Class 800/19 - Bird (e.g., chicken, etc.)

Subclass of Class 800 - Multicellular living organisms and unmodified parts thereof and related processes
Definition: Subject matter wherein the transgenic nonhuman animal
No. of patents: 37
Last issue date: 08/09/2011

Number	Title	Issue Date
7994388	Depletion of endogenous primordial germ cells in avian species Methods for modulating primordial germ cell (PGC) numbers and/or development in avians are provided. In one embodiment, the presently disclosed subject matter provides a method for modulating primordial germ cells numbers in an avian embryo comprising immunizing a f...	08/09/2011
7795496	In vivo transfection in avians The present invention provides for methods of producing transgenic avians which may include delivering a heterologous nucleic acid to oviduct tissue of an avian wherein the nucleic acid enters a cell of the oviduct tissue and is expressed. ...	09/14/2010
7541512	Avians containing a lysozyme promoter transgene The invention provides for transgenic avians containing nucleic acids which include an exogenous lysozyme gene expression controlling nucleotide sequence which typically is linked to a polynucleotide encoding a heterologous polypeptide. ...	06/02/2009
7534929	Avians expressing heterologous protein This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of avians in order to express the exogenous sequences to alter the phenotype of the avians or to produce desired proteins. In particular, tran...	05/19/2009
7521591	Transgenic chickens that lay eggs containing exogenous proteins This invention provides eggs which contain exogenous proteins. The invention further provides transgenic chickens which express exogenous sequences in their oviducts, and vectors and methods for the stable introduction of exogenous nucleic acid sequences into the ge...	04/21/2009
7507873	Transgenic avians containing recombinant ovomucoid promoters Transgenic avians having a recombinant ovomucoid gene expression controlling region operably linked to one or more useful amino acid coding sequences. ...	03/24/2009
7476776	Method for improving germline transmission efficiency of avian primordial germ cells The present invention relates to a method for improving the germline transmission efficiency of avian primordial germ cells (PGCs), and methods for producing avian chimeras and transgenic using it. The present method comprises the steps of (a) isolating primordial g...	01/13/2009
7423194	Animal models for demyelination disorders This invention is in the field of neurology. Specifically, the invention relates to the discovery and characterization of molecular components that play a role in neuronal demyelination or remyelination. In addition, the invention relates to the generation of an ani...	09/09/2008
7381712	In vivo transfection in avians The present invention provides for methods of producing transgenic avians which may include delivering a heterologous nucleic acid to oviduct tissue of an avian wherein the nucleic acid enters a cell of the oviduct tissue and is expressed. ...	06/03/2008
7375258	Transgenic avians with an ovomucoid gene expression control region linked to a nucleotide sequence encoding a heterologous polypeptide The present invention provides novel isolated nucleic acids that comprise an avian nucleic acid sequence comprising a ovomucoid gene expression control region. The ovomucoid promoter region of the present invention will allow expression of an operably linked heterol...	05/20/2008
7355092	Genetic vaccines for the production of chicken egg-yolk antibodies against enterotoxigenic and other pathogens Genetic vaccine which comprises plasmid(s) containing genes coding for antigens of enterotoxigenic Escherichia coli (ETEC) strains is disclosed. Additionally, plasmids may consist of multiple copies of the same antigen (i.e. K88 or K99 fimbrial antigen) or mu...	04/08/2008
7351582	Cell lines The present invention relates to cells that can be passaged in culture and can be used for, among other things, promoter assays and the production of heterologous proteins. ...	04/01/2008
7339090	Microinjection devices and methods of use The present invention provides for microinjection devices comprising a needle and a viewing instrument wherein the viewing instrument provides magnified viewing of an object to an operator from an angle other than a right angle to the object. ...	03/04/2008
7335761	Avian gene expression controlling regions The present invention includes avian ovomucoid gene expression controlling regions which may be operably linked to one or more useful amino acid coding sequences. ...	02/26/2008
7323619	Method for producing transgenic birds and fish The present invention relates to methods for producing transgenic animals, particularly transgenic birds and fish, using retroviral constructs engineered to carry the transgene(s) of interest. ...	01/29/2008
7323618	Tissue specific expression of exogenous proteins in transgenic chickens Transgenes encoding exogenous proteins are stably integrated into embryonic stem cells and are present in the somatic tissue of transgenic or chimeric birds. The transgenes encode exogenous proteins and are expressed in any of endodermal, ectodermal, mesodermal, or ...	01/29/2008
7312374	Production of a transgenic avian by cytoplasmic injection This invention provides methods for the stable introduction of heterologous coding sequences into the genome of a bird and expressing the coding sequences to produce desired proteins or to alter the phenotype of the bird. The present invention provides preferred met...	12/25/2007
7294507	Ovomucoid promoters and methods of use The present invention includes nucleic acid molecules comprising an artificial chromosome and an avian ovomucoid gene expression controlling region operably linked to the coding sequence of a useful polypeptide. ...	11/13/2007
7259291	Enucleation of avian eggs by gamma irradiation A method of enucleating an egg by exposing the egg to gamma irradiation. The dose of gamma irradiation used is sufficiently high to halt development of the egg or embryo derived therefrom directed by the nucleus of the irradiated egg, but sufficiently low to enable ...	08/21/2007
7237505	Ovo activation of an egg in the shell The present invention relates to the field of avian reproduction. In particular, the present invention provides a method of activating an egg in a shell. The invention also provides a method of activating an egg in a shell, whereby a live chick is hatched. ...	07/03/2007
7199279	Recombinant promoters in avian cells The invention provides for cells containing nucleic acids which include lysozyme gene expression controlling region nucleotide sequences which typically are linked to a polynucleotide encoding a heterologous polypeptide. ...	04/03/2007
7176300	Avian lysozyme promoter The invention provides for lysozyme gene expression control regions which may include a 5′ matrix attachment region; an intrinsically curved region of DNA; a transcription enhancer; a negative regulatory element; at least one hormone responsive element; an avian C...	02/13/2007
7145057	Chimeric bird from embryonic stem cells Sustained cultures of avian embryonic stem cells are provided. Injection of avian embryonic stem cells into recipient embryos yields chimeras with a significant contribution from the embryonic stem cell phenotype. Transgene encoding exogenous proteins are stably int...	12/05/2006
7129390	Poultry Derived Glycosylated Interferon Alpha 2b This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of avians in order to express the exogenous sequences to alter the phenotype of the avians or to produce desired proteins. In particular, tran...	10/31/2006
7129062	Matrix attachment regions and methods for use thereof The present invention relates to compositions and methods for transfecting eukaryotic cells with nucleic acid vectors. In particular, the invention relates to the uses of Matrix Attachment Region (MAR) elements to increase stable and transient transfection efficienc...	10/31/2006
7041870	Transgenic transchromosomal rodents for making human antibodies The present invention provides novel transgenic nonhuman mammals capable of producing human sequence antibodies, as well as methods of producing and using these antibodies. ...	05/09/2006
6861572	Production of proteins in eggs Methods for preparing recombinant proteins, such as antibodies, in eggs are described. The method offers advantages over existing systems for preparing recombinant proteins including high yield, low cost and compatibility with animal protection regulations. In addit...	03/01/2005
6825396	Methods for tissue specific synthesis of protein in eggs of transgenic hens Vectors and methods are provided for introducing genetic material into cells of a chicken or other avian species. More particularly, vectors and methods are provided for transferring a transgene to an embryonic chicken cell, so as to create a transgenic hen wherein ...	11/30/2004
6730822	Vectors in avian transgenesis This invention provides vectors and methods for the stable introduction of exogenous nucleic acid sequences into the genome of a bird and for expressing said exogenous sequences to alter the phenotype of the bird or to produce desired proteins. In particular, transg...	05/04/2004
6720473	Intra-vascular administration of particles to induce pulmonary hypertension, pulmonary hypertension syndrome, and ascites in poultry A new method for identifying and eliminating chickens that are susceptible to pulmonary hypertension uses micrometer scale particles to occlude blood vessels in the lungs of the chickens. This results in the death of chickens that are pre-disposed to pulmonary hyper...	04/13/2004
6563017	In vivo electroporation method for early stage embryo of chickens A gene is transferred to the early stage chicken embryo by electroporation with placing the electrode tips to hold both ends of the embryo. Transfer of the desired gene to the early stage embryo was detected using the ଲ-galactosidase gene of E coli ...	05/13/2003
6515199	Gene transfer in poultry by introduction of embryo cells in ovo A method of altering the phenotype of a bird comprises introducing a DNA sequence into somatic cells of a bird contained within an egg during in ovo incubation. The DNA sequence is selected to be effective to cause a change in phenotype, such as an increa...	02/04/2003
6395961	Gene transfer in chickens by introduction of DNA into muscle in ovo A method of altering the phenotype of a bird comprises introducing a DNA molecule into the muscle tissue of a bird contained within an egg during in ovo incubation. The DNA molecule is selected to be effective to cause a change in phenotype, such as an in...	05/28/2002
6354242	Methods for gamete production in birds A method for the production and collection of avian sperm comprises the steps of: providing primordial germ cells from a donor avian species; administering the primordial germ cells to a recipient avian species in ovo; incubating the recipient avian speci...	03/12/2002
6333192	Method of producing an undifferentiated avian cell culture using avian primordial germ cells A method of producing undifferentiated avian cells expressing an embryonic stem cell phenotype. The method includes the steps of collecting avian gonadal cells comprising primordial germ cells from an avian embryo after the formation of the primitive stre...	12/25/2001
6287863	Method of transferring a DNA sequence to a cell in vitro Improved recombinant retrotransposon vectors for gene transfer are disclosed. The synthetic vectors are truncated so as to reduce or altogether eliminate homologous recombination with retroviral helper sequences found in helper cells used to propagate the...	09/11/2001
5944652	Method for breeding chickens Disease resistance in chickens has been associated with the Rfp-Y system of major histocompatability genes in chickens. A method for breeding chickens to produce disease resistant offspring involves selecting at least one parent that has an Rfp-Y haplotyp...	08/31/1999

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Class 800/19 - Bird (e.g., chicken, etc.)