinous material at least one liquid conti... | 11/01/2005 |
| 6949255 | Inhibitory chemical formulation with preservative system The present invention provides methods for preventing the transmission of HIV, methods for prophylaxis of HIV transmission and methods for reducing the risk of HIV transmission vaginally or rectally using compositions having at least one of polyquaternium, glycerin,... | 09/27/2005 |
| 6949259 | Solid preparations for oral use Solid preparations for oral use for facilitating the administration in a small dose of KRP-297, which is a ligand common to peroxisome proliferator-activated receptors PPAR α and PPAR γ (i.e., nuclear receptors) and has an effect of ameliorating insulin resistance... | 09/27/2005 |
| 6932982 | Encapsulated flavor and/or fragrance composition The invention relates to a granular delivery system based on a matrix combining at least a carbohydrate material with from 1 to 7% of prehydrated agar agar. The system disclosed is particularly stable in aqueous environments and is capable of providing the controlle... | 08/23/2005 |
| 6929803 | Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings A dosage form comprising a gelatin capsule formed with a composite wall and containing a liquid, active agent formulation where the wall comprises a barrier layer formed over the external surface of the gelatin capsule, an expandable layer formed over the barrier la... | 08/16/2005 |
