Felix Hoffmann, a German chemist, was searching for something to relieve his father's arthritis. In doing so, he "rediscovered" acetylsalicylic acid and in 1900, patented a stable process for developing it. Hence, we have aspirin.
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| Number | Title | Issue Date |
| 8132476 | Method and apparatus for handling small quantities of fluids The invention relates to a method and an apparatus for handling small quantities of fluids useful, for example, in measuring the gas and/or liquid sorption and desorption properties of substances such as hydrogen sorption by solid or liquid hydrogen storage material... | 03/13/2012 |
| 7908934 | Valve assembly A valve assembly includes a valve body having an inlet port and an outlet port, the valve body also having a valve chamber extending between the inlet port and the outlet port, a pair of seals each being located on opposing ends of the valve chamber; and a reciproca... | 03/22/2011 |
| 7823468 | Valve A sample injector includes a rotary valve element with a straight passageway through it, which element may be rotated to connect a port communicating with a source of solvent with a port communicating with an inlet to a column. Another passageway connects two adjace... | 11/02/2010 |
| 7661326 | Apparatus for aspirating and dispensing liquids in an automated analyzer Apparatus for aspirating and dispensing liquid samples in an analytical instrument, e.g., a hematology instrument, includes a liquid-sampling valve that, while operating to segment and position for dispensing one or more precise volumes of a liquid sample that has b... | 02/16/2010 |
| 7406886 | Injector An injector has a sample chamber for retaining a small amount of sample, wherein a position of the sample chamber is controlled by transmitting light through the sample chamber and detecting the transmitted light so as to recognize the position of the sample chamber... | 08/05/2008 |
| 7370672 | Diverter valve A diverter valve is disclosed and may comprise an actively cooled valve actuation section, an actuator, and a valve section comprising a rotationally actuated valve plate that is structured to be rotationally actuated by the actuator to direct flow wherein the actua... | 05/13/2008 |
| 7311882 | Capillary interconnect device A manifold for connecting external capillaries to the inlet and/or outlet ports of a microfluidic device for high pressure applications is provided. The fluid connector for coupling at least one fluid conduit to a corresponding port of a substrate that includes: (i)... | 12/25/2007 |
| 7270789 | Pipettor head having standpipes open at their tops to a pressure/vacuum chamber and method In a preferred embodiment, a pipettor head, including: a body; one or more solenoid valves disposed in the body; each one or more solenoid valves having an outlet at a lower end and an inlet at an upper end; each one or more solenoid valves having an outlet attached... | 09/18/2007 |
| 7258783 | Fluid delivery system for a water tub using a removeable chemical carrier A water tub including a fluid delivery system utilizes a removeable carrier to provide fluids to the fluid delivery system. In some instances, the carrier is disposable such that depletion of the fluids within the container results in the carrier being thrown away a... | 08/21/2007 |
| 7150994 | Parallel flow process optimization reactor Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise one or more subs... | 12/19/2006 |
| 7122156 | Parallel flow reactor having variable composition Parallel flow reaction systems comprising four or more reaction channels are disclosed. Distribution systems, and parallel flow reaction systems comprising such distribution systems are also disclosed. Specifically, the distribution systems comprise a feed-compositi... | 10/17/2006 |
| 7118917 | Parallel flow reactor having improved thermal control Parallel flow chemical processing systems, such as parallel flow chemical reaction systems are disclosed. These systems are adapted to simultaneously and independently vary temperature between separate flow channels, preferably by employing separate, individual heat... | 10/10/2006 |
| 7019541 | Electric conductivity water probe An electric conductivity water probe consisting of a test chamber having a wall, a fluids input/output port, and a water input port, the wall having a first and at least a second wall section, the first and at least second wall sections being electrically isolated f... | 03/28/2006 |
| 6971820 | Microblower assisted barometric valve A gas exchange apparatus is provided which provides for both passive fluid flow and blower associated fluid flow through a barometric valve. A battery powered blower is provided which allows for operation of the barometric valve during times when the barometric valv... | 12/06/2005 |
| 6969045 | Rotary valve The present invention relates to valves with small dead volumes. A valve in accordance with the present invention has a ferrule (7) which receives a plurality of fluid lines (33) which lead to outlets on an end surface (25) of said ferrule (7... | 11/29/2005 |
| 6966336 | Fluid injection microvalve A microvalve for extracting small volume samples into analytical devices, e.g., high pressure liquid chromatography (HPLC) column, includes: a first body having a first interior surface and two or more outlet ports at the first interior surface that are in fluid com... | 11/22/2005 |
| 6942837 | System for filling a substrate with a liquid sample A system for filling a substrate having at least one chamber with a liquid sample is provided. The system in one embodiment includes a substrate defining a network of passageways including at least one chamber for the liquid sample, and an adapter. The adapter inclu... | 09/13/2005 |
| 6918573 | Microvalve A high pressure microvalve for connecting a first fluid-bearing conduit to a second fluid-bearing conduit is provided. The microvalve includes (a) a first body having a first interior surface and at least one port outlet at the first interior surface that is in flui... | 07/19/2005 |
| 6910394 | Chromatograph valve and method of use An improved chromatograph valve is provided which may be placed in close proximity to a chromatograph in order to avoid temperature variations in the space therebetween. The valve may include a multiple sample slot rotor movable in a single direction to reduce wear ... | 06/28/2005 |
| 6872361 | Dual pad liquid shear valve assembly A shear valve assembly comprises a pair of valve pads having opposing planar surfaces supported for relative sliding engagement. Each valve pad defines a plurality of liquid pathways by which a liquid can be passed from one pad to the other. The planar surface of on... | 03/29/2005 |
| 6810756 | Sampling device A rotating plug (4) is installed in a body (1) and can be in different positions in which two lateral drillings come in front of the orifices corresponding to the body (1) or a sampling orifice (18) in front of which a flask is placed. Th... | 11/02/2004 |
| 6632404 | Automatically actuated parallel sample injector valve A sample injector valve capable of introducing multiple samples of material into multiple liquid or gas streams is provided. Such a valve is particularly useful for injecting multiple samples under pressure into a combinatorial chemistry system with movin... | 10/14/2003 |
| 6502448 | Chromatography detection system and method A chromatography detection system can handle the flow from a chromatography column. The chromatography detection system has an injection valve and a detector for detecting emissions from a flowing sample. The injection valve has at least one loop and is a... | 01/07/2003 |
| 6432265 | Sampling method and method for cleaning sampling apparatus The object of the invention is a sampling apparatus in a continuous industrial process for taking a sample of the substance to be monitored. The sampling apparatus is located on the wall of the pulp tank and it includes a sample chamber, which is equipped... | 08/13/2002 |
| 6425298 | Apparatus for passive removal of subsurface contaminants and volume flow measurement A system for improving the Baroball valve and a method for retrofitting an existing Baroball valve. This invention improves upon the Baroball valve by reshaping the interior chamber of the valve to form a flow meter measuring chamber. The Baroball valve s... | 07/30/2002 |
| 6390127 | Selection valve with ferrule cluster A multi-port injection/selection valve utilizes a ferrule cluster to connect tubes or capillaries to a common port in the valve. The use of micro ferrule clusters, as opposed to conventional connectors such as nuts and/or bolts, permits the capillary ends... | 05/21/2002 |
| 6387710 | Automated sample processor Provided is a liquid handling device comprising: a cylindrical actuator cavity in a substrate, the actuator cavity intersected by two or more actuator channels; one or more chambers with an access channel adapted to connect to a separate one of actuator c... | 05/14/2002 |
| 6276220 | Multipurpose groundwater sampler Embodiments of a multipurpose groundwater sampler device are shown and described, each having a sample tube part of which forms a sample chamber, a top portion having a handle, a novel inlet portion, a sediment trap, novel valve means and a means to join ... | 08/21/2001 |
| 6267143 | Selection valve with ferrule cluster A multi-port injection/selection valve utilizes a ferrule cluster to connect tubes or capillaries to a common port in the valve. The use of micro ferrule clusters, as opposed to conventional connectors such as nuts and/or bolts, permits the capillary ends... | 07/31/2001 |
| 6202698 | Multiple port diaphragm valve This disclosure sets forth a diaphragm valve operative with N ports deployed in an upper head. The ports all connect to a diaphragm having a bead defining a flow path around the diaphragm connecting all the ports. In the cylinder below the upper head, the... | 03/20/2001 |
| 6190616 | Capillary valve, connector, and router A capillary valve, connector and router where one or more cylindrical fibers, which may be capillaries, plugged capillaries, optical fibers, or the like, including at least one capillary tube are contained in a first cylindrical bundle of fibers that term... | 02/20/2001 |
| 5922972 | Device for taking samples on a pipeline Apparatus for obtaining a fluid sample from a flow moving through a pipeline that includes a cylindrical body mounted in the line that has the same inside diameter as the pipeline. A housing is attached to the body which communicates therewith through an ... | 07/13/1999 |
| 5814742 | Fully automated micro-autosampler for micro, capillary and nano high performance liquid chromatography A liquid chromatography micro-autosampler is disclosed that permits the sampling of very small samples quantities at high accuracy, while minimizing extracolumn band broadening. The autosampler employ a sample intake tubing connected to the injection valv... | 09/29/1998 |
| 5776418 | Automated analysis apparatus having fixed cells An apparatus is proposed making it possible in automated manner to perform several analyses on the same sample. For this purpose several fixed, chemical preparation cells (10) can separately receive several fractions of the same sample. Reagent injection ... | 07/07/1998 |
| 5763795 | Sampling apparatus A sample apparatus includes a sampling valve having a sample inlet through which a sample such as urine is introduced from the outside of the sampling valve to the inside thereof; a sample outlet through which the sample is sent from the inside of the sam... | 06/09/1998 |
| 5750906 | Multifunction valve The invention features a sample probe and reagent selector valve that enables selection among multiple functions of withdrawing a biological sample from a syringe or capillary into a fluid parameter sensor module, providing calibration and quality control... | 05/12/1998 |
| 5691486 | Apparatus and methods for selecting a variable number of test sample aliquots to mix with respective reagents A method and apparatus for selecting a subset of a predetermined number of test sample aliquots to mix with respective reagents using a shear valve having a maximum predetermined number of aliquot loops in an analytical instrument, including without limit... | 11/25/1997 |
| 5650577 | Liquid sampling valve A liquid sampling valve includes a fixed element having a contact surface and a movable element having a contact surface for contacting the contact surface of the fixed element; the fixed element or the movable element having measuring passageways extendi... | 07/22/1997 |
| 5542305 | Liquid metering and transfer valve assembly particularly for flow cytometer A metering and transfer valve assembly particularly for use in particle analyzing apparatus for the study of particles in liquid suspension, the valve assembly having at least pair of inner and outer valve elements coaxially arranged in face to face frict... | 08/06/1996 |
| 5524496 | Liquid sampling valve A liquid sampling valve includes a fixed element having a contact surface and a movable element having a contact surface for contacting the contact surface of the fixed element; the fixed element or the movable element having measuring passageways extendi... | 06/11/1996 |