...that when IBM conducted a market study of Chester Carlson's invention in 1959, the company concluded that it would take only 5000 units of his new product to saturate the market? IBM therefore declined to be part of the new product introduction. Too bad for IBM. Carlson's invention was the xerography process, and his new product was the beginning of the Xerox Corporation. It is estimated that every day, worldwide, 3,000,000,000 copies are made!!
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| Number | Title | Issue Date |
| 7018612 | Method of preparing a radioactive rhenium complex solution The invention relates to a method of preparing a solution of a radioactive rhenium complex, by reacting at elevated temperature a radioactive perrhenate in a substantially aqueous solution with a ligand in the presence of a reductant and optionally an antioxidant un... | 03/28/2006 |
| 6762315 | Method for producing (1,1′,4, 11″)-terphenyl compounds The invention relates to a method for producing [1,1′:4′,1″]-terphenyl compounds of the formula which comprises reacting a metal aryl of the formula with a boric ester ... | 07/13/2004 |
| 6632958 | Process for producing a purified prostaglandin derivative An alkene (1) is added to cyclopentenone (2) under the action of an alkyl lithium and an organic copper reagent to form an adduct, said adduct is reacted with e.g. a carboxylic anhydride (4) to obtain a prostaglandin derivative (6), which is then treated ... | 10/14/2003 |
| 6602861 | Acylated phospholipid drugs This invention relates to a method for improving the efficiency of a drug containing a free carboxy group, the improvement comprising esterifying said carboxy group to the hydroxy group of the glycerol portion of a glycerolphospholipid ester having the fo... | 08/05/2003 |
| 6596670 | Use of selected oleophilic ethers in water-based drilling fluids of the O/W emulsion type and corresponding drilling fluids with improved ecological acceptability The use is disclosed of at least substantially water-insoluble ethers which are fluid and/or at least plastically deformable at working temperature and have flash points of at least 80° C., of mono- and/or polyfunctional alcohols of natural and/or synthe... | 07/22/2003 |
| 6552183 | Moncyclic L-nucleosides analogs Novel monocyclic L-Nucleoside compounds have the general formula ##STR1## Embodiments of these compounds are contemplated to be useful in treating a wide variety of diseases including infections, infestations, neoplasms, and autoimmune diseases. Viewed in... | 04/22/2003 |
| 6531626 | Method for producing cyclopropanecarboxylates There is disclosed a method for producing cyclopropanecarboxylates of the formula (3): ##STR1## by transesterification in the presence of a lanthanoid metal alkoxide... | 03/11/2003 |
| 6528640 | Synthetic ribonucleic acids with RNAse activity Novel nucleotide triphosphates, methods of synthesis and process of incorporating these nucleotide triphosphates into oligonucleotides, and isolation of novel nucleic acid catalysts (e.g., ribozymes) are disclosed. Also, described are the use of novel enz... | 03/04/2003 |
| 6506788 | N-linked urea or carbamate of heterocyclic thioesters for vision and memory disorders The present invention relates to pharmaceutical compositions comprising and methods of using an N-linked urea or carbamate of a heterocyclic thioester for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory perfor... | 01/14/2003 |
| 6495579 | Method for treating multiple sclerosis Methods and compositions for treating or preventing inflammatory diseases such as psoriasis or multiple sclerosis are provided, comprising the step of delivering to the site of inflammation an anti-microtubule agent, or analogue or derivative thereof.... | 12/17/2002 |
| 6492420 | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy The present invention relates to compounds being esters of 5-aminolevulinic acids or pharmaceutically acceptable salts thereof, including compounds of formula (I) R22 N--CH2 COCH2 --CH2 CO--OR1 ... | 12/10/2002 |
| 6492349 | Aminosugar and glycosaminoglycan composition for the treatment and repair of connective tissue A therapeutic composition for the protection, treatment and repair of connective tissue in mammals and a method for the treatment of connective tissue in mammals by the administration of the composition. The composition includes glucosamine and preferably... | 12/10/2002 |
| 6475991 | Use of -alkylglucosides and -alkylglucoside esters as anti-microbial an agents The present invention embraces methods and compositions which employ antimicrobial compositions which are -alkylglucosides and esters thereof.... | 11/05/2002 |
| 6472555 | Process for the production of esters from alcohols using acetic acid as acetylating and clays as catalysts The present invention relates to a process for the preparation of esters from alcohols using acetic acid as acetylating agent and clays as catalysts, which comprises the preparation of esters in a single step from the reaction of aliphatic, acyclic, cycli... | 10/29/2002 |
| 6465679 | Carbamate functional oligomers and coatings therefrom This invention involves a carbamate functional polymer or oligomer made by reacting a cyclic carbonate with ammonia or a primary amine, then reacting the resulting hydroxycarbamate with a polyfunctional material containing groups reactive with hydroxyl gr... | 10/15/2002 |
| 6465690 | Process for the preparation of polyamino succinic acids and derivatives thereof A process for preparing polyamino monosuccinic acids, salts or chelates thereof by (a) reacting a maleic or fumaric acid ester or mixtures thereof with a polyamino compound in a primary alcohol as a solvent, (b) hydrolyzing the product obtained in step (a... | 10/15/2002 |
| 6462232 | Production process for acrylic acid under controlled temperature conditions Provided is a process for producing acrylic acid stably at a high yield over a long period of time by subjecting acrolein or acrolein-containing gas to catalytic vapor phase oxidation. The above process is characterized by controlling the reaction so that... | 10/08/2002 |
| 6458991 | Preparation of (meth)acrylates Compounds having alcoholic hydroxyl groups are esterified with acrylic or methacrylic acid in the presence of copper(II) salts or mixtures thereof as polymerization inhibitors and in the presence of a hydrocarbon as a water-entraining agent with removal o... | 10/01/2002 |
| 6458996 | Process for the production of acetic acid In a process for the production of acetic acid by carbonylation of methanol and/or a reactive derivative in the presence of a Group VIII noble metal carbonylation catalyst, methyl iodide co-catalyst at a concentration of at least 2 wt %, optionally at lea... | 10/01/2002 |
| 6458987 | Citronellyl and/or dihydrocitronellyl lactates, their preparation and their use The invention concerns novel chemical compounds, namely citronellyl lactate and dihydrocitronellyl lactate and their optically active forms. The invention also concerns the method for obtaining them. The invention further concerns their use in the field o... | 10/01/2002 |
| 6458993 | Cyanate esters having flame resistant properties The present invention relates to novel aromatic cyanate ester compounds containing at least two rings linked by a group containing an unsaturated group. The present invention further relates to compositions and prepolymers of said novel aromatic cyanate e... | 10/01/2002 |
| 6455690 | L-8-oxo-7-propyl-7,8-dihydro-(9H)-guanosine Novel nucleosides having the structure of Formula 1 and Formula 2 are contemplated. In one aspect of the invention, controlled release dosage forms are particularly contemplated. Further, alternative routes of administration of the nucleosides having the ... | 09/24/2002 |
| 6452037 | Multioligonanilinated fullerenes A compound, of the following formula: ##STR1## Also disclosed is a pharmaceutical composition containing a pharmaceutically effective amount of the compound.... | 09/17/2002 |
| 6451531 | Dioxetane labeled probes and detection assays employing the same Probes labeled with 1,2-dioxetane precursors can be employed in a variety of assays. The probes may be nucleic acid, peptide nucleic acid, proteins including enzyme, antibody or antigen, steroid, carbohydrate, drug or non-drug hapten. The probe is provide... | 09/17/2002 |
| 6452043 | Carbonylation of lower alkyl alcohols and their derivatives using metals supported on carbonized polysulfonated divinylbenzene-styrene copolymers A method for producing esters, carboxylic acids and mixtures thereof includes contacting, under carbonylation conditions, lower alkyl alcohols, ethers, lower alkyl alcohol derivatives and mixtures thereof and carbon monoxide with a catalyst having a catal... | 09/17/2002 |
| 6447998 | 2-Aminopyridine and 2-pyridone C-nucleosides, oligonucleotides comprising, and tests using the same oligonucleotides The present invention provides 2-aminopyridine and 2-pyridone C-nucleosides and oligonucleotides containing the subject nucleosides. The nucleosides are useful in the preparation of the subject oligonucleotides. The oligonucleotides are useful in oligonuc... | 09/10/2002 |
| 6444652 | ଲ-L-2'-deoxy-nucleosides for the treatment of hepatitis B This invention is directed to a method for treating a host infected with hepatitis B comprising administering an effective amount of an anti-HBV biologically active 2'-deoxy-ଲ-L-erythro-pentofuranonucleoside or a pharmaceutically acceptable salt or ... | 09/03/2002 |
| 6441150 | Compounds for the Synthesis of Nucleotide or oligonucleotide phosphoramidites This invention presents novel methods for recovery of phosphoramidites from the waste products of oligonucleotide synthesis. The methods include reacting a tribromophenoxydichlorophosphorane with an H-phosphonate in the presence of an amine.... | 08/27/2002 |
| 6437160 | 3-heteroatom substituted and two carbon homologs of 15-HETE and methods of use 3-heteroatom substituted and two carbon homologs of 15-HETE, and their derivatives, compositions and methods of their use for treating dry eye are disclosed.... | 08/20/2002 |
| 6436994 | Heteroatom-interrupted analogs of 15-hydroxyeicosatetraenoic acid and methods of use Heteroatom-interrupted HETE derivatives and methods of their use for treating dry eye are disclosed.... | 08/20/2002 |
| 6433222 | Method for producing acrylic acid A process for the preparation of acrylic acid by: (a) preparation of a gaseous product mixture which essentially has the composition of a reaction mixture of catalytic gas-phase oxidation of C3 -alkanes, C3 -alkenes, C3 -alkano... | 08/13/2002 |
| 6429315 | Process for preparing N6-substituted adenosine derivatives This invention is directed to a process for preparing N6-substituted adenosine derivatives, to intermediates useful therefor and to methods of preparing these intermediates.... | 08/06/2002 |
| 6423727 | Certain thiol inhibitors of endothelin-converting enzyme Disclosed as endothelin converting enzyme inhibitors are the compounds of the formula ##STR1## wherein the variables have the meanings as defined hereinbefore.... | 07/23/2002 |
| 6423834 | KDO aldolase and condensation reactions employed therewith Aureobacterium barkerei strain KDO-37-2 (ATCC 49977) and KDO aldolase (EC 4.1.2.23) isolated therefrom are disclosed. The KDO aldolase is further disclosed to have a broad substrate specificity with respect to its reverse reaction, i.e. the condensation o... | 07/23/2002 |
| 6423694 | Method of treating otitis media with uridine triphosphates and related compounds A method of promoting drainage of congested middle ear fluid in a subject in need of such treatment is disclosed. The method comprises administering to the middle ear of the subject a uridine triphosphate such as uridine 5'-triphosphate (UTP), an analog o... | 07/23/2002 |
| 6420591 | Carbamates and compositions thereof, and methods for their use for treating cancer, inflammation, or a viral infection The present invention relates to novel carbamates and pharmaceutically acceptable salts thereof; compositions comprising the carbamate or a pharmaceutically acceptable salt thereof; and methods for treating cancer, inflammation, or a viral infection compr... | 07/16/2002 |
| 6420599 | Chemical process for the stereoselective synthesis of R-(-)-carnitine A process is described for the stereoselective synthesis of R-(-)-carnitine in which the characterizing step is condensation of glycerol with an amine of (-)camphorsulfonic acid.... | 07/16/2002 |
| 6420347 | Method of treating ciliary dyskinesia with uridine triphosphates and related compounds A method of stimulating ciliary beat frequency in a subject in need of such treatment is disclosed. The method comprises administering to the airways, ears, eyes, or genito-urinary tract of the subject a triphosphate nucleotide such as uridine 5'-triphosp... | 07/16/2002 |
| 6417389 | Process for the preparation of HPB esters This invention relates to a novel advantageous process for the stereoselective preparation of 2-hydroxy-4-phenylbutyrates (HPB esters) and of their precursors. This is done by starting from readily accessible -unsaturated -hydroxy-γ-keto es... | 07/09/2002 |
| 6417388 | Method for producing alkenyl-substituted bis(oxime ether) derivatives The process for preparing alkenyl-substituted bis(oxime ether) derivatives of the formula I ##STR1## where: R1 is unsubstituted C1 -C4 -alkyl or C2 -C4 -alkenyl-, C2 -C4 -alkynyl... | 07/09/2002 |