Did You Know...
...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.
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| Number | Title | Issue Date |
| 8109994 | Biodegradable drug delivery material for stent A stent is fabricated utilizing a polymer that is selected for its tendency to degrade from the surface inwardly rather than undergo bulk erosion so as to substantially reduce the risk of large particles becoming detached and being swept downstream. Such polymer is ... | 02/07/2012 |
| 8105374 | Vascular stents The disclosure describes a coating for medical implants, in particular, vascular stents, said coating comprising silicon dioxide, towards medical implants with a coating containing silicon dioxide and towards a method for their production. The coating can contain ad... | 01/31/2012 |
| 8075612 | Textile vascular prosthesis with a coating Textile vascular prostheses having a coating include an absorbable polymer in the form of a three-armed polyester having terminal hydroxyl groups from hydroxy acids polymerized onto a central trifunctional hydroxy compound, the three arms being tetrapolymers of lact... | 12/13/2011 |
| 8066764 | Stent coating for eluting medication A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assemb... | 11/29/2011 |
| 8057536 | Implant having a surface-proximal magnesium-containing diffusion layer and associated production method An implant comprising an implant material forming a base made of one or more metallic elements; a diffusion layer covering the base made of at least one of the metallic elements of the implant material and at least magnesium; and, optionally, a metal layer covering ... | 11/15/2011 |
| 8052746 | Balloon expandable stent The present invention relates to a balloon expandable stent mounted on a balloon catheter, the entire assembly being overcoated with a coherent polymer coating, which is preferably substantially continuous over the circumference and, more preferably, axial length of... | 11/08/2011 |
| 8016881 | Sutures and surgical staples for anastamoses, wound closures, and surgical closures The invention relates to sutures and surgical staples useful in anastomoses. Various aspects of the invention include wound closure devices that use amphiphilic copolymer or parylene coatings to control the release rate of an agent, such as a drug or a biological ma... | 09/13/2011 |
| 8002822 | Radiopaque coating for biomedical devices A medical device has a porous radiopaque coating that can withstand the high strains inherent in the use of such devices without delamination. A coating of Ta is applied to a medical device, such as a stent, by vapor deposition so that the thermomechanical propertie... | 08/23/2011 |
| 8002823 | Endoprosthesis coating An endoprosthesis, such as a stent, includes anchoring regions formed of polymer that enhance adherence of a coating, e.g. a drug eluting polymer coating, to a stent surface, e.g. made of ceramic. The anchoring regions can be formed using stamping processes. ... | 08/23/2011 |
| 7985252 | Bioerodible endoprosthesis An endoprosthesis includes a plurality of struts defining a flow passage. At least one strut includes (a) a body comprising a bioerodible material and having a thickness and (b) a coating overlying the body. The coating includes a plurality of regions that allow phy... | 07/26/2011 |
| 7959671 | Differential covering and coating methods The present invention, in an exemplary embodiment, provides a stent, which combines many of the excellent characteristics of both silicone and metal stents while eliminating the undesirable ones. In particular, a principal objective in accordance with the present in... | 06/14/2011 |
| 7942926 | Endoprosthesis coating An endoprosthesis, such as a stent, includes a chemical tie layer formed of polymer that enhance adherence of a coating, e.g. a drug eluting polymer coating, to a stent surface, e.g. made of ceramic. ... | 05/17/2011 |
| 7938855 | Deformable underlayer for stent An endoprosthesis includes a brittle layer, e.g. a ceramic and an underlayer to accommodate dimensional changes as the endoprosthesis is flexed. ... | 05/10/2011 |
| 7927368 | Device viewable under an imaging beam The invention provides a stent made from a material operable to perform a stent's desired therapeutic functions, and also made from a material that has a radiopacity that substantially preserves the appearance of the stent when the stent is viewed under a CT imaging... | 04/19/2011 |
| 7892280 | Implantable medical devices with fluorinated polymer coatings, and methods of coating thereof An implantable medical device including an expandable stent with an amorphous fluoropolymer coating, and methods of coating the stent. The amorphous fluoropolymer coating may be optically transparent and resistant to chemical corrosion. ... | 02/22/2011 |
| 7879086 | Medical device having a coating comprising an adhesion promoter This invention is directed to a coating for a medical device, such as an intravascular stent, in which the coating, which comprises a first coating region comprising an adhesion promoter and a therapeutic agent. The coating can also include a second coating region w... | 02/01/2011 |
| 7819914 | Adhesion promoting primer for coated surfaces An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a first diameter to a second diameter. A plurality of different beneficial agents may be loaded into different openings within ... | 10/26/2010 |
| 7803183 | Medical device with coating that promotes endothelial cell adherence A medical device with a coating for capturing target cells in vivo is provided. In particular, the medical device is coated with at least one layer of matrix and a layer of antibodies, antibody fragments or combinations thereof, which bind with specificity to mature... | 09/28/2010 |
| 7744645 | Laminated drug-polymer coated stent with dipped and cured layers The present invention provides a method of applying a drug-polymer coating on a stent. A stent framework is dipped into a first polymeric solution including a first polymer, a first therapeutic agent, and a first solvent. The polymeric solution is dried and the firs... | 06/29/2010 |
| 7727275 | Drug-delivery endovascular stent and method of forming the same An intravascular stent and method for inhibiting restenosis, following vascular injury, is disclosed. The stent has an expandable, linked-filament body and a drug-release coating formed on the stent-body filaments, for contacting the vessel injury site when the sten... | 06/01/2010 |
| 7708774 | Polyethylene oxide and silicone copolymers and their usage on medical devices An implantable medical device includes a device body at least partially formed of a polymeric material including a base polymer and a block copolymer. The block copolymer includes at least one polyethylene oxide (PEO) block and at least one silicone (SI) block, wher... | 05/04/2010 |
| 7678143 | Ethylene-carboxyl copolymers as drug delivery matrices A coated stent is provided including a coating composed of one or more co-polymers of ethylene with carboxylic acid wherein the carboxylic acid co-monomer content is 5-50 wt %. ... | 03/16/2010 |
| 7658761 | Balloon expandable superelastic stent A balloon expandable superelastic stent is made of a Ti—Ni—Nb (the content of Nb being at least 3 at %) shape memory alloy. A shape recovery temperature of the stent is lower than a living body temperature in an unloaded state after shape memory treatment. The s... | 02/09/2010 |
| 7637942 | Coated stent with geometry determinated functionality and method of making the same The present invention, in an exemplary embodiment, provides a stent, which combines many of the excellent characteristics of both silicone and metal stents while eliminating the undesirable ones. In particular, a principal objective in accordance with the present in... | 12/29/2009 |
| 7618448 | Polymeric, degradable drug-eluting stents and coatings Absorbable stents and absorbable stent coatings have been developed with improved properties. These devices preferably comprise biocompatible copolymers or homopolymers of 4-hydroxybutyrate, and optionally poly-L-lactic acid and other absorbable polymers and additiv... | 11/17/2009 |
| 7604662 | Endoprostheses containing boride intermetallic phases An endoprosthesis including an alloy having a matrix comprising titanium, niobium, or a combination thereof and a plurality of boride intermetallic phases within the matrix. ... | 10/20/2009 |
| 7582112 | Metal stent with surface layer of noble metal oxide and method of fabrication In a process for producing a biocompatible stent, a tubular substrate of the stent adapted for diametric expansion has a layer of a noble metal oxide formed over at least the outer surface of greater diameter of the substrate, the substrate being composed of a metal... | 09/01/2009 |
| RE40816 | Biocompatible crosslinked coating and crosslinkable coating polymer composition for forming such a coating A braided stent (1) for transluminal implantation in body lumens is self-expanding and has a radial expanded configuration in which the angle α between filaments is acute. Some or all of filaments (6,7) are welded together in pairs at each end (4,5... | 06/30/2009 |
| 7476246 | Implantable medical devices with fluorinated polymer coatings, and methods of coating thereof The present invention generally relates to implantable medical devices having a fluorinated coating, and methods of coating the same. More particularly, the present invention provides implantable metallic medical devices coated with a corrosion resistant coating com... | 01/13/2009 |
| 7470283 | Biodegradable drug delivery material for stent A stent is fabricated utilizing a polymer that is selected for its tendency to degrade from the surface inwardly rather than undergo bulk erosion so as to substantially reduce the risk of large particles becoming detached and being swept downstream. Such polymer is ... | 12/30/2008 |
| 7441513 | Plasma-generated coating apparatus for medical devices and a method of coating deposition An apparatus for plasma polymerize coating of medical devices, such as stents, is disclosed. A method for forming plasma-polymerized coating for implantable medical devices is also disclosed. ... | 10/28/2008 |
| 7442205 | Stents and methods for preparing stents from wires having hydrogel coating layers thereon Radially expandable stents having hydrogel coating layers thereon, and methods of preparing such stents are disclosed. The methods include coating a wire with a solution that includes a solvent and a water soluble polymer in the solvent, evaporating the solvent to p... | 10/28/2008 |
| 7438722 | Method for treatment of restenosis A method for inhibiting restenosis is described. The method comprises implanting a stent in a patient's vasculature and simultaneously delivering a restenosis-inhibiting medicine to the treatment site by adjuvant therapy. ... | 10/21/2008 |
| 7435256 | Method and apparatus for controlled delivery of active substance The invention relates to a method and device for coating a device with time-release drugs by providing a plurality of micro coated pellets having different release rates on the surface of the medical device structure, e.g., a stent. Organizing the micro pellets with... | 10/14/2008 |
| 7419709 | Polymer coating for medical devices Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a poly... | 09/02/2008 |
| 7419504 | Poly(ester amide) block copolymers Provided herein is a copolymer that includes a soft block (A) that contains poly(ester amide) (PEA) and a hard block (B). The copolymer can be any of AB, ABA or BAB type block copolymers. By varying the relative amount of the PEA block and the hard block, one can ob... | 09/02/2008 |
| 7416559 | Micromantled drug-eluting stent Pharmacologically active, easy-to-deploy, biomechanically compatible, inflatable endovascular, drug-eluting stent are formed of a primary expandable polymeric or metallic construct, intimately mantled with a biomechanically compatible, polymeric microporous, microfi... | 08/26/2008 |
| 7402173 | Metal stent with surface layer of noble metal oxide and method of fabrication In a process for producing a biocompatible stent, a tubular substrate of the stent adapted for diametric expansion has a layer of a noble metal oxide formed over at least the outer surface of greater diameter of the substrate, the substrate being composed of a metal... | 07/22/2008 |
| 7390333 | Biodegradable drug delivery material for stent A stent is fabricated utilizing a polymer that is selected for its tendency to degrade from the surface inwardly rather than undergo bulk erosion so as to substantially reduce the risk of large particles becoming detached and being swept downstream. Such polymer is ... | 06/24/2008 |
| 7377939 | Highly convertible endolumenal prostheses and methods of manufacture Endolumenal prostheses that readily and extensively convert from a delivery configuration to a deployed configuration are disclosed. Endolumenal prostheses may be fabricated from one or more shape memory polymers, a high modulus elastomer, a polymer that is both ela... | 05/27/2008 |
