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| Number | Title | Issue Date |
| 8190253 | Collecting activity information to evaluate incontinence therapy A medical device delivers a therapy to a patient. The medical device may periodically determine an activity level of the patient, and associate each determined activity level with a current therapy parameter set. A value of at least one activity metric is determined... | 05/29/2012 |
| 8170661 | Pacing system controller integrated into indeflator Systems and methods for temporarily pacing a patient's heart are provided. One system includes a vascular treatment system having a vascular access system and a therapy system. The therapy system includes an indeflator and an elongate medical device and the elongate... | 05/01/2012 |
| 8160696 | Nerve stimulator and method using simultaneous electrical and optical signals An apparatus and method for stimulating animal tissue (for example to trigger a nerve action potential (NAP) signal in a human patient) by application of both electrical and optical signals for treatment and diagnosis purposes. The application of an electrical signa... | 04/17/2012 |
| 8121679 | Transcutaneous electrical nerve stimulator with hot or cold thermal application A Transcutaneous Electrical Nerve Stimulator (TENS) and electrode pad that is capable simultaneously of delivering hot or cold thermal therapy for the relief of pain. ... | 02/21/2012 |
| 8078275 | Regulation of neurotrophins Disclosed are methods for regulating neurotrophin levels within a human body. The invention utilizes an implantable signal generator to deliver stimulation to neural tissue elements. Alternatively, an implantable pump may be utilized to delivery one or more drugs. T... | 12/13/2011 |
| 8019414 | Treating cancer using electromagnetic fields in combination with other treatment regimens Chemotherapeutic treatment for certain cancers may be combined with low intensity, intermediate frequency alternating electric fields that are tuned to a particular type of target cell. When the tuned fields were combined with Paclitaxel, Doxorubicin or Cyclophospha... | 09/13/2011 |
| 8014857 | Implantable shock electrode line and implantable defibrillation arrangement An implantable shock electrode line having a proximal terminal for connection to an implantable defibrillator, an elongated flexible line body, and a shock electrode and a drug delivery device arranged at or near the distal end of the line body. A drug depot connect... | 09/06/2011 |
| 8010189 | SPG stimulation for treating complications of subarachnoid hemorrhage A method is provided including identifying that a subject has suffered a subarachnoid hemorrhage (SAH), and treating a complication of the SAH by stimulating at least one site of the subject in conjunction with treating the SAH, the site selected from the group cons... | 08/30/2011 |
| 8005540 | Monitoring of chronobiological rhythms for disease and drug management using one or more implantable device The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm wh... | 08/23/2011 |
| 7979121 | Method and apparatus for physiological treatment with electromagnetic energy An electromagnetic device and method of operation thereof are disclosed. The electromagnetic device contains an electromagnetic field generator, a microcurrent generator and a photonic accumulator. The electromagnetic field generator generates broadband electromagne... | 07/12/2011 |
| 7917208 | Medical device for controlled drug delivery and cardiac monitoring and/or stimulation Medical device and methods are provided for controlled drug delivery in a cardiac patient. The device includes an implantable drug delivery module comprising reservoirs containing a drug and a control means for selectively releasing an effective amount of drug from ... | 03/29/2011 |
| 7899528 | Method and apparatus to monitor patients and treat with intraosseous fluids Automatic external defibrillator apparatus may be provided for use in cooperation with an intraosseous apparatus. Apparatus and methods may also be provided to execute protocols calling for external defibrillation and drug delivery. The disclosure provides a medical... | 03/01/2011 |
| 7894892 | Therapy-selection methods for implantable heart monitors An implantable heart-monitoring device comprising one or more leads for sensing electrical signals of a patient's heart a therapy circuit for delivering pharmaceuticals to the patient; and a monitoring circuit coupled to the one or more leads and to the therapy circ... | 02/22/2011 |
| 7890166 | Regional therapies for treatment of pain Enhanced therapies for treating pain are described. The therapies include subcutaneous stimulation of tissue in proximity to a source of pain at low frequencies (less than about 20 Hz) and high frequencies (greater than about 50 Hz). The therapies further include ad... | 02/15/2011 |
| 7885710 | Method and apparatus for tissue protection against ischemia using remote conditioning A stimulation system delivers stimulation to protect an ischemic region of a body from tissue damage caused by ischemia. The stimulation is delivered to one or more stimulation sites remote from the ischemic region to elicit a physiological effect that protects the ... | 02/08/2011 |
| 7877137 | Thrombolysis and chronic anticoagulation therapy Method and systems of treating a patient with at least one of a myocardial infarction, a stroke, and a pulmonary embolism include providing a stimulator coupled to at least one electrode and a catheter, configuring one or more stimulation parameters to treat at leas... | 01/25/2011 |
| 7856264 | Systems and methods for patient interactive neural stimulation and/or chemical substance delivery Systems and methods for patient interactive neural stimulation and/or chemical substance delivery are disclosed. A method in accordance with one embodiment of the invention includes affecting a target neural population of the patient by providing to the patient at l... | 12/21/2010 |
| 7840263 | Method and apparatus for device controlled gene expression A gene regulatory system controls gene therapy by emitting one or more forms of energy that regulate gene expression by triggering promoters. The system includes a sensor to sense a signal indicative of a need for the gene therapy as well as responses to the gene th... | 11/23/2010 |
| 7840264 | System and method for breaking reentry circuits by cooling cardiac tissue Systems and methods to inhibit the conduction of certain spurious electrical impulses in the heart. Inhibition of spurious electrical impulses in the heart is accomplished by cooling one or more targeted portions of the heart. Optionally, inhibition of spurious elec... | 11/23/2010 |
| 7809438 | Methods and systems for treating arrhythmias using a combination of vibrational and electrical energy Methods and apparatus for cardiac pacing, cardioversion and defibrillation rely on delivering ultrasonic or other vibrational energy in combination with electrical energy to the heart, usually after the onset of an arrhythmia. A vibrational transducer and suitable e... | 10/05/2010 |
| 7801604 | Controlled titration of neurostimulation therapy Described herein are methods and devices that utilize electrical neural stimulation to treat heart failure by modulating a patient's autonomic balance in a manner that inhibits sympathetic activity and/or augments parasympathetic activity. Because other therapies fo... | 09/21/2010 |
| 7792576 | Method of treatment for central nervous system injury Injuries to the central nervous system, particularly spinal cord injuries, are treated by administering a purine nucleoside or analog to the patient and, optionally, electrically stimulating the site of injury. ... | 09/07/2010 |
| 7787946 | Patient monitoring, diagnosis, and/or therapy systems and methods Systems and methods involve an implantable device configured to perform at least one cardiac-related function, a patient-external respiratory therapy device, and a communication channel configured to facilitate communication between the implantable device and the re... | 08/31/2010 |
| 7783348 | Stimulation device for treating osteoarthritis A device for providing therapeutic treatment to a body part such as a knee joint to promote healing of the body part, including a signal generator for generating a pulsed electromagnetic field to electromagnetic stimulators based upon a selected treatment mode, a co... | 08/24/2010 |
| 7778702 | Combined parasympathetic stimulation and drug therapy A method is provided for treating a subject, including applying a current to a site of the subject selected from the list consisting of: a vagus nerve of the subject, an epicardial fat pad of the subject, a pulmonary vein of the subject, a carotid artery of the subj... | 08/17/2010 |
| 7774057 | Method and apparatus for device controlled gene expression for cardiac protection A gene regulatory system detects ischemia events and is capable of delivering a biologic therapy in response to the detection of an ischemic event or the reception of a command. The biologic therapy protects the heart from ischemic damage by regulating the expressio... | 08/10/2010 |
| 7769443 | Implantable reel for coiling an implantable elongated member An implantable spool is used for spooling the excess wiring associated with a lead that extends between at least one electrode and a pulse generator of an electrical stimulation implant system. The present invention also has application to providing a spool for coil... | 08/03/2010 |
| 7769444 | Method of treating cardiac arrhythmias A method of treating cardiac arrhythmias resulting from errant electrical signals conducted through the cardiac tissue from a source location. The magnitude of the errant signals is reduced by shunting electrical signals from the source location with an electrically... | 08/03/2010 |
| 7764996 | Monitoring of chronobiological rhythms for disease and drug management using one or more implantable device The health state of a subject is automatically evaluated or predicted using at least one implantable device. In varying examples, the health state is determined by sensing or receiving information about at least one physiological process having a circadian rhythm wh... | 07/27/2010 |
| 7764995 | Method and apparatus to modulate cellular regeneration post myocardial infarct A system delivers cardiac pacing therapy and chemical and/or biological therapy to modulate myocardial tissue growth in a heart after myocardial infarction (MI). The system includes an agent delivery device to release one or more agents to an MI region to modulate m... | 07/27/2010 |
| 7761149 | Electrical stimulus allergy treatment method A method of reducing the symptoms of allergy including exposing the patient to the allergenic substance in containers and applying an electrical stimulus device to acupuncture meridian points on the patient's body to clear blockages in the flow of life-energy of the... | 07/20/2010 |
| 7742811 | Implantable device and method for the electrical treatment of cancer An implantable electrical method and apparatus for the treatment of cancer tumors based on the usage of various levels of electrical fields and current to assist in specific ways to reduce tumor size. The appropriate voltage, currents, and time duration as well as t... | 06/22/2010 |
| 7734342 | Techniques for positioning therapy delivery elements within a spinal cord or brain Apparatus and techniques to address problems associated with lead migration, patient movement or position, histological changes, neural plasticity or disease progression. Disclosed are techniques for implanting a lead having therapy delivery elements, such as electr... | 06/08/2010 |
| 7729761 | Method and apparatus for controlled gene or protein delivery An implantable system which includes a gene/protein delivery device and a pulse generator, as well as method of preparing the gene/protein delivery device and using the system, are provided. In one embodiment, the implantable system detects a predetermined condition... | 06/01/2010 |
| 7725178 | Method and system for the prediction of cardiac arrhythmias, myocardial ischemia, and other diseased condition of the heart associated with elevated sympathetic neural discharges Methods and systems are provided for determining an increased likelihood of the occurrence of a cardiac arrhythmia, myocardial ischemia, congestive heart failure and other diseased conditions of the heart associated with elevated sympathetic neural discharges in a p... | 05/25/2010 |
| 7720535 | Pacing management during cardiopulmonary resuscitation Systems and methods provide for coordinated cardiac pacing with delivery of cardiopulmonary resuscitation (CPR) to a patient. Managing cardiac pacing in a patient during a cardiac arrhythmia involves detecting a cardiac arrhythmia using a patient implantable medical... | 05/18/2010 |
| 7653433 | Method of treating depression, mood disorders and anxiety disorders using neuromodulation The present application involves a method and a system for using electrical stimulation and/or chemical stimulation to treat depression. More particularly, the method comprises surgically implanting an electrical stimulation lead and/or catheter that is in communica... | 01/26/2010 |
| 7630761 | Method and apparatus for modifying tissue to improve electrical stimulation efficacy A biologic agent delivery system provides for delivery of a biologic agent to a stimulation site to which electrical stimulation pulses are to be delivered from an electrical stimulation device. Examples of the electrical stimulation device include cardiac pacemaker... | 12/08/2009 |
| 7620451 | Methods and apparatus for pulsed electric field neuromodulation via an intra-to-extravascular approach Methods and apparatus are provided for pulsed electric field neuromodulation via an intra-to-extravascular approach, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in... | 11/17/2009 |
| 7599737 | Medical device for neural stimulation and controlled drug delivery Medical devices and methods are provided for electrical stimulation of neural tissue and controlled drug delivery to a patient. The device includes an implantable drug delivery module which comprises a plurality of reservoirs, a release system comprising at least on... | 10/06/2009 |
