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| Number | Title | Issue Date |
| 7351421 | Drug-eluting stent having collagen drug carrier chemically treated with genipin A method for treating vulnerable plaques of a patient, comprising: providing a biodegradable stent comprising a first supporting zone made of a first biodegradable material, wherein the supporting zone comprises at least a portion of continuous circumference of the ... | 04/01/2008 |
| 7306624 | Implantable intraluminal device and method of using same in treating aneurysms A method for reducing blood flow to an aneurysm proximate to a bifurcation having a source blood vessel a first branch vessel and a second branch vessel, the method comprising: providing a first mesh-like tube of bio-compatible material, the first mesh-like tube exh... | 12/11/2007 |
| 7297158 | Multilayer composite vascular access graft A multilayer composite vascular access graft and a method of constructing such a graft are disclosed. The mcVAG has improved performance characteristics, which include desirable handling characteristics such as ease of suturing, kink resistance and the ability to se... | 11/20/2007 |
| 7288084 | Drug-loaded medical device A medical device is designed to be placed in a patient's body and release one or more therapeutic agents therefrom. The medical device includes an elongated member defining a passage for passing bodily fluids therethrough and at least one enclosed internal space for... | 10/30/2007 |
| 7244271 | Self-sealing PTFE vascular graft and manufacturing methods An implantable microporous ePTFE tubular vascular graft exhibits long term patency, superior radial tensile strength and suture hole elongation resistance. The graft includes a first ePTFE tube and a second ePTFE tube circumferentially disposed over the first tube. ... | 07/17/2007 |
| 7147455 | Method and apparatus for shape forming endovascular graft material Methods and devices for molding a desired configuration into an endovascular graft section that is made of a plurality of layers of fusible material. Layers of fusible material are disposed on a shape forming mandrel with seams in the layers that may be configured t... | 12/12/2006 |
| 7059172 | Phase flow measurement in pipes using a density meter The present invention discloses an apparatus for determining the density and the phase fraction of a fluid flowing in a conduit. The apparatus comprises a fiber optic density meter situated along the conduit that provides a signal indicative of the density of the fl... | 06/13/2006 |
| 7044965 | Therapeutic cellular stent A vascular stent carries living therapeutic cellular material. The stent in widely implantable over the vascular system, and allows either localized or systemic delivery of the therapeutic products produced by the cellular material to thereby enhance patient treatme... | 05/16/2006 |
| 7022135 | Film with highly porous vascular graft prostheses A vascular graft prosthesis having ingrowth-permissive lumenal wall features with a thin film or layer of sealant-like material placed at a lumenal wall location to promote improved transmural tissue growth and healing. ... | 04/04/2006 |
| 6994722 | Implant having improved fixation to a body lumen and method for implanting the same A device for improving fixation and sealing of a prosthetic component when implanted in a body lumen during laparoscopic, endovascular, or open surgical procedures. In one embodiment, the prosthetic component comprises a graft having a hem defining an interior space... | 02/07/2006 |
| 6971259 | Fluid density measurement in pipes using acoustic pressures The density of at least one fluid in a pipe is determined using a pair of effective sound speeds a1eff and a2eff of the fluid/pipe system. The pair of effective sound speed measurements is taken at two sensing regions along the pipe wherein eac... | 12/06/2005 |
| 6827737 | EPTFE covering for endovascular prostheses and method of manufacture An implantable composite device for regulated delivery of bioactive agents to the site of implantation includes at least two zones of distinct porosities through its cross-section. One zone is of a sufficient porosity to permit regulated transport of bioactive agent... | 12/07/2004 |
| 6723120 | Medicated porous metal prosthesis A porous prosthesis for delivering a medication to the site of implantation is disclosed. ... | 04/20/2004 |
| 6719783 | PTFE vascular graft and method of manufacture An implantable microporous ePTFE tubular vascular graft exhibits long term patency, superior radial tensile strength and suture hole elongation resistance. The graft includes a first ePTFE tube and a second ePTFE tube circumferentially disposed over the first tube. ... | 04/13/2004 |
| 6673108 | Transmural concentric multilayer ingrowth matrix within well-defined porosity A multilayer ingrowth matrix is constructed within well-defined porosity of a prosthetic material. The matrix consists of either proteinaceous or synthetic layers or gradients, or a combination of proteinaceous and synthetic layers or gradients. Each laye... | 01/06/2004 |
| 6579313 | Methods for implanting cells A method for implanting cells onto a prosthesis includes the steps of: (a) providing a prosthesis including a porous tube, where at least 25% of the pores on the inner surface of the tube have diameters of more than about 40 μm, at least 25% of the pores... | 06/17/2003 |
| 6440166 | Multilayer and multifunction vascular graft A multi-zone, multifinctional graft with two or more zones that have different chemical and biological characteristics is provided. The vascular conduit that has of an inner zone that is permanently non-thrombogenic and anti-proliferative, and one or more... | 08/27/2002 |
| 6428571 | Self-sealing PTFE vascular graft and manufacturing methods An implantable microporous ePTFE tubular vascular graft exhibits long term patency, superior radial tensile strength and suture hole elongation resistance. The graft includes a first ePTFE tube and a second ePTFE tube circumferentially disposed over the f... | 08/06/2002 |
| 6406488 | Healing transmyocardial implant A transmyocardial implant establishes a blood flow path through a myocardium between a heart chamber and a lumen of a coronary vessel residing on an exterior of the heart. The implant includes a coronary portion sized to be received within the vessel. A m... | 06/18/2002 |
| 6371982 | Graft structures with compliance gradients A distensible artificial tubular graft structure is provided that has a compliance gradient. The graft may be used to repair a patient's body organ tubing. For example, the graft may be used to replace or supplement portions of a patient's vascular system... | 04/16/2002 |
| 6352555 | Methods for implanting cells Disclosed herein is a method for implanting cells onto a prosthesis, including the steps of: (a) providing a prosthesis including a porous tube, where at least 25% of the pores on the inner surface of the tube have diameters of more than about 40 μm, at ... | 03/05/2002 |
| 6287337 | Multi-stage prosthesis A porous tube suitable for use as a vascular graft prosthesis and a method of making it is disclosed. It has a structure of porous polytetrafluoroethylene having a fibrous structure of nodes and fibers connecting the nodes together and an integrated intra... | 09/11/2001 |
| 6261320 | Radioactive vascular liner Disclosed is a radioactive tubular prosthesis formed by rolling a flexible sheet around a longitudinal axis. Preferably, the prosthesis is self expandable under the radially outwardly directed spring bias of the rolled sheet. At least a portion of the she... | 07/17/2001 |
| 6001125 | PTFE vascular prosthesis and method of manufacture An implantable microporous ePTFE tubular vascular graft exhibits long term patency, superior radial tensile strength and suture hole elongation resistance. The graft includes a first ePTFE tube and a second ePTFE tube circumferentially disposed over the f... | 12/14/1999 |
| 5824050 | Prosthesis with in-wall modulation The wall of a prosthesis has a region which modulates communication through the porosity of the wall. The prosthesis is unitary, but may be assembled in successive bodies which are coalesced, so that the porous microstructure changes distinctly at stages ... | 10/20/1998 |
| 5728150 | Expandable microporous prosthesis Disclosed is a tubular prosthesis formed by rolling a perforated sheet around a longitudinal axis. Preferably, the prosthesis is self expandable under the radially outwardly directed spring bias of the rolled sheet. The perforations in the sheet are confi... | 03/17/1998 |
| 5383925 | Three-dimensional braided soft tissue prosthesis The present invention provides a soft tissue prosthesis which is formed from a three-dimensional braided structure. The three-dimensional braided structure preferably may be made in the form of a solid three-dimensional braid, a three-dimensional braid ha... | 01/24/1995 |
| 5370682 | Solid woven tubular prosthesis A solid woven tubular prosthesis having sufficient inherent wall stiffness so as to be radially self-supporting. The solid woven prosthesis is capable of being formed with a smooth, continuous inner wall that improves the hemodynamic flow with respect to ... | 12/06/1994 |
| 5171261 | Vascular prosthesis, manufacturing method of the same, and substrate for vascular prothesis The invention relates to a vascular prosthesis wherein, fragments of biological tissues such as vascular tissues, connective tissues, fat tissues and muscular tissues and/or cells composing vascular walls such as vascular endothelial cells, smooth muscle ... | 12/15/1992 |
| 5104403 | Vascular prosthesis containing in the wall microcapsules, including hormone-producing cells A vascular prosthesis having a low porosity outer material such as FTFE, and an inner synthetic tubular mesh. Semi-permeable microcapsules that contain hormone-producing cells, are placed between the outer material and the inner mesh. The microcapsules ar... | 04/14/1992 |
| 4822352 | Medical tubes with porous textured walls Disclosed is a medical tube comprising a mono-layer medical tube comprising a high molecular weight compound, wherein the inner texture of a tube wall constituting the tube is porous and no skin layer is present on the inner face of the tube wall. The por... | 04/18/1989 |
| 4816339 | Multi-layered poly(tetrafluoroethylene)/elastomer materials useful for in vivo implantation Biologically compatible materials capable of being formed into implants, comprising layers of poly(tetrafluoroethylene) and mixtures of poly(tetrafluoroethylene) and elastomer, having excellent compliance, strength, elasticity and suturability are disclos... | 03/28/1989 |
| 4743252 | Composite grafts Composite grafts are provided that have a porous wall structure to permit ingrowth thereinto under in vivo conditions but which include a generally non-porous membrane in the wall to prevent substantial fluid passage therethrough so as to provide an impla... | 05/10/1988 |
| 4647416 | Method of preparing a vascular graft prosthesis A ribbed, porous tube suitable for use as a vascular graft prosthesis is prepared by scoring a stretched or unstretched tube of PTFE, stretching the tube at 200°-320° C. to develop the desired porosity, and heat setting the scored, stretched tube at 327... | 03/03/1987 |
| 4553272 | Regeneration of living tissues by growth of isolated cells in porous implant and product thereof A method of repair of patient tissues by implant including providing a living cell sample which is introduced into an implant member having a porous open structure. The cell sample may be cultured in the implant. The implant is secured to the patient, as ... | 11/19/1985 |
| 4355426 | Porous flexible vascular graft Novel cardiovascular prosthetic devices or implants having many useful cardiovascular applications comprise a porous surface and a network of interconnected interstitial pores below the surface in fluid flow communication with the surface pores. Tissue fo... | 10/26/1982 |
| 4321711 | Vascular prosthesis A vascular prosthesis comprising a porous tubing of polytetrafluoroethylene containing an anti-coagulant substance and bonded to its outside surface a porous elastomer coating containing substance which counteracts the anti-coagulant substance is disclose... | 03/30/1982 |
| 4286341 | Vascular prosthesis and method of making the same A vascular prosthesis and its method of fabrication. The prosthesis takes the form of a flexible and conformable support tube having a luminal surface formed of a smooth, homogenous, and substantially non-thrombogenic hydrogel having relatively small pore... | 09/01/1981 |
| 4229838 | Vascular prosthesis having a composite structure A vascular prosthesis having a composite structure of a porous tubing of polytetrafluoroethylene with polyethyleneimine in the pores of the tubing, the polyethyleneimine being water-insolubilized with the amino groups quaternized and having heparin ionica... | 10/28/1980 |
| 4208745 | Vascular prostheses composed of polytetrafluoroethylene and process for their production A vascular prosthesis comprising a tubing of porous polytetrafluoroethylene, the polytetrafluoroethylene tubing having a fibrous structure of nodes and fibers connecting the nodes together and having a structure in which the fibrous structure at the insid... | 06/24/1980 |