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Patent No. 5593111

Safety System For Remove a Rider From a Vehicle by Deploying a Parachute

Methods and apparatus for reducing the velocity of a rider in or on an open cockpit vehicle when the rider is thrown from the vehicle.

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Jones, Dwayne C.


Primary examiner statistics: 534 patents; average approval time: 1027 days
Assistant examiner statistics: 286 patents; average approval time: 783 days

Patents as Primary Examiner

1                      
NumberTitleIssue Date
RE39921Chemical compounds
The invention relates to piperazine derivatives, to processes for their preparation, to pharmaceutical compositions containing them, and to their medical use. The novel compounds are antagonists of tachykinins, including substance P and other neurokinins. ...
11/13/2007
7230014Pharmaceutical formulation comprising glycine as a stabilizer
The present invention provides pharmaceutical formulations suitable for intravenous injection comprising a lyophilized anti-ulcerative agent reconstituted in isotonic solutions suitable for intravenous administration, such as 5% dextrose or 0.9% sodium chloride. The...
06/12/2007
7160899Adenosine AA receptor antangonists combined with neurotrophic activity compounds in the treatment of Parkinson's disease
This invention relates to the use of the combined action of a compound with neurotrophic activity and an adenosine A2A receptor antagonist for the treatment of Parkinson's disease. ...
01/09/2007
7157452Substituted 4,9-dihydrocyclopenta{imn}phenanthridine-5-ones derivatives thereof and their uses
This invention relates to compounds, pharmaceutical compositions, and methods of using the disclosed compounds for inhibiting PARP. ...
01/02/2007
7148233Treatment of cardiovascular and related pathologies
Methods for treating cardiovascular and related diseases such as hypertrophy are described. The methods are directed to concurrently administering a compound such as pyridoxal-5′-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with a therape...
12/12/2006
7144892Treatment of cardiovascular and related pathologies
Methods for treating cardiovascular and related diseases such as myocardial infarction are described. The methods are directed to concurrently administering a compound such as pyridoxal-5′-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with...
12/05/2006
7138405Pharmaceutical combinations
Pharmaceutical combinations suitable for treating the lower urinary tract symptoms (LUTS) associated with benign prostatic hyperplasia (BPH) in men are described herein. The combinations contain an alpha-adrenoceptor antagonist and a muscarinic antagonist that may b...
11/21/2006
7132430Treatment of cardiovascular and related pathologies
Methods for treating cardiovascular and related diseases such as arrhythmia are described. The methods are directed to concurrently administering a compound such as pyridoxal-5′-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with a therapeu...
11/07/2006
7132451Inhibition of TNF-α-initiated neutrophil response
The impact of lipoxin A4 (LXA4) and aspirin-triggered-lipoxins (ATL) was investigated in tumor necrosis factor (TNFα)-initiated neutrophil (PMN) responses in vitro and in vivo using metabolically stable LX analogs. At concentrations as low as ...
11/07/2006
7125880Corticotropin releasing factor antagonists
Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 an...
10/24/2006
7125889Treating of cardiovascular and related pathologies
Methods for treating cardiovascular and related diseases such as blood clots are described. The methods are directed to concurrently administering a compound such as pyridoxal-5′-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with a therape...
10/24/2006
7125909Sterile parenteral nutrition compositions
Pharmaceutical compositions containing 2,6-diisopropylphenol (propofol) are described for use as anaesthetics. A method for their preparation is described, as their use in producing anaesthesia including induction and maintenance of general anaesthesia and se...
10/24/2006
7122566Metaxalone products, method of manufacture, and method of use
Disclosed herein is a method of using metaxalone. In one embodiment, the method comprises obtaining metaxalone from a container providing information that metaxalone affects the activity of a cytochrome p450 isozyme. In another embodiment, the method comprises infor...
10/17/2006
7122679Multicyclic compounds and the use thereof
The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for e...
10/17/2006
7115625Treatment of cardiovascular and related pathologies
Methods for treating cardiovascular and related diseases such congestive heart failure are described. The methods are directed to concurrently administering a compound such as pyridoxal-5′-phosphate, pyridoxamine, pyridoxal, or a 3-acylated pyridoxal analogue with...
10/03/2006
7115649Methods of treating skin disorders using thio-oxindole derivatives
The present invention provides methods of treating skin disorders includes delivering to a mammal a composition containing a compound of formula I, or tautomers thereof, in a regimen, wherein formula I is: and wh...
10/03/2006
7115626Treatment of cardiovascular and related pathologies
Methods for treating cardiovascular and related diseases such as ischemia, ischemia reperfusion injuries, and myocardial ischemia, are described. The methods are directed to concurrently administering a compound such as pyridoxal-5′-phosphate, pyridoxamine, pyrido...
10/03/2006
7115647Method of inhibiting neoplastic cells with indole derivatives
A method for inhibiting neoplastic cells and related conditions by exposing them to substituted indole derivatives. ...
10/03/2006
7112591Composition and method for humane euthanasia of animals
A novel euthanasia composition for animals, especially companion animals, utilizes a combination of sodium pentobarbital with dibucaine. The composition is easy to administer, fast-acting and relatively painless. A humane method for euthanasia involves administering...
09/26/2006
7109198Method for treating obesity
The present invention relates, in general, to obesity, and, in particular, to a method of treating obesity and minimizing metabolic risk factors associated therewith using, for example, zonisamide or other weight-loss promoting anticonvulsant either alone or in comb...
09/19/2006
7109329Neurologically active compounds and compounds with multiple activities
This invention provides pharmacologically active compounds having neurological and other bio-active capability. These active compounds comprise the derivatives of guanidino, aminoguanidino, 2-imadazolino, 2-hydrazinoimidazolino or 2-guanidinobenzimidazolino groups.
09/19/2006
7101916Exo-S-mecamylamine formulation and use in treatment
A pharmaceutical composition includes a therapeutically effective amount of exo-S-mecamylamine or a pharmaceutically acceptable salt thereof, substantially free of exo-R-mecamylamine in combination with a pharmaceutically acceptable carrier. Preferably the amount is...
09/05/2006
7098335Pyrazolopyrimidine compositions
Compounds, compositions and methods are provided which are useful in the treatment of diseases through the inhibition of sodium ion flux through voltage-dependent sodium channels. More particularly, the invention provides pyrazolopyrimidines, compositions and method...
08/29/2006
7098224Hydroxylansoprazole methods
Methods and compositions are disclosed utilizing hydroxylansoprazole for the treatment of ulcers in humans. Hydroxylansoprazole exhibits a lessened liability toward drug-drug interactions than lansoprazole and a more predictable dosing regimen than lansoprazole. Hyd...
08/29/2006
70983382,3,4,4a-tetrahydro-1H-pyrazino(1,2-a) quinoxalin-5(6H)one derivatives
This invention provides compounds of formula I, wherein R is hydrogen or alkyl of 1–6 carbon atoms; R′ is hydrogen, alkyl of 1–6 carbon atoms, acyl of 2â€...
08/29/2006
7087608Use of PDGF receptor tyrosine kinase inhibitors for the treatment of diabetic nephropathy
The present invention relates to the use of PDGF receptor tyrosine kinase inhibitors, especially of N-phenyl-2-pyrim-idine-amine derivatives of formula (I), in which the symbols and substituents have the meaning as defined herein in free form or in pharmaceutically ...
08/08/2006
7071206Agents for treating neurodegenerative disorders
Compounds and methods of using these compounds to treat neurodegenerative diseases, especially Alzheimer's disease, are provided. The compounds that are provided for the treatment of neurodegenerative diseases can be represented by a general formula (I):
07/04/2006
7071196Chemical compounds
The invention relates to piperazine derivatives, to processes for their preparation, to pharmaceutical compositions containing them, and to their medical use. The novel compounds are antagonists of tachykinins, including substance P and other neurokinins. ...
07/04/2006
7067664Corticotropin releasing factor antagonists
Corticotropin-releasing factor (CRF) antagonists having the formulae wherein the dashed lines, A, B, Y, Z, G, R3, R4, R5, R6, R16 an...
06/27/2006
7053072Methods for the administration of amifostine and related compounds
The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy in a manner that significantly reduces or decreases the adverse or undesirable side-effects of the compounds as compared wi...
05/30/2006
7049346Swollen hydrogel for sphincter augmentation
A physiologically acceptable composition comprises a plurality of physiologically acceptable hydrogel particles which have been swollen in a water solution containing a low molecular weight water soluble organic compound, the solution having the ability to swell the...
05/23/2006
7041661Use of thiazolobenzoheterocycles for treating multiple sclerosis
The invention relates to the use of compound of Formula I in treating patients for inflammatory or neuropathic pain as well as various symptoms of multiple sclerosis ...
05/09/2006
7041836Antibiotic compounds
The present invention relates to carbapenems and provides a compound of the formula (I): or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof wherein: R1
05/09/2006
7019032Agent for treating Parkinson's disease comprising astrocyte function-improving agent as active ingredient
An agent for preventing and/or treating Parkinson's disease or Parkinson's syndrome, comprising, as an active ingredient, an astrocyte function-improving agent is disclosed. The astrocyte function-improving agent is preferably a compound represented by formula (I), ...
03/28/2006
7015232Stabilization of quinapril using magnesium oxide
The present invention is directed to ACE inhibitor-containing compositions stabilized by the presence of magnesium oxide. Preferably, the ACE inhibitor, quinapril, is protected from certain forms of degradation when prepared in a pharmaceutical composition consistin...
03/21/2006
7015250Methods and pharmaceutical preparations for normalizing blood pressure with (-)-hydroxycitric acid
A method whereby the blood pressure metabolism in an individual showing evidence of dysregulation is improved when that person receives an appropriate oral administration of (−)-hydroxycitric acid. The potassium salt of (−)-hydroxycitric acid is a preferred form...
03/21/2006
6998400Pharmaceutically active morpholinol
Disclosed is the compound (+)-(2S,3S)-2-(3-chlorophenyl)-3,5,5-trimethyl-2-morpholinol and pharmaceutically acceptable salts and solvates thereof, pharmaceutical compositions comprising them, and processes for their preparation; also disclosed is a method of treatin...
02/14/2006
6995165Methods, compositions, and kits for organ protection during systemic anticancer therapy
Methods, compositions, and kits are presented for local tissue protection during systemic administration of anticancer therapeutic agents. ...
02/07/2006
6987121Compositions and methods for hepatoprotection and treatment of cholestasis
Methods for the treatment of cholestatic liver disease and reduction and prevention of hepatic injury resulting from cholestasis via administration of a FXR ligand are provided. ...
01/17/2006
6984656Core modified porphyrins
The present invention is directed to novel photosensitive compounds that can be replicated with great certainty and provide applications for photodynamic therapy. ...
01/10/2006
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