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| Number | Title | Issue Date |
| 8188118 | Method for treating multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione in combination with antibodies Methods of treating, preventing and/or managing cancer as well as and diseases and disorders associated with, or characterized by, undesired angiogenesis are disclosed. Specific methods encompass the administration of an immunomodulatory compound alone or in combina... | 05/29/2012 |
| 8178124 | Drug carrier and drug carrier kit for inhibiting fibrosis An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent; a drug delivery method with the use of the same; a drug containing the same; and a therapeutic method with the use of the drug. By binding a drug carrier ... | 05/15/2012 |
| 8173167 | Micelle composition of polymer and passenger drug Hydrophobic drugs become more practical for treatments by being encapsulated in micelle compositions for increasing solubility. Micelle compositions may include an excipient tocopherol and/or prodrug formulations of the drug. Micelles extend the time period the drug... | 05/08/2012 |
| 8173170 | Drug carrier and drug carrier kit for inhibiting fibrosis An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent; a drug delivery method with the use of the same; a drug containing the same; and a therapeutic method with the use of the drug. By binding a drug carrier ... | 05/08/2012 |
| 8168224 | Sodium alginate microsphere vascular embolus containing water-soluble drug and preparation and application thereof The present disclosure relates to a kind of sodium alginate microsphere vascular embolus that contains water-soluble drug and preparation and application thereof. The embolus preparation falls into dry microsphere type and wet one that are made of degradable materia... | 05/01/2012 |
| 8163271 | Oral hygiene products and method of using the same The present invention is directed towards a composition for highly efficient and quick plaque and tartar removal and inhibition including pure ascorbic acid crystals and/or granulars (vitamin C) and an enamel repairing composition such as hydroxyapatite. The composi... | 04/24/2012 |
| 8147813 | Detergent cosmetic compositions comprising three surfactants and at least one fatty ester, and use thereof The present disclosure relates to novel detergent and conditioning compositions comprising, in a cosmetically acceptable medium, at least one sulfate or sulfonate anionic surfactant; at least one carboxylic anionic surfactant chosen from polyoxyalkylenated (C6 | 04/03/2012 |
| 8147867 | Liposomes useful for drug delivery The present invention provides liposome compositions containing substituted ammonium and/or polyanion, and optionally with a desired therapeutic or imaging entity. The present invention also provide methods of making the liposome compositions provided by the present... | 04/03/2012 |
| 8142813 | Polymer latex compound A polymer latex composition has an acrylonitrile component, a polychloroprene component, and a natural latex component. When these components are blended together and formed into a film, the film exhibits a resistance to ozone that is greater than a resistance to oz... | 03/27/2012 |
| 8142768 | Cosmetic preparation The invention relates to a cosmetic preparation containing a crosslinked (meth) acrylic acid ester resin powder having a compression strength of 0.7 to 10 kgf/mm2. The invention also relates to a cosmetic preparation, for example, in the form of a cosmeti... | 03/27/2012 |
| 8128956 | Food product for hairball treatment A pet food product for hairball treatment that includes a shell component completely surrounding an inner component to form one dual textured pet food product, wherein the shell component is harder than the inner component. The shell component can include a mixture ... | 03/06/2012 |
| 8124113 | Hydrophilic coating An antimicrobial coating slurry includes about 15.5 wt % of a wetting agent, about 6.0 wt % of an insolubilizer, about 1.1 wt % of a biocide agent, and about 7.8 wt % of an inorganic material that includes lithium oxide and the balance water. The slurry is applied t... | 02/28/2012 |
| 8119619 | Pregnane steroids and their use in the treatment of CNS disorders Steroid compounds possessing a hydrogen donor in 3beta position, either in the form of a hydroxy- or a sulfate group, function as efficient blockers of the 3alpha-hydroxy-pregnan-steroid action and thus have utility as therapeutic substances for the prevention and/o... | 02/21/2012 |
| 8119111 | Topical administration carrier composition and therapeutic formulations comprising same A topical administration carrier composition including water, glycerin and polysorbate, suitable for use in formulations with active ingredient compositions containing active ingredients such as minoxidil that are susceptible to systemic penetration, and solvents th... | 02/21/2012 |
| 8110178 | Dental-plaque detection system and dental-plaque detection method A dental-plaque detection system and dental-plaque detection method which are excellent in the detection accuracy of dental plaques and also capable of improving the situation to stain sites other than dental plaques (such as interdental parts and gums) are provided... | 02/07/2012 |
| 8106099 | Combination of phenylcarboxamides with blockers of the IKr channel and their use for the treatment of atrial arrhythmias The invention relates to the combination of one or more IKr channel blockers and of one or more Kv1.5 blockers, in particular phenyl-carboxamides of the formula Ia or Ib or pharmaceutically tolerable salts thereo... | 01/31/2012 |
| 8105082 | Compositions for removing stains from dental surfaces and methods of making and using the same Stain-removing oral compositions, such as gum compositions are herein provided. The compositions include a chelating agent and a surfactant. The surfactant includes a fatty acid salt and at least one component selected from nonionic and anionic surfactants. The fatt... | 01/31/2012 |
| 8097650 | Method of treating a condition associated with phosphorylation of TASK-1 This invention provides methods and compositions for treating a condition associated with phosphorylation of TASK-1 in a subject comprising administering to the subject an amount of an agent effective to overcome the phosphorylation dependent loss of TASK-1 function... | 01/17/2012 |
| 8097608 | Methods for treatment of cardiovascular disorders and diseases Propargylamine, propargylamine derivatives including N-propargyl-1-aminoindan, enantiomers and analogs thereof, and pharmaceutically acceptable salts thereof, are useful for prevention or treatment of cardiovascular disorders, diseases and conditions. ... | 01/17/2012 |
| 8093380 | Compounds with the bicyclo[4.2.1]nonane system for the treatment of infections The disclosed invention is a bicyclo[4.2.1]nonane and its pharmaceutically acceptable salt or prodrug, and its composition and method of use to treat Flaviviridae (Hepacivirus, Flavivirus, and Pestivirus) infections in a host, including animals, and especially human... | 01/10/2012 |
| 8093290 | Coolant solutions and compositions comprising the same A solution consisting essentially of menthyl lactate and menthol carboxamide dissolved in a solvent, such as propylene glycol, which solvent is acceptable for food, oral care or cosmetic products and a method of preparing it. ... | 01/10/2012 |
| 8088404 | Biocompatible controlled release coatings for medical devices and related methods Biocompatible coatings for medical devices are disclosed. Specifically, polymer coatings designed to control the release of bioactive agents from medical devices in vivo are disclosed wherein the solubility parameters of polymers and drugs are closely matched to con... | 01/03/2012 |
| 8080586 | Self-emulsifying preparations The invention relates to new self-emulsifying preparations containing (a) 7 to 20% by weight stearyl oligoglycoside, (b) 7 to 20% by weight cetyl oligoglycoside, (c) 0.1 to 3% by weight myristyl oligoglycoside, (d)... | 12/20/2011 |
| 8080554 | Methods for using extracellular adenosine inhibitors and adenosine receptor inhibitors to enhance immune response and inflammation A method is provided herein to increase an immune response to an antigen. The method includes administering an agent that inhibits extracellular adenosine or inhibits adenosine receptors. Also disclosed are methods to increase the efficacy of a vaccine and to increa... | 12/20/2011 |
| 8075911 | Transparent transdermal nicotine delivery devices A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%. ... | 12/13/2011 |
| 8075875 | Teeth whitening composition and methods Disclosed herein are teeth whitening compositions generally including an oxidizing agent (e.g., a peroxide), and an activating agent that has an emission wavelength between about 400 nm and about 570 nm (e.g., Eosin B). Methods of employing these compositions to whi... | 12/13/2011 |
| 8071574 | Implant improving local bone formation A bone implant comprises an active agent on at least a portion thereof. The active agent is locally deliverable to bone proximate the implant in at least a two-phased release scheme. A first phase rapidly releases a first quantity of the active agent, and at least a... | 12/06/2011 |
| 8067031 | Compositions and systems for forming crosslinked biomaterials and associated methods of preparation and use Crosslinkable compositions are provided that readily crosslink in situ to provide crosslinked biomaterials. The composition contains at least two biocompatible, non-immunogenic components having reactive groups thereon, with the functional groups selected so as to e... | 11/29/2011 |
| 8067035 | Chlorite formulations, and methods of preparation and use thereof Described herein are chlorite formulations having a pH between about 7 and about 8.5, wherein the chlorite formulations are substantially free of deleterious non-chlorite components. Described herein are chlorite formulations, including pharmaceutical formulations, ... | 11/29/2011 |
| 8062661 | Methods and compositions for treating skin wounds Methods of debriding a skin wound are provided. Embodiments of the subject methods include contacting the skin wound with a hydrogel patch debridement composition to debride the wound. Also provided are systems and kits for use in practicing the subject methods.... | 11/22/2011 |
| 8057784 | Particulate flavoring composition The present invention relates to particulate compositions comprising controlled release particles wherein discrete elements of flavouring-containing fat are dispersed in a gelatine matrix, the particles containing; 0.1-40 wt %, preferably 5-30 wt % of flavouring; 10... | 11/15/2011 |
| 8053078 | Medical devices having soft, flexible lubricious coatings Soft, flexible highly lubricious coatings for polymeric IOL insertion cartridges that allow IOLs to be easily inserted through small bore cartridges suitable for use with small (less than 3 mm) incisions are provided. These lubricious coatings allow IOLs to be inser... | 11/08/2011 |
| 8048448 | Nanoshells for drug delivery Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided. ... | 11/01/2011 |
| 8044234 | Bioabsorbable surgical composition Compounds are provided which can form bioabsorbable compositions useful as adhesives or sealants for medical/surgical applications. In embodiments, suitable compositions may possess various functional groups, including groups derived from multifunctional compounds, ... | 10/25/2011 |
| 8030436 | Poly(ester-amide) elastomers and their use with implantable medical devices The present invention relates to implantable medical devices comprising poly(ester-amide) elastomers in coating layers on the device. ... | 10/04/2011 |
| 8022095 | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs The invention is directed to methods and compositions that can be used in the treatment of headaches. In particular, methods and compositions are described involving the combination of a long-acting NSAID and a 5-HT1B/1D agonist. ... | 09/20/2011 |
| 8008333 | Single dose aromatase inhibitor for treating infertility The use of an aromatase inhibitor (AI) in the preparation of a medicament for use in inducing ovulation in a female suffering from anovulatory infertility which comprises administering to said female a single dose of the at least one aromatase inhibitor. The use of ... | 08/30/2011 |
| 7999146 | Dressing and method of treatment for a wound A dressing and method for treating high-tension wounds. First and second layers of a 2-octyl cyanoacrylate 16 adhesive are applied to a short, high-tension wound, with the first and second layers covering the wound and extending to at least about 2.5 mm (0.09... | 08/16/2011 |
| 7994186 | Pharmaceutical compositions containing camptothecins A camptothecin-containing pharmaceutical composition which contains: (a) camptothecin or a derivative thereof, and (b) one or more compounds selected from among ascorbic acid or a salt thereof, sodium hydrogen sulfite, sodium sulfite, potassium pyrosulfite, sodium e... | 08/09/2011 |
| 7989452 | Stable hydrazalazine pharmaceutical compositions The present invention relates to stable and highly purified stable hydralazine hydrochloride compositions and stable hydralazine-containing pharmaceutical compositions. A sterile aqueous injectable pharmaceutical composition suitable for parenteral administration is... | 08/02/2011 |
