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| Number | Title | Issue Date |
| 8070798 | Drug eluting medical device and method A drug elution stent includes a stent framework and a drug elution portion disposed on the stent framework. The drug elution portion includes a first sugar layer disposed on the stent framework, at least one therapeutic agent layer disposed on the first sugar layer ... | 12/06/2011 |
| 8062353 | Abluminal, multilayer coating constructs for drug-delivery stents Implantable medical devices may include at least one structural element having an abluminal side, luminal side, and sidewalls between the abluminal and luminal sides. The coating may include at least two continuous coating layers. In some embodiments, the luminal si... | 11/22/2011 |
| 8048151 | Stent coating for eluting medication A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assemb... | 11/01/2011 |
| 8029563 | Implantable devices with reduced needle puncture site leakage A prosthetic implantable device that offers a reduction in fluid loss when the device is punctured, such as by a dialysis needle or suture needle, and the needle is subsequently removed. The device may be made to be thin and flexible, and with longitudinal stretch, ... | 10/04/2011 |
| 7993391 | Medical devices and methods of making the same Medical devices, for example, implantable devices such as endoprostheses, include a composite material having a polymer. ... | 08/09/2011 |
| 7993390 | Implantable or insertable medical device resistant to microbial growth and biofilm formation Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable o... | 08/09/2011 |
| 7972375 | Endoprostheses including metal matrix composite structures An endoprosthesis that includes a composite having a metal matrix and a plurality of stiffening particles in the matrix. The metal of the metal matrix can include titanium, niobium, tantalum, or alloys thereof. The stiffening particles can include a metal core and a... | 07/05/2011 |
| 7955383 | Laminated implantable medical device having a metallic coating A laminated stent encapsulated with a metal coating is provided. The metal coating may be a very thin metal coating. Portions of the metal coating may be removed such that the metal coating covers voids in the laminate, particularly in the area where the different l... | 06/07/2011 |
| 7951194 | Bioabsorbable stent with radiopaque coating Various embodiments of stents with a bioabsorbable body having a coating with a radiopaque layer are disclosed. ... | 05/31/2011 |
| 7947073 | Resorption-controllable medical implants Bioresorbable medical implants are designed to have different resorption rates over time or over the topography of the implants. The resorption of the medical implants are controlled by including layers having differing resorption rates. The layers resorb sequential... | 05/24/2011 |
| 7922761 | Artificial vascular prosthesis A vascular prosthesis having a tubular structure is provided. The tubular structure is fabricated from at least two layers wherein at least one layer includes a thrombogenic agent. ... | 04/12/2011 |
| 7914574 | Axially nested slide and lock expandable device The invention relates generally to expandable medical implants for maintaining support of a body lumen and, in particular, to an axially nested, diametrically expandable, slide and lock vascular device for enlarging an occluded portion of a vessel. The axially neste... | 03/29/2011 |
| 7837726 | Visible endoprosthesis A crack-resistant endoprosthesis for delivery in a body lumen can be comprised of a multilayered material. The multilayered material can include at least two layers having a boundary layer therebetween. The boundary layer is configured to inhibit cracks from propaga... | 11/23/2010 |
| 7828840 | Medical devices and methods for local delivery of angiotensin II type 2 receptor antagonists This invention relates to medical devices and an angiotensin II type 2 (AT2) receptor antagonist compound, the medical device being adapted to release the AT2 receptor antagonist compound within a body of a patient. This invention also relates ... | 11/09/2010 |
| 7806925 | Biodegradable drug delivery vascular stent A stent includes a main body of a generally tubular shape for insertion into a lumen of a vessel of a living being. The tubular main body includes a substantially biodegradable matrix having collagen IV and laminin that enclose voids within the matrix. The tubular m... | 10/05/2010 |
| 7799071 | Thread for vascular stent and vascular stent using the thread A thread for forming a vascular stent implanted in vessels is provided. This thread is formed by melt-spinning a biodegradable polymer. On the surface of the thread, there is formed a layer of a drug-containing biodegradable polymer of the same sort as the biodegrad... | 09/21/2010 |
| 7771468 | Medicated stent having multi-layer polymer coating This invention relates to stents having medicated multi-layer hybrid polymer coatings, useful for the treatment of stenosed vasculature or other body passages. ... | 08/10/2010 |
| 7749265 | Radio frequency antenna for a wireless intravascular medical device A radio frequency antenna is provided for use with a medical device for implantation into an animal. The antenna comprises a coil formed by a wire that includes a core formed of a shape-memory material with an electrically conductive first layer applied to an outer ... | 07/06/2010 |
| 7699890 | Medicated porous metal prosthesis and a method of making the same A porous prosthesis for delivering a medication to the site of implantation, and a method of making the same, is disclosed. ... | 04/20/2010 |
| 7632307 | Abluminal, multilayer coating constructs for drug-delivery stents Embodiments of coatings for implantable medical devices, such as stents, are disclosed. The devices may include at least one structural element having an abluminal side, luminal side, and sidewalls between the abluminal and luminal sides. The coating may include at ... | 12/15/2009 |
| 7608101 | Resorption-controllable medical implants Bioresorbable medical implants are designed to have different resorption rates over time or over the topography of the implants. The resorption of the medical implants are controlled by including layers having differing resorption rates. The layers resorb sequential... | 10/27/2009 |
| 7485141 | Method of placing a tubular membrane on a structural frame The present invention relates to a medical device, and more particularly to a method of forming a tubular membrane on a radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun o... | 02/03/2009 |
| 7452374 | AV grafts with rapid post-operative self-sealing capabilities The invention provides a self-sealing arteriovenous graft including a tube having a polymeric inner layer defining a lumen through which blood may flow and an outer textile layer. The outer textile layer is concentrically disposed about the inner layer. Furthermore,... | 11/18/2008 |
| 7419709 | Polymer coating for medical devices Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a poly... | 09/02/2008 |
| 7410498 | Polymeric stents and other surgical articles A biocompatible non-memory expandable polymeric article selected from stents, implantable prostheses, catheters, other surgical articles and sealants for implantable prostheses, and which is at least in part biodegradable and includes a combination where hollow cyli... | 08/12/2008 |
| 7393359 | Expandable multi-layer tubular structure and production method thereof The invention relates to a radially expandable multi-layer tubular structure which is intended to be used as a stent and to the production method thereof. The inventive structure comprises an outer layer (1) and an inner layer (2) which are solidly con... | 07/01/2008 |
| 7387641 | Self-expanding stent In an inventive stent (10), helical filaments (12, 13) are disposed on a first tubular layer (11). The helical filaments (12, 13) are mutually phase-shifted such that they do not touch and lie in one plane. The helical filaments (12, 1... | 06/17/2008 |
| 7384428 | Method and apparatus for covering a stent An expandable stent suitable for implantation in a lumen is covered with a biological material. In one embodiment, biological fibers are interwoven to form a stent covering. The fibers are disposed at an angle with respect to the longitudinal axis of the stent so th... | 06/10/2008 |
| 7371258 | Valved prosthesis with porous substrate An implantable prosthesis can be formed from an improved biocompatible material that provides for cellular colonization of the biocompatible material. Specifically, the biocompatible material is a rigid porous material. In embodiments of particular interest, the imp... | 05/13/2008 |
| 7371400 | Multilayer device for tissue engineering The invention provides for translating two-dimensional microfabrication technology into the third dimension. Two-dimensional templates are fabricated using high-resolution molding processes. These templates are then bonded to form three-dimensional scaffold structur... | 05/13/2008 |
| 7367990 | Thread for vascular stent and vascular stent using the thread A thread for forming a vascular stent implanted in vessels is provided. This thread is formed by melt-spinning a biodegradable polymer. On the surface of the thread, there is formed a layer of a drug-containing biodegradable polymer of the same sort as the biodegrad... | 05/06/2008 |
| 7354480 | Stent mandrel fixture and system for reducing coating defects A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. ... | 04/08/2008 |
| 7351421 | Drug-eluting stent having collagen drug carrier chemically treated with genipin A method for treating vulnerable plaques of a patient, comprising: providing a biodegradable stent comprising a first supporting zone made of a first biodegradable material, wherein the supporting zone comprises at least a portion of continuous circumference of the ... | 04/01/2008 |
| 7341630 | Stent coating system A nozzle for use in a coating apparatus for the application of a solvent and polymer to a stent is provided. ... | 03/11/2008 |
| 7335258 | Functionalization and separation of nanotubes and structures formed thereby Methods of forming a microelectronic structure are described. Embodiments of those methods include attaching at least one functional group to a chondroitin sulfate molecule, and then attaching the at least one functional group to a carbon nanotube, wherein the carbo... | 02/26/2008 |
| 7335229 | Vascular stent with composite structure for magnetic resonance imaging capabilities A stent is adapted to be implanted in a duct of a human body to maintain an open lumen at the implant site, and to allow viewing body tissue and fluids by magnetic resonance imaging (MRI) energy applied external to the body. The stent constitutes a metal scaffold. A... | 02/26/2008 |
| 7335314 | Method of making an implantable medical device An implantable medical device, such as a stent or graft, having asperities on a designated region of its outer surface is disclosed. The asperities can serve to improve retention of one or more layers of a coating on the device and to increase the amount of coating ... | 02/26/2008 |
| 7331992 | Anchoring device for an endoluminal prosthesis An anchoring device for incorporation into an endoluminal prosthesis to prevent migration thereof in a reliable way without the problems associated with intraluminal delivery of the prosthesis. The anchoring device allows smooth, efficient delivery of the prosthesis... | 02/19/2008 |
| 7329277 | Stent having helical elements An expandable stent comprised of a plurality of helical segments is disclosed. In one embodiment, the stent is generally cylindrical in shape having a cylindrical axis, and comprises a first and second set of helical segments. The helical segments in the first set a... | 02/12/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |