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| Number | Title | Issue Date |
| 7437913 | Method and device for analysing a liquid Novel methods and devices comprising magnetic particles for detecting or monitoring the coagulation state of a sample are provided. ... | 10/21/2008 |
| 7439069 | Blood coagulation test cartridge, system, and method A system and method for determining a coagulation time, e.g., thrombin time, PT, aPTT, and ACT, of a blood sample deposited in a test cartridge is disclosed. The test cartridge includes a blood receptacle that is open to the atmosphere into which a blood sample is t... | 10/21/2008 |
| 7422905 | Blood coagulation test cartridge, system, and method A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major sides and a minor sidewall encloses a test chamber having a test chambe... | 09/09/2008 |
| 7399637 | Blood coagulation test cartridge, system, and method A system and method for determining a coagulation time, e.g., TT, PT, aPTT, and ACT, of a blood test sample deposited in a test cartridge is disclosed. A cartridge housing having upper and lower major sides and a minor sidewall encloses a test chamber having a test ... | 07/15/2008 |
| 7361306 | Device and method for measuring coagulation time and platelet activity The present invention refers to a novel device for measuring coagulation time and platelet activity wherein the patient can measure his or her coagulation time and platelet activity without the aid of medical professionals due to the fact that this device is fully a... | 04/22/2008 |
| 7335335 | Apparatus and method to measure platelet contractility An apparatus and method for measuring blood platelet contractility, hereinafter called a “retractometer” is disclosed. Also disclosed is a system apparatus and method for automatically measuring platelet contractility in a plurality of samples, having an array o... | 02/26/2008 |
| 7314596 | Apparatus for sensing coagulation of blood sample A blood sample sensing apparatus includes a moving device which moves a sample container containing a blood sample to a sensing position, a turning mechanism which is connected to the moving device and tilts the sample container such that a bottom of the sample cont... | 01/01/2008 |
| 7291310 | Microsystem for determining clotting time of blood and low-cost, single-use device for use therein A microsystem for determining clotting time of blood and a low-cost, single-use device for use therein are provided wherein the device has no moving parts or expensive optical sensors or magnets. The device includes a microfluidic channel and a microsensor at least ... | 11/06/2007 |
| 7276376 | Analyzing method of a blood coagulation reaction An analyzing method of a blood coagulation reaction by detecting an optical change of a blood sample with an elapse of time, the method includes: setting at least one checkpoint or check region between a starting point of the blood coagulation reaction and the endpo... | 10/02/2007 |
| 7276377 | Method and apparatus for determining anticoagulant therapy factors Methods and apparatus are disclosed for determining a new anticoagulant therapy factor (nATF) for monitoring oral anticoagulant therapy to help prevent excessive bleeding or deleterious blood clots that might otherwise occur before, during or after surgery. In one e... | 10/02/2007 |
| 7261861 | Hemostasis analyzer and method A method and device for blood hemostasis analysis is disclosed. A blood sample is displaced to reach a resonant state. The resonant frequency of the blood sample is determined before, during and after a hemostasis process. The changes in the resonant frequency of th... | 08/28/2007 |
| 7247488 | Method and kit for testing a multi-channel blood assay cartridge A method and kit for testing a multi-channel blood-testing cartridge. In particular, blood-testing cartridges are tested with plasma samples with clotting times measured to indicate whether a batch of cartridges is suitable for testing the blood of a patient. ... | 07/24/2007 |
| 7235213 | System for performing blood coagulation assays and measuring blood clotting times A system for performing a blood coagulation assay, having: a reaction chamber; at least one moveable member configured to mix contents of the reaction chamber; a sensor configured to detect the presence of a blood clot formed in the reaction chamber; and a timer tha... | 06/26/2007 |
| 7211438 | Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample Methods for predicting the presence of haemostatic dysfunction in a patient from a time-dependent measurement profile include performing a time-dependent measurement on an unknown sample and measuring a respective property over time so as to derive a time-dependent ... | 05/01/2007 |
| 7192726 | Method of using platelet contractile force and whole blood clot elastic modulus as clinical markers Platelet contractile force and/or clot elastic modulus measurements are used to identify patients at risk for atherosclerosis or for bleeding during surgical procedures or other applications. Measurements which are elevated are indicative of atherosclerosis, and mea... | 03/20/2007 |
| 7182913 | Sample retention apparatus for use in measuring hemostasis A sample retention apparatus for use in a device for measuring hemostasis. The device for measuring hemostasis may include a sample articulation apparatus including a guide shaft coupled for articulating motion to a drive motor, a sample carrier secured to and axial... | 02/27/2007 |
| 7179652 | Protocol for monitoring platelet inhibition A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation, through platelet-fibrin interaction and lysis to generate blood hemostasis ... | 02/20/2007 |
| 7150996 | Stability assessment of dispersions and emulsions A method and apparatus for determining the stability of dispersions and emulsions accelerates the onset of significant particle agglomeration in a sample by stressing the sample by reducing the height of the interparticle potential energy barrier between the particl... | 12/19/2006 |
| 7117721 | Fluid dose, flow and coagulation sensor for medical instrument In combination, an instrument for determining a characteristic of a biological fluid or a control, and a cuvette for holding a sample of the biological fluid or control, the characteristic of which is to be determined. The instrument comprises a radiation-reflective... | 10/10/2006 |
| 7029628 | Portable co-oximeter The invention discloses a system, method and medical device for measuring various hemoglobin derivatives, such as oxyhemoglobin, reduced hemoglobin, partial hemoglobin, carboxyhemoglobin, methemoglobin and sulfhemoglobin in whole or in hemolyzed blood. The novel met... | 04/18/2006 |
| 6955923 | Device and method for investigating the flowability of a physiological fluid sample To investigate the flowability of a physiological fluid sample, an uptake passage (12) for the fluid sample (16), an actuator device (18) for the cyclic change in orientation of measuring particles (14) in the fluid sample (16), an... | 10/18/2005 |
| 6942859 | Red blood cells covalently bound with polymers Living cells modified at their surface with specially selected polymers are disclosed. A simple method to covalently attach specially selected PEG derivatives to the surface of RBC in aqueous media under mild conditions is a preferred example. The selected PEG-modif... | 09/13/2005 |
| 6889539 | Low disturbance pulsatile flow system A flow system device used for testing/creating fluid flow. The system comprises at least one fluid filled loop and a rotor stage for maintaining at least one rotor. The loop is positioned on the rotor. The device also includes a driving motor for rotating the rotor ... | 05/10/2005 |
| 6872572 | Method of platelet function analysis using platelet count A method for determining platelet activation by utilizing numeric counts of platelets before a sample of platelets has been activated and after the activatable platelets are activated with a platelet activation agonist and using the difference between such counts as... | 03/29/2005 |
| 6849456 | Test strip qualification system In connection with a fluidic medical diagnostic device that permits measurement of the coagulation time of blood, software, methods and associated devices for quality control are provided. The fluidic device preferably includes a test strip with one end having a sam... | 02/01/2005 |
| 6835570 | Test strip qualification system In connection with a fluidic medical diagnostic device that permits measurement of the coagulation time of blood, software, methods and associated devices for quality control are provided. The fluidic device preferably includes a test strip with one end having a sam... | 12/28/2004 |
| 6787363 | Method and apparatus for hemostasis and blood management A procedure for hemostasis and blood management, particularly for cardiovascular procedures, provides: sampling instructions, i.e., when to draw blood samples and how to pre-treat the blood samples, a decision tree to assist the interpretation of hemostasis analysis... | 09/07/2004 |
| 6773923 | Induced aggregation and agglutination of platelets The invention relates to a method for measuring the aggregation or agglutination of platelets, where a reaction mixture is mixed in a first reaction phase, and is mixed less vigorously or not at all in a second reaction phase following the first, and the measurement... | 08/10/2004 |
| 6759009 | Method and device for clotting time assay A self-contained analyzer quantitatively detects a clotting event in a biological fluid. The device includes a base having an open reservoir for receiving the biological fluid. A carrier for a dried activator reagent is located in or adjacent to the open reservoir. ... | 07/06/2004 |
| 6746872 | Control compositions and methods of use for coagulation tests Compositions, methods, devices and kits for use in the calibration of coagulation tests. The control compositions include particles capable of aggregating in plasma and calcium ions which, when mixed with plasma, simulate the behavior of whole blood in a coagulation... | 06/08/2004 |
| 6699718 | Method, reagent and test cartridge for determining clotting time The invention is a method, reagent and test cartridge for the determination of the clotting time of a blood sample by means of a reagent containing tissue factor and a sulfatide. In an alternative embodiment, the reagent may contain tissue factor and at l... | 03/02/2004 |
| 6686204 | Collection device The present invention is a container assembly that includes a coating composition on an interior surface of the container assembly and more particularly a coating composition for rapid clotting of a blood sample within a blood collection tube. The coating... | 02/03/2004 |
| 6682933 | Test strip qualification system In connection with a fluidic medical diagnostic device that permits measurement of the coagulation time of blood, software, methods and associated devices for quality control are disclosed. The fluidic device preferably includes a test strip with one end ... | 01/27/2004 |
| 6676902 | Method and device for testing a sample of fresh whole blood A method and device for testing a sample of fresh whole blood. In particular the present invention provides a method and device for testing a sample of fresh whole blood to determine whether a patient would benefit from the administration of a blood facto... | 01/13/2004 |
| 6673617 | Test strip qualification system In connection with a fluidic medical diagnostic device that permits measurement of the coagulation time of blood, software, methods and associated devices for quality control are disclosed. The fluidic device preferably includes a test strip with one end ... | 01/06/2004 |
| 6632678 | Method for performing activated clotting time test with reduced sensitivity to the presence of aprotinin and for assessing aprotinin sensitivity A coagulation test for determining the activated clotting time (ACT) of blood in the presence of heparin that produces test results that are substantially insensitive to the drug aprotinin. The activator is formulated to be a combination of celite and ben... | 10/14/2003 |
| 6617166 | Measurement of accelerated whole blood clotting time Disclosed is The method of in vitro testing of the state of the blood coagulation system. The Accelerated Whole Blood Clotting Time (A. W. B. C. T.) reflects the degree of over or under activity of the coagulation system of the blood.... | 09/09/2003 |
| 6613573 | Method and apparatus for monitoring anti-platelet agents A blood coagulation analyzer, such as the Thrombelastograph.RTM. (TEG.RTM.) blood coagulation analyzer is utilized to measure continuously in real time, the clotting process from the initial fibrin formation, through platelet-fibrin interaction and lysis ... | 09/02/2003 |
| 6566140 | Inhibition of coagulation in blood and blood products The present invention provides methods for inhibiting blood clotting. In general, the methods include adding corn trypsin inhibitor (CTI) to blood or a blood product in an amount sufficient to inhibit the clotting. The CTI can be used alone or in combinat... | 05/20/2003 |
| 6541262 | Method and device for testing a sample of fresh whole blood A method and device for testing a sample of fresh whole blood. In particular the present invention provides a method and device for testing a sample of fresh whole blood to determine whether a patient would benefit from the administration of a blood facto... | 04/01/2003 |