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| Number | Title | Issue Date |
| 7632307 | Abluminal, multilayer coating constructs for drug-delivery stents Embodiments of coatings for implantable medical devices, such as stents, are disclosed. The devices may include at least one structural element having an abluminal side, luminal side, and sidewalls between the abluminal and luminal sides. The coating may include at ... | 12/15/2009 |
| 7608101 | Resorption-controllable medical implants Bioresorbable medical implants are designed to have different resorption rates over time or over the topography of the implants. The resorption of the medical implants are controlled by including layers having differing resorption rates. The layers resorb sequential... | 10/27/2009 |
| 7485141 | Method of placing a tubular membrane on a structural frame The present invention relates to a medical device, and more particularly to a method of forming a tubular membrane on a radially expandable structural frame. In one aspect, a structural frame is placed over a spinning mandrel and a fiber is electro-statically spun o... | 02/03/2009 |
| 7452374 | AV grafts with rapid post-operative self-sealing capabilities The invention provides a self-sealing arteriovenous graft including a tube having a polymeric inner layer defining a lumen through which blood may flow and an outer textile layer. The outer textile layer is concentrically disposed about the inner layer. Furthermore,... | 11/18/2008 |
| 7419709 | Polymer coating for medical devices Coatings are provided in which surfaces may be activated by covalently bonding a silane derivative to the metal surface, covalently bonding a lactone polymer to the silane derivative by in situ ring opening polymerization, and depositing at least one layer of a poly... | 09/02/2008 |
| 7410498 | Polymeric stents and other surgical articles A biocompatible non-memory expandable polymeric article selected from stents, implantable prostheses, catheters, other surgical articles and sealants for implantable prostheses, and which is at least in part biodegradable and includes a combination where hollow cyli... | 08/12/2008 |
| 7393359 | Expandable multi-layer tubular structure and production method thereof The invention relates to a radially expandable multi-layer tubular structure which is intended to be used as a stent and to the production method thereof. The inventive structure comprises an outer layer (1) and an inner layer (2) which are solidly con... | 07/01/2008 |
| 7387641 | Self-expanding stent In an inventive stent (10), helical filaments (12, 13) are disposed on a first tubular layer (11). The helical filaments (12, 13) are mutually phase-shifted such that they do not touch and lie in one plane. The helical filaments (12, 1... | 06/17/2008 |
| 7384428 | Method and apparatus for covering a stent An expandable stent suitable for implantation in a lumen is covered with a biological material. In one embodiment, biological fibers are interwoven to form a stent covering. The fibers are disposed at an angle with respect to the longitudinal axis of the stent so th... | 06/10/2008 |
| 7371400 | Multilayer device for tissue engineering The invention provides for translating two-dimensional microfabrication technology into the third dimension. Two-dimensional templates are fabricated using high-resolution molding processes. These templates are then bonded to form three-dimensional scaffold structur... | 05/13/2008 |
| 7371258 | Valved prosthesis with porous substrate An implantable prosthesis can be formed from an improved biocompatible material that provides for cellular colonization of the biocompatible material. Specifically, the biocompatible material is a rigid porous material. In embodiments of particular interest, the imp... | 05/13/2008 |
| 7367990 | Thread for vascular stent and vascular stent using the thread A thread for forming a vascular stent implanted in vessels is provided. This thread is formed by melt-spinning a biodegradable polymer. On the surface of the thread, there is formed a layer of a drug-containing biodegradable polymer of the same sort as the biodegrad... | 05/06/2008 |
| 7354480 | Stent mandrel fixture and system for reducing coating defects A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. ... | 04/08/2008 |
| 7351421 | Drug-eluting stent having collagen drug carrier chemically treated with genipin A method for treating vulnerable plaques of a patient, comprising: providing a biodegradable stent comprising a first supporting zone made of a first biodegradable material, wherein the supporting zone comprises at least a portion of continuous circumference of the ... | 04/01/2008 |
| 7341630 | Stent coating system A nozzle for use in a coating apparatus for the application of a solvent and polymer to a stent is provided. ... | 03/11/2008 |
| 7335258 | Functionalization and separation of nanotubes and structures formed thereby Methods of forming a microelectronic structure are described. Embodiments of those methods include attaching at least one functional group to a chondroitin sulfate molecule, and then attaching the at least one functional group to a carbon nanotube, wherein the carbo... | 02/26/2008 |
| 7335314 | Method of making an implantable medical device An implantable medical device, such as a stent or graft, having asperities on a designated region of its outer surface is disclosed. The asperities can serve to improve retention of one or more layers of a coating on the device and to increase the amount of coating ... | 02/26/2008 |
| 7335229 | Vascular stent with composite structure for magnetic resonance imaging capabilities A stent is adapted to be implanted in a duct of a human body to maintain an open lumen at the implant site, and to allow viewing body tissue and fluids by magnetic resonance imaging (MRI) energy applied external to the body. The stent constitutes a metal scaffold. A... | 02/26/2008 |
| 7331992 | Anchoring device for an endoluminal prosthesis An anchoring device for incorporation into an endoluminal prosthesis to prevent migration thereof in a reliable way without the problems associated with intraluminal delivery of the prosthesis. The anchoring device allows smooth, efficient delivery of the prosthesis... | 02/19/2008 |
| 7329413 | Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof Coatings for implantable medical devices, and methods for fabricating thereof, are provided. The coatings include a first polymer layer and a second polymer layer, where the second polymer has a higher degree of hydration than the first polymer. ... | 02/12/2008 |
| 7329277 | Stent having helical elements An expandable stent comprised of a plurality of helical segments is disclosed. In one embodiment, the stent is generally cylindrical in shape having a cylindrical axis, and comprises a first and second set of helical segments. The helical segments in the first set a... | 02/12/2008 |
| 7323189 | Liquid and low melting coatings for stents A method for forming liquid coatings for medical devices such as stents and angioplasty balloons is provided. The liquid coatings can be made from biodegradable materials in liquid, low melting solid, or wax forms, which preferably degrade in the body without produc... | 01/29/2008 |
| 7324675 | Quantification of aortoiliac endoluminal irregularity A method to quantify the radial endoluminal irregularity of aortoiliac arteries is provided. Radial endoluminal outlines of a vessel of interest are determined. The cross sectional area is determined for the area outlined by each endoluminal outline. Using this cros... | 01/29/2008 |
| 7320675 | Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure A drug delivery system detects a cardiac condition indicative of a need for increasing a cardiac metabolic level and, in response, releases a drug into tissue or blood to shift a source of metabolically synthesized energy fueling cardiac contraction from fatty acid ... | 01/22/2008 |
| 7318836 | Covered stent A covered stent comprises a coiled sheet stent having at least a portion with open cell geometry and a graft material covering at least a portion of the coiled sheet stent. ... | 01/15/2008 |
| 7311980 | Polyactive/polylactic acid coatings for an implantable device A polymeric coating for a medical device that comprises poly(lactic acid) and a block copolymer including blocks of poly(ethylene glycol) and poly(butylene terephthalate) is provided. ... | 12/25/2007 |
| 7311970 | Medical device having surface modification with superoxide dismutase mimic A medical device comprising a substrate having a plasma polymerized functionality bonded to at least a portion of the substrate. A superoxide dismutase mimic agent having a complimentary functional group to the plasma polymerized functionality is bonded to the porti... | 12/25/2007 |
| 7311727 | Encased stent An encased stent that discourages restenosis by having a homogenous endothelial cell lining along the inner wall of the stent. The endothelial cell lining may be coated on the stent before the stent is placed in the artery, or the endothelial cell lining may be grow... | 12/25/2007 |
| 7309461 | Ultrasonic crimping of a varied diameter vascular graft A method of crimping a varied diameter graft is includes the steps of (i) providing a flat-woven tubular graft having an enlarged woven bulbous portion disposed between flat-woven tubular ends, wherein the flat-woven diameter of the bulbous section is greater than t... | 12/18/2007 |
| 7304277 | Resonator with adjustable capacitor for medical device An apparatus, system and method of a resonator device with an adjustable capacitor for allowing the resonance frequency (F) of the resonator device to continue to be matched to the Larmor frequency of the MRI system. The resonator device includes an inductor coil, a... | 12/04/2007 |
| 7300459 | Stent with covering and differential dilation A stent is provided with a multi-layer structure, combining one or more mesh layers with one or more film layers. The film layer(s) are configured to substantially prevent growth of an inner lining of a blood vessel, where the stent is placed, through the mesh layer... | 11/27/2007 |
| 7300457 | Self-supporting metallic implantable grafts, compliant implantable medical devices and methods of making same Implantable medical grafts fabricated of metallic or pseudometallic films of biocompatible materials having a plurality of microperforations passing through the film in a pattern that imparts fabric-like qualities to the graft or permits the geometric deformation of... | 11/27/2007 |
| 7297157 | Medical device with radiopacity An endoprosthesis, such as a stent, having a layer that can enhance the biocompatibility of the endoprosthesis, and methods of making the endoprosthesis are disclosed. ... | 11/20/2007 |
| 7297158 | Multilayer composite vascular access graft A multilayer composite vascular access graft and a method of constructing such a graft are disclosed. The mcVAG has improved performance characteristics, which include desirable handling characteristics such as ease of suturing, kink resistance and the ability to se... | 11/20/2007 |
| 7288111 | Flexible stent and method of making the same A stent that can be made of self-expandable members and balloon expandable members is described. The members can be held together by a polymer layer, polymer rings or discreet polymer connectors. Methods of making and using the stent are also described. ... | 10/30/2007 |
| 7279424 | Method for fabricating thin film magnetic heads using CMP with polishing stop layer A method is described for thin film processing using a selected CMP slurry with a silicon dioxide stop layer. The slurry includes an abrasive, preferably alumina, a corrosion inhibitor, preferably benzotriazole (BTA), and an oxidizer preferably hydrogen peroxide. Th... | 10/09/2007 |
| 7279664 | Resonator for medical device A resonator device including an induction coil, a conductive member positioned adjacent the induction coil, and a dielectric layer between at least a portion of the induction coil and the conductive member to form a capacitor structure. In one embodiment, the conduc... | 10/09/2007 |
| 7267686 | Implantable prosthetic valve A prosthetic valve for implantation within a fluid conducting lumen within a body includes an elongate generally cylindrical radially collapsible valve body scaffold defining a fluid passageway therethrough for retentive positioning within the lumen. A radially coll... | 09/11/2007 |
| 7261735 | Local drug delivery devices and methods for maintaining the drug coatings thereon Local drug delivery medical devices are utilized to deliver therapeutic dosages of drugs, agents or compounds directly to the site where needed. The local drug delivery medical devices utilize various materials and coating methodologies to maintain the drugs, agents... | 08/28/2007 |
| 7261734 | Resorption-controllable medical implants Bioresorbable medical implants are designed to have different resorption rates over time or over the topography of the implants. The resorption of the medical implants are controlled by including layers having differing resorption rates. The layers resorb sequential... | 08/28/2007 |