Bizarre Patents
Decorative Jeweled Wheel Cover
An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.
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| Number | Title | Issue Date |
| 6372778 | Sulfonamide inhibitors of aspartyl protease The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical ... | 04/16/2002 |
| 6297269 | Substituted n-(indole-2-carbonyl-) amides and derivatives as glycogen phosphorylase inhibitors Compounds of the formula I: ##STR1## and their compositions are useful as glycogen phosphorylase inhibitors.... | 10/02/2001 |
| 6258815 | Specific immunophilin ligands as antiasthmatics and immunosuppressants The novel specific immunophilin ligands of the general formula I have an antiasthmatic and immunosuppressive action and are suitable for the preparation of drugs. ##STR1##... | 07/10/2001 |
| 6153662 | Aromatic maleimides and methods of using the same Aromatic maleimides and methods using the same are disclosed. Polymerization of compositions which include the compounds of the invention may be activated by irradiating the composition with radiation.... | 11/28/2000 |
| 6147208 | Process for simultaneously preparing caprolactam and hexamethylene diamine Caprolactam and hexamethylenediamine are prepared simultaneously starting from adiponitrile.... | 11/14/2000 |
| 6133308 | Synthesis of clasto-lactacystin beta-lactone and analogs thereof The present invention is directed to an improved synthesis of clasto-lactacystin-ଲ-lactone, and analogs thereof, that proceeds in fewer steps and in much greater overall yield than syntheses described in the prior art. The synthetic pathway relies u... | 10/17/2000 |
| 6130338 | Method of producing pyrrolidine derivatives A method for producing pyrrolidine derivatives such as 3,4-epoxypyrrolodines, 3-pyrrolidols and the like, by oxidizing 3-pyrrolines with at least one peroxide in the presence of at least one acid is disclosed. The 3-pyrrolines are produced by deriving cis... | 10/10/2000 |
| 6124465 | Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments Novel products of formula (I), their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments. ##STR1## In the formula (I), the following substituents are among the preferred: Ar represents ... | 09/26/2000 |
| 6124473 | Process for preparing (s)- and (R)--ethyl-2-oxo-1-pyrrolidineacetamide The present invention relates to a process for preparing (S)- and (R)--ethyl-2-oxo-1-pyrrolidineacetamide and (R)--ethyl-2-oxo-1-pyrrolidineacetamide. According to this process, the enantiomeric resolution of the racemic mixture of �... | 09/26/2000 |
| 6121479 | Isoxazole and crotonamide derivatives and their use as pharmaceuticals and diagnostics A compound of the formula ##STR1## where R1 is the radical of the formula II or III ##STR2## is suitable for the production of a pharmaceutical for the treatment of inflammations, carcinomatous diseases, or autoimmune diseases. A comp... | 09/19/2000 |
| 6118001 | Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity Disclosed are hydroxamic and carboxylic acid derivatives which are useful inhibitors of matrix metalloproteinase and/or TNF-mediated diseases, including degenerative diseases and certain cancers.... | 09/12/2000 |
| 6117822 | Substituted phthalimidocinnamic acid derivatives and intermediates for their preparation Substituted phthalimidocinnamic acid derivatives I ##STR1## where R1 is H or C1 -C4 -alkyl; R2 is H or halogen; R3 is CN, NO2, halogen, C1 -C6 -alkyl, C1 -C... | 09/12/2000 |
| 6114375 | Substituted cyclopropyl phenoxymethyl phenyl carbamates and their use as fungicides Compounds with fungicidal properties are presented having the formula ##STR1## wherein m and n are 0 or 1; X is hydrogen, halo, (C1 -C4)alkyl or alkoxy; Z is (C1 -C12) alkyl or haloalkyl; R, R1, ... | 09/05/2000 |
| 6114528 | Fluorinated amide compounds The invention is directed at novel fluorinated amide compounds of formula (1): ##STR1## wherein Rf is a divalent perfluoroalkylene or perfluoropolyether group, X is a group of formula (2), (3) or (4), and m is an integer inclusive of 0. ##STR2##... | 09/05/2000 |
| 6114371 | 3-(cyclohexanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors The present invention relates to novel 3-(cyclohexano-heteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be usefu... | 09/05/2000 |
| 6114542 | Ethers of polyalkyl or polyalkenyl N-hydroxyalkyl succinimides and fuel compositions containing the same Ethers of polyalkyl or polyalkenyl N-hydroxyalkyl succinimides having the formula: ##STR1## or a fuel soluble salt thereof. The compounds of formula I are useful as fuel additives for the prevention and control of engine deposits.... | 09/05/2000 |
| 6114541 | Method for the preparation of -Bromo-Lactam derivatives The invention is concerned with a new process for the preparation of compounds of formula ##STR1## wherein R is hydrogen, lower alkyl, lower alkoxy, cycloalkyl, cycloalkenyl, cycloalkyl-lower alkyl, lower alkenyl, lower alkynyl, aryl, aryl-lower... | 09/05/2000 |
| 6107491 | Polymerizable diketopyrrolopyrroles Diketopyrrolopyrroles of formula I ##STR1## wherein R1 is a radical of formula II --Y--X--Z--Q (II), wherein Y is --CR3 R4, --SO2 --, --CO--, --Si(Hal)2 --, ... | 08/22/2000 |
| 6107519 | Process to produce oxazolidinones The present invention includes a number of novel intermediates such as the (S)-secondary alcohol of formula (VIIIA) X2 --CH2 --C*H(OH)--CH2 --NH--CO--RN (VIIIA) and processes for production of pharmacologically useful o... | 08/22/2000 |
| 6100275 | 8-azabicyclo[3.2.1.]oct-2-ene derivatives, their preparation and use A compound having the formula, ##STR1## or any of its enantiomers or any mixture thereof, or a pharmaceutically acceptable salt thereof; wherein R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl or 2-hydroxyethyl; and R4 ... | 08/08/2000 |
| 6096778 | -ketoamide multicatalytic protease inhibitors This invention relates to -ketoamide inhibitors of multicatalytic protease (MCP), to compositions including such inhibitors, and to methods for the use of MCP inhibitors. The MCP inhibitors of the present invention are useful, for example, to retar... | 08/01/2000 |
| 6090841 | Substituted pyrrole derivatives as cell adhesion inhibitors Substituted pyrrole derivatives of Formula I are antagonists of VLA-4 and/or 댔 댧, and as such are useful in the inhibition or prevention of cell adhesion and cell-adhesion mediated pathologies. These compounds may be fo... | 07/18/2000 |
| 6090896 | Surfactant-assisted soil remediation A surfactant which is the reaction product of a hydrocarbyl-substituted succinic anhydride or a reactive equivalent thereof with at least one water-dispersible amine-terminated poly(oxyalkylene), is effective for use in soil remediation.... | 07/18/2000 |
| 6083936 | Boron heterocycle steroid mimics and associated pharmaceutical compositions and methods of use Boron heterocycle steroid mimics are provided that are useful as pharmaceutical agents, particularly in the treatment of estrogen-dependent disorders such as estrogen-dependent cancers. The compounds are also useful in diagnostic techniques such as magnet... | 07/04/2000 |
| 6080857 | Method of preparation of ଲ-amino acids A method for the preparation of ଲ-amino acid compounds is provided. The method includes contacting an amine nucleophile with an ,ଲ-unsaturated amide compound in the presence of a chiral Lewis acid complex. The chiral Lewis acid complex ... | 06/27/2000 |
| 6071943 | Imidazole derivative and medicine comprising the same as active ingredient Disclosed herein are an imidazole derivative represented by the following general formula (1): ##STR1## wherein R1 is a hydrogen atom, or an alkyl, alkoxy or alkoxycarbonyl group, and R2, R3 and R4 are the ... | 06/06/2000 |
| 6069156 | Indole derivatives as cGMP-PDE inhibitors Compounds of the formula (I): ##STR1## and their pharmaceutically acceptable compositions are useful in inhibiting the activity of cyclic guanosine 3',5'-monophosphate phosphodiesterase.... | 05/30/2000 |
| 6066741 | Process for the preparation of etodolac Process for the preparation of etodolac, comprising the following steps: a) reacting 7-ethyl-tryptophol of formula (II) with methyl 3-oxo-pentanoate of formula (III) thereby obtaining methyl 1,8-diethyl-1,3,4,9-tetrahydropyrano [3,4-bis] indole-1-acetate of fo... | 05/23/2000 |
| 6066666 | Anticonvulsant and anxiolytic lactam and thiolactam derivatives This invention relates to lactam and thiolactam derivatives having useful anticonvulsant and anxiolytic activity, pharmaceutical compositions containing these compounds and therapeutic applications using such compositions.... | 05/23/2000 |
| 6066648 | Integrin receptor antagonists The present invention relates to compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. More particularly, the compounds of the present invention are antagonists of the vitronectin receptors .nu. ... | 05/23/2000 |
| 6066663 | Oxidation derivatives of indolylalkylamines and their use as drugs The invention relates to derivatives of general formula I ##STR1## The invention also relates to pharmaceutical and cosmetic compositions comprising derivatives of general formula I.... | 05/23/2000 |
| 6066731 | Aminomethylation of tocopherols A process for the production of a Mannich reagent comprises reacting formaldehyde, especially paraformaldehyde, with a secondary amine in the complete or almost complete absence of a solvent. An alternative comprises reacting a diaminomethane produced fro... | 05/23/2000 |
| 6057357 | Peripherally selective kappa opioid agonists The compounds of the instant invention as those of Formula I ##STR1## or a pharmaceutically acceptable salt thereof are peripherally selective kappa opioid agonists that are useful in treating pain, inflammation, psoriasis and irritable bowel syndrom... | 05/02/2000 |
| 6057336 | Lactam metalloprotease inhibitors The present application describes novel lactams and derivatives thereof of formula I: ##STR1## or pharmaceutically acceptable salt forms thereof, wherein rings ring B is a 4-8 membered cyclic amide containing from 0-3 additional heteroatoms sele... | 05/02/2000 |
| 6054412 | Substituted 4,5-di(trifluoromethyl)pyrazoles and their use as herbicides and for desiccating/defoliating plants Substituted 4,5-di(trifluoromethyl)pyrazoles I ##STR1## and salts thereof, Use: as herbicides; for the desiccation/defoliation of plants.... | 04/25/2000 |
| 6054597 | Processes and intermediates for the preparation of cyclic urea HIV protease inhibitors This invention relates to novel compounds and derivatives thereof containing a trioxepane protected diol in addition to a hydrazone, hydrazine, amine, or cyclic urea moiety; methods for the preparation of said compounds; and the use of said compounds in p... | 04/25/2000 |
| 6054587 | Indole and azaindole inhibitors of fructose-1,6-bisphosphatase Novel indole and azaindole compounds of the following structure and their use as fructose-1,6-bisphosphatase inhibitors is described: ##STR1## and pharmaceutically acceptable prodrugs and salts thereof.... | 04/25/2000 |
| 6048979 | Preparation of N-arylmethyl aziridine derivatives, 1,4,7,10-tetraazacyclododecane derivatives obtained therefrom and N-arylmethyl-ethanol-amine sulphonate esters as intermediates Aziridines may be subjected to a cyclooligomerization reaction to produce polyazacycloalkane compounds useful for example in the preparation of chelating agents for use in diagnostic imaging contrast agents. N-benzyl-aziridine in particular is useful as i... | 04/11/2000 |
| 6046328 | Combination preparation, containing cyclosporin A or FK506 or rapamycin and a xanthine derivative Xanthines of the formula I ##STR1## are useful in producing a superadditive increase in immunosuppressive action when combined with immunosuppressive compounds such as CysA or FK506.... | 04/04/2000 |
| 6046229 | Polyaryl antitumor agents A compound of the formula: Ar1 --B--Ar2 wherein Ar1 is unsubstituted or substituted phenyl, thienyl, furanyl, or pyrrolyl, in which each substituent of the substituted phenyl, substituted thienyl, substituted furanyl, and subst... | 04/04/2000 |
