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Class 623/1.42 - Drug delivery


Subclass of Class 623 - Prosthesis (i.e., artificial body members), parts thereof, or aids and accessories therefor
Definition: Subject matter wherein the artificial blood vessel member
No. of patents: 456
Last issue date: 02/14/2012


1                      
NumberTitleIssue Date
8114152Stent coating
An expandable stent for use within a body passageway having a body member with two ends and a wall surface disposed between the ends. The body member has a first diameter to permit delivery of the body member into a body passageway and a second expanded diameter. Th...
02/14/2012
8114151Stent with tabs and holes for drug delivery
A stent can include a tubular body, a plurality of circumferential serpentine bands, a plurality of connectors extending between immediately adjacent serpentine bands, and a plurality of tabs. The plurality of tabs include peak tabs and trough tabs. Each peak tab an...
02/14/2012
8100963Biodegradable device
A device that is at least partially formed of a biodegradable polymer. The device can be at least partially formed by MEMS technology. The device can include one or more micro-structures that are also formed by MEMS technology. The device can include one or more age...
01/24/2012
8070797Medical device with a porous surface for delivery of a therapeutic agent
The present invention is generally directed to implantable medical devices for delivering therapeutic agents to the body tissue of a patient and methods for making such medical devices. In particular, the present invention is directed to implantable medical devices,...
12/06/2011
8070796Thrombosis inhibiting graft
A medical method that is adapted for introducing the medical device into the vascular system of a body which is designed to inhibit or prevent thrombosis after the insertion of the medical device. ...
12/06/2011
8066762Assembly for manufacturing an implantable polymeric medical device
A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are use...
11/29/2011
8062352Implantable device
The invention relates to an implantable device for local release of at least one drug at a predefined location in a natural cavity having a wall in the body of a mammal, characterized by at least one drug reservoir, which can be affixed in the cavity, the drug reser...
11/22/2011
8052745Endoprosthesis
In embodiments a stent includes a stent body and a wire-form carrying a drug located along the stent body. ...
11/08/2011
8048149Intraluminal stent including therapeutic agent delivery pads, and method of manufacturing the same
An intraluminal stent, an intraluminal stent delivery system, and a method of manufacturing an intraluminal stent. The stent comprises a body and at least one pad operably attached to the stent body. The pad includes at least one therapeutic agent disposed thereon. ...
11/01/2011
8048150Endoprosthesis having a fiber meshwork disposed thereon
The present invention comprises a medical device having an underlying structure on which is disposed a fiber meshwork composed of one or more fibers of substantially uniform diameter. The fiber meshwork may optionally have a multi-layer structure disposed upon it. E...
11/01/2011
8043367Stents formed from polymer-bioceramic composite with radiopaque bioceramic particles
Implantable medical devices fabricated at least in part of a polymer-bioceramic composite having bioceramic particles with radiopaque functional groups grafted to a surface of the bioceramic particles are disclosed. Implantable medical devices fabricated at least in...
10/25/2011
8038709Local delivery of therapeutic agent to heart valves
The present invention relates to implantable medical devices and methods that employ these medical devices to treat heart valves. In one embodiment, a medical device is provided comprising a body. The body may have a portion thereof including therapeutic agent and c...
10/18/2011
8029561Drug combination useful for prevention of restenosis
The current invention comprises an approach to solving the clinical problem of restenosis, which involves the administration of combinations of drugs to patients undergoing PTCA or stent implantation. In one embodiment of the invention, an antiproliferative agent su...
10/04/2011
8016880Stent having spiral channel for drug delivery
A drug delivery stent is formed by a metallic or polymeric tubular strut which is shaped into a generally cylindrical configuration, the tubular strut having a central lumen for containing a therapeutic substance or drug therein. The tubular strut has a continuous c...
09/13/2011
8012200Endovascular magnetic method for targeted drug delivery
The method for endovascular magnetic targeting drug delivery in a vascular wall and adjoining tissues, wherein an endovascular mesh stent with paramagnetic properties is preliminary implanted in the area of interest by a catheter, a polymeric magneto-responsive carr...
09/06/2011
7998195Device with engineered surface architecture coating for controlled drug release
In one embodiment of the present invention a coating topology, or engineered surface architecture that may be referred to as a microdroplet deposited engineered surface architecture is provided. A plurality of drops are placed on the stent with the purpose, of build...
08/16/2011
7967856Microtubes for therapeutic delivery
A medical implant that delivers therapeutic via microtubes and a method of making the same is provided. In one embodiment a biologically implantable structure adapted to fit within the body of a patient is provided. This structure may have a plurality of individual ...
06/28/2011
7967855Coated medical device
A stent that is adapted for introduction into a body passageway and which releases at least one biological agent after being inserted in the body passageway. The release of the at least one biological agent can be a controlled release via molecular diffusion through...
06/28/2011
7955382Endoprosthesis with adjustable surface features
Endoprostheses (e.g., stents) containing adjustable surfaces are disclosed. ...
06/07/2011
7951193Drug-eluting stent
A stent for delivering therapeutic agents to a body lumen includes a plurality of circumferential serpentine bands with each band comprising a plurality of struts. At least one strut has at least one first well region and at least one second well region. The at leas...
05/31/2011
7935143Stent formed from polymer-bioceramic composite with radiopaque bioceramic particles
Implantable medical devices fabricated at least in part of a polymer-bioceramic composite having bioceramic particles with radiopaque functional groups grafted to a surface of the bioceramic particles are disclosed. Implantable medical devices fabricated at least in...
05/03/2011
7931683Articles having ceramic coated surfaces
According to an aspect of the invention, articles are provided which comprise a substrate and a ceramic coating which covers at least a portion of the substrate surface. The ceramic coating includes raised ceramic shells connected by a ceramic layer that is conforma...
04/26/2011
7922760In situ trapping and delivery of agent by a stent having trans-strut depots
A method of delivering an agent into a bodily lumen, the method comprising: implanting an implantable medical device into a treatment site of a lumen, the device having an abluminal face and a luminal face, wherein the device includes depots that extend from an open...
04/12/2011
7914573Polymeric stent having modified molecular structures
A biocompatible material may be configured into any number of implantable medical devices including intraluminal stents. Polymeric materials may be utilized to fabricate any of these devices, including stents. The stents may be balloon expandable or self-expanding. ...
03/29/2011
7909865Expandable medical device for delivery of beneficial agent
An expandable medical device having a plurality of elongated struts, the plurality of elongated struts being joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter...
03/22/2011
7909864Implantable medical devices having adjustable pore volume and methods for making the same
The present invention is directed to implantable medical devices which may be used for controllably releasing a therapeutic agent within a patient and methods for making the same. These medical devices may include porous coatings, which may be polymer-free, located ...
03/22/2011
7901451Drug-delivery endovascular stent and method for treating restenosis
A radially expandable, endovascular stent designed for placement at a site of vascular injury, for inhibiting restenosis at the site, a method of using, and a method of making the stent. The stent includes a radially expandable body formed of one or more metallic fi...
03/08/2011
7901453Coated implantable medical device
A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract, and at least one layer 18 of an immunosuppressive agent posited over at...
03/08/2011
7901452Method to fabricate a stent having selected morphology to reduce restenosis
Methods of fabricating a stent and a stent having selected morphology on abluminal and luminal surfaces of the stent are disclosed. ...
03/08/2011
7896914Coated implantable medical device
A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; ...
03/01/2011
7875073Block copolymers of acrylates and methacrylates with fluoroalkenes
A block copolymer comprising a fluorinated block and a non-fluorinated block and method of making the block copolymer are provided. Also provided herein are a coating on an implantable device comprising the block copolymer and method of using the implantable device....
01/25/2011
7867275Coated implantable medical device method
A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; ...
01/11/2011
7850727Expandable medical device for delivery of beneficial agent
An expandable medical device has a plurality of elongated struts joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. At least one of the plurality of struts in...
12/14/2010
7850728Expandable medical device for delivery of beneficial agent
An expandable medical device having a plurality of elongated struts, the plurality of elongated struts being joined together to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter...
12/14/2010
7846202Coated implantable medical device
A coated implantable medical device 10 includes a structure 12 adapted for introduction into the vascular system, esophagus, trachea, colon, biliary tract, or urinary tract; at least one coating layer 16 posited on one surface of the structure; ...
12/07/2010
7846201Magnetically-driven biodegradable gene delivery nanoparticles formulated with surface-attached polycationic complex
A particle including a matrix-forming agent and a polyelectrolyte-amphiphilic agent adduct wherein the polyelectrolyte-amphiphilic agent adduct is in physical communication with the matrix-forming agent. The particle further includes a coated magnetic field-responsi...
12/07/2010
7842083Expandable medical device with improved spatial distribution
An expandable medical device having a plurality of elongated struts, the plurality of elongated struts being joined together by ductile hinges to form a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having...
11/30/2010
7833266Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
The invention is directed to a stent that delivers multiple therapeutic regimens from different regions of the stent. ...
11/16/2010
7824441Stent with drug coating
Coatings for stents that include a polymer and a drug are provided. A method of forming the coatings is also provided. ...
11/02/2010
7824440Stent with drug coating
Coatings for stents that include a polymer and a drug are provided. A method of forming the coatings is also provided. ...
11/02/2010
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