Did You Know...
...that it was melting ice cream that inspired the invention of the outboard motor? It was a lovely August day and Ole Evinrude was rowing his boat to his favorite island picnic spot. As he rowed, he watched his ice cream melt and wished he had a faster way to get to the island. At that moment the idea for the outboard motor was born!
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| Number | Title | Issue Date |
| 5532415 | R-enantiomer of N-propargyl-1-aminoindan, salts, compositions and uses thereof The subject invention provides R(+)-N-propargyl-1-aminoindan and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions containing same. The subject invention also provides methods of treating a subject afflicted with Parkinson'... | 07/02/1996 |
| 5514710 | Photocleavable derivatives of hydroxyprenesulfonic acids The invention describes the synthesis and use of photoactivated (or caged) fluorescent dyes. Upon illumination at less than about 400 nm the caged dyes release highly fluorescent, water soluble hydroxypyrenesulfonic acid dyes according to the following eq... | 05/07/1996 |
| 5514680 | Glycine receptor antagonists and the use thereof Methods of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma, hypoglycemia and surgery, as well as treating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease and D... | 05/07/1996 |
| 5503853 | Prophylactic and therapeutic applications of peroxidases Prophylactic and therapeutic applications of peroxidases for the manufacture of medicaments for the treatment and prevention and treatment of enveloped virus infections and, in particular, of herpes simplex and immunodeficiency virus infections. The medic... | 04/02/1996 |
| 5494934 | Guanidine compounds A compound of formula (I): ##STR1## in which: R1 represents substituted or unsubstituted phenyl or (C3 -C7) cycloalkyl, R2 represents trifluoromethyl or (C3 -C4) cycloalkyl, A represents --... | 02/27/1996 |
| 5491243 | Intermediate useful for the asymmetric synthesis of duloxetine This invention provides a stereospecific process for the synthesis of (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine, a key intermediate in the synthesis of duloxetine.... | 02/13/1996 |
| 5491263 | Aminoethylation process for production of substituted ethylene diamines A process is disclosed for producing a substituted ethylenediamine, the process comprising reacting an oxazolidinone with a secondary amine or an alkanolamine. The process includes, in one aspect, reacting precursors of the oxazolidinone in situ.... | 02/13/1996 |
| 5491264 | Preparation of isophorone diamine Isophorone diamine is prepared from isophorone nitrile by imination using a supported heteropoly acid catalyst to form the ketimine followed by the reduction of the ketimine to form the diamine.... | 02/13/1996 |
| 5491157 | Method and composition for the prevention, control and amelioration of soilborne fungi and disease caused thereby Methods and compositions utilizing 2-amino-5-thiazolyl thiocyanate compounds and their derivatives for the control of soilborne fungi and disease caused thereby are described.... | 02/13/1996 |
| 5489695 | Sulfonylureas N-Phenylsulfonyl-N'-pyrimidinyl-,-N'-triazinyl- and-N'-triazolylureas and -thioureas of formula I ##STR1## in which X is oxygen, sulfur, SO or SO2 ; W is oxygen or sulfur, R1 is hydrogen or methyl; R2 is hydrogen, flu... | 02/06/1996 |
| 5489708 | Synthesis of ioversol The reduction of the O-alkyl isomer content of 5-[N-(2-acetoxyethyl)acetoxyacetamido]-N,N'-bis(2,3-diacetoxypropyl)-2,4,6 -triiodoisophthalamide to thereby reduce and/or eliminate the production of impurities comparatively more difficult to remove during t... | 02/06/1996 |
| 5488167 | Synthesis of sphingosines Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from chiral arene diols using stereospecific reaction techniques to ... | 01/30/1996 |
| 5488049 | Method of treating learning and memory disorders using benzothiadiazide derivatives as nootropic agents The present invention is directed to the use of benzothiadiazide derivatives as nootropic agents to treat memory and learning disorders.... | 01/30/1996 |
| 5488166 | Synthesis of sphingosines Provided by the present invention is a process for the biocatalytic synthesis of optically pure sphingosines from achiral starting material. The stereoisomers of sphingosine are prepared from chiral arene diols using stereospecific reaction techniques to ... | 01/30/1996 |
| 5488165 | Process for the production of methyl amines A modified natural clinoptilolite, produced by treating a natural clinoptilolite with a suitable mineral acid or with a suitable alkali and then with a suitable mineral acid, is used as a catalyst in a process for the conversion of methanol and ammonia to... | 01/30/1996 |
| 5486510 | Method and compositions for modulating or control of immune responses in humans A mixture of ଲ-sitosterol glucoside and ଲ-sitosterol is administered to persons for the modulation or control of immune responses. The two compounds may be added in admixture or sequentially. Diseases such as viral and bacterial infections, au... | 01/23/1996 |
| 5482974 | Selected fungicides for the control of take-all disease of plants A compound for controlling Take-all disease of plants by applying, preferably to the seed prior to planting, a fungicide of the formula ##STR1## wherein R2 is ethyl, iso-propyl, propyl or allyl; A is N(CH3)1-n Hn... | 01/09/1996 |
| 5480858 | Cyclohexanedione derivatives Cyclohexanedione derivatives of the formula (I), ##STR1## wherein R1 is a C1 -C6 alkyl group, R2 is a C1 -C4 alkyl group, each of R3, R4 and R5 is inde... | 01/02/1996 |
| 5480902 | Thienylpyrrole fungicidal agents There are provided fungicidal thienyl- and furylpyrrole compounds of formula I ##STR1## Further provided are compositions and methods comprising those compounds for the protection of plants from fungal infestation and disease.... | 01/02/1996 |
| 5480585 | Stripping liquid compositions A photoresist stripping liquid composition comprising an alkanol amine compound, a sulfone compound or sulfoxide compound, and a hydroxy compound. The composition is excellent in its photoresist stripping performance, safety and working efficiency, and do... | 01/02/1996 |
| 5480908 | ଲ3 -adrenergic agents benzodioxole dicarboxylates and their use in pharmaceutical compositions The invention is antiobesity/antidiabetes beta-3 agonists of the formula: ##STR1## wherein Ar, X, R2, R3, Y and n are as defined in the specification.... | 01/02/1996 |
| 5478959 | Method for preparing 1,2-dithiins and precursors of 1,2-dithiins A method for preparing 1,4-(Z,Z)-disubstituted-1,4-disulfurated-1,3-butadienes is disclosed. The butadienes can be further elaborated to provide 3,6-unsymmetrically-substituted-1,2-dithiins. Also disclosed are butadienes prepared by the method of the... | 12/26/1995 |
| 5478837 | Use of quinacrine in preventing adhesion formation Compositions and methods for prevention of adhesion formation, whereby an effective amount of quinacrine as active agent is administered for a period of time sufficient to permit tissue repair. The active agent is preferably administered in conjunction wi... | 12/26/1995 |
| 5476969 | Highly reactive polyoxyalkylene-polyols containing tertiary amino groups in bonded form, their preparation, and their use for the preparation of polyisocyanate polyaddition products The invention relates to highly reactive polyoxyalkylene-polyols prepared by oxyalkylation of an initiator molecule containing, in bonded form, at least 2 reactive hydrogen atoms and at least one tertiary amino group bonded via a spacer bridge, which pref... | 12/19/1995 |
| 5475022 | Phenyl or heteroaryl and tetrahydronaphthyl substituted diene compounds having retinoid like biological activity Compounds of Formula 1 ##STR1## wherein m is 1-4; R1 --R4 independently are hydrogen, lower alkyl of 1 to 6 carbons, Cl, Br, or I; R5 is hydrogen, lower alkyl of 1 to 6 carbons, Cl, Br, I, lower alkoxy or lower thioal... | 12/12/1995 |
| 5475140 | Process for producing N,N-disubstituted p-phenylenediamine derivative sulfate 4-Amino-3-methyl-N-ethyl-N-(ଲ-hydroxyethyl)-aniline sulfate which is used particularly as a developer for color photography can be easily produced in high yield and high quality by nitrosating N-ethyl-N-(ଲ-hydroxyethyl)-m-toluidine by use of a... | 12/12/1995 |
| 5466470 | Co-micronized bicarbonate salt compositions This invention provides a co-micronized bicarbonate salt composition which is a blend of ingredients having a particle size between about 0.01-1.0 micron. The composition is produced by mill co-micronization of a crystalline bicarbonate ingredient and a c... | 11/14/1995 |
| 5464607 | 5,5'-/(1,3-propanediyl) bis-/imino(2-oxo-2,1-ethanediyl)acetylimino/bis(2,4,6-triiodo-1,3-benzen edicarboxylamides), and contrast media containing them R2, R2 ', R3, and R3 ', which are the same or different, are one of the groups of formula --CH2 CH2 OH, --CH2 CH(OH) CH2 OH --CH(CH2 OH)CH(OH)CH2 OH, ... | 11/07/1995 |
| 5464841 | Use of delta opioid receptor antagonists to treat immunoregulatory disorders A therapeutic method is provided to elevate a depressed mammalian autologous mixed lymphocyte response and to alleviate the diseases associated therewith by the administration of an effective amount of certain selective delta opioid receptor antagonists t... | 11/07/1995 |
| 5463102 | Process for the continuous production of aryl carbonates Organic carbonates containing at least one aromatic ester group can be obtained in a continuous manner from carbonates containing at least one aliphatic ester group and a phenolic compound in the presence of a transesterification catalyst known per se by ... | 10/31/1995 |
| 5462966 | Methods for the prevention and control of cellular damage resulting from coronary artery occlusion-reperfusion Methods for protecting warm-blooded animals against the formation of myocardial infarct through the administration of 2-phenyl-1,3-propanediol dicarbamate are disclosed.... | 10/31/1995 |
| 5460798 | System for determining the quantity and identity of material ingested by user The present invention provides a device and method for determining the quantity and identity of a substance ingested by a user. A detectable material such as barium sulfate is formed into a marker and mixed with a foreign substance such as pills, capsules... | 10/24/1995 |
| 5459073 | Method and composition for preserving antigens and process for utilizing cytological material produced by same A method and composition for fixing and stabilizing tissues, cells, and cell components such that the antigenic sites are preserved for a useful period of time. The fixative employs a formaldehyde donor that is non-toxic, non-flammable, and that stabilize... | 10/17/1995 |
| 5457133 | R-enantiomers of N-propargyl-aminoindan compounds, their preparation and pharmaceutical compositions containing them R(+)-N-propargyl-1-aminoindan, its preparation and use and pharmaceutical compositions containing it. The novel compound was found to be useful for the treatment of human patients for Parkinson's disease, memory disorders, dementia of the Alzheimer type (... | 10/10/1995 |
| 5457233 | Process for the preparation of amines A process for the preparation of amines of formula ##STR1## wherein the variables are defined as in the claims, which comprises reacting 1 molar equivalent of an amine of formula ##STR2## with 0.8 to 1.5 molar equivalents of an aldehyde of formu... | 10/10/1995 |
| 5455264 | RS-thioctic acid with novel morphology RS-thioctic acid with a novel morphology which is obtained by a recrystallization process.... | 10/03/1995 |
| 5451566 | Herbicidal pyrrolopyridine compounds Herbicidal 1-aryl pyrrolopyridine compounds of the formula: ##STR1## wherein at least one of Y, Z or J is N or N--O and the remainder of Y, Z or J is C--R.... | 09/19/1995 |
| 5449831 | Process of preparing 2-methyl-3-aminobenzotrifluoride 2-methyl-3-aminobenzo-trifluoride is prepared with high yields and high productivity by first halogenating o-trifluoromethylbenzalhalide, then secondly hydrogenating 2-trifluoromethyl-4-halogeno-benzalhalide formed by the first reaction, then thirdly nitr... | 09/12/1995 |
| 5449693 | Benzene derivatives, their preparation and pharmaceutical compositions in which they are present The present invention relates to compounds of the formula ##STR1## in which: R1 is hydrogen or a halogen atom; R2 is a cyclohexyl or a phenyl; R3 is a (C3 -C6) cycloalkyl; R4 is hydrogen, (C | 09/12/1995 |
| 5449826 | 5-amino-2-phenoxysulfonanilide compound To provide an excellent compound having anti-inflammatory, antipyretic, analgesic and antirheumatic actions. A 5-amino-2-phenoxysulfonanilide compound represented by the formula: ##STR1## and the salts thereof have potent anti-inflammatory, antipyretic, ... | 09/12/1995 |
